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Best abstract: A multicentre, double-blind, placebo-controlled phase3 study of ustekinumab, a human interleukins-12/23p40 mab, in moderate-severe Crohn’s Disease refracto-ry to anti-TNFα: UNITI-1
Source: Presentation - ECCO 2016 Amsterdam Congress - Scientific session 5: Challenging dogmas – from clinical trials to clinical practice (Keywords:IBD, CD, ustekinomab)
Authors: Paul Rutgeerts
Best abstract: A phase III randomised controlled trial of Cx601, expanded allogeneic adipose-derived mesenchymal stem cells (eASC), for complex perianal fistulae in Crohn’s Disease
Source: Presentation - ECCO 2016 Amsterdam Congress - Scientific session 1: Cell therapy: Ready for clinical practice? (keywords: fistula, CD, trials, cell therapy)
Authors: Julián Panés
Best abstract: A randomised, double-blind placebo- controlled phase 2a induction study of MEDI2070 (anti-p19 antibody) in patients with active Crohn’s Disease who have failed anti-TNF antibody therapy
Source: Presentation - ECCO 2015 Barcelona Congress - Scientific session 10: New therapies and strategies (Keywords: clinical trials, CD)
Authors: Bruce E. Sands
Best abstract: A variable number of tandem repeat polymorphism in the promotor region of the neonatal Fc receptor affects anti-TNF serum levels in IBD
Source: Presentation - ECCO 2016 Amsterdam Congress - Scientific session 2: Application of genetic testing in understanding and managing IBD (Keywords: adalimumab, anti-TNF, biologic treatment, genetic, IBD, CD, UC, pharmacogenomics, pharmacokinetics, trough levels, neonatal FC receptor)
Authors: Thomas Billiet
Best abstract: Adalimumab and infliximab levels in neonates
Source: Presentation - ECCO 2015 Barcelona Congress - Scientific session 2: Pharmacokinetics in clinical practice (Keywords: adalimumab, anti-TNF, AZA, biologic treatment, IBD, CD, UC, immunosuppressive agents, infliximab, pregnancy, birth outcome, clearance)
Authors: Mette Julsgaard
Best abstract: Adding ciprofloxacin to adalimumab results in a higher fistula closure rate in perianal fistulizing Crohn's disease
Source: Presentation - ECCO'12 Barcelona Congress
Authors: Peter Dewint
Best abstract: Adenomas in patients with Inflammatory Bowel Disease: Increased risk of advanced neoplasia
Source: Presentation - ECCO'12 Barcelona Congress
Authors: Fiona van Schaik
Best abstract: Agreement among central readers in the evaluation of endoscopic disease activity in Crohn's Disease
Source: Presentation - ECCO 2014 Copenhagen Congress - Scientific session 11: Challenging current practice: Value-based healthcare for IBD: Best abstract: Agreement among central readers in the evaluation of endoscopic disease activity in Crohn's Disease (Keywords: endoscopic asessment, CD, trials)
Authors: Reena Khanna
Best abstract: AlphaE integrin expression as a predictive biomarker for induction of clinical remission by etrolizumab: Analysis of a phase II trial in moderate-to-severely active Ulcerative Colitis
Source: Presentation - ECCO 2014 Copenhagen Congress - Scientific session 4: Tomorrow’s therapy: Best abstract: AlphaE integrin expression as a predictive biomarker for induction of clinical remission by etrolizumab: Analysis of a phase II trial in moderate-to-severely active Ulcerative Colitis (Keywords: UC, etrolizumab)
Authors: Mary Keir
Best abstract: Anti TNF- alpha; Therapy is a major cost driver in Inflammatory Bowel Disease: Results from the COIN study
Source: Presentation - ECCO'12 Barcelona Congress
Authors: Mirthe Van der Valk
Best abstract: Anti-TNF in patients with an early course of Crohn´s Disease - a prospective observational Study in Germany
Source: Presentation - ECCO 2013 Vienna Congress - Scientific Session 1: Early stage IBD
Authors: Bernd Bokemeyer
Best abstract: Anti-TNF therapy is associated with increased risk of postoperative morbidity after surgery for ileocolonic Crohn’s Disease: Outcome analysis in a prospective nationwide cohort of 592 patients conducted by the GETAID chirurgie group
Source: Presentation - ECCO 2016 Amsterdam Congress - Scientific session 10: Surgical and endoscopic FAQs in IBD (Keywords: complications, CD, ileocecal resection, postoperative)
Authors: Antoine Brouquet
Best abstract: Autophagy regulates dendritic cell migration through Rac1 – implications for thiopurine therapy
Source: Presentation - ECCO 2016 Amsterdam Congress - Scientific session 2: Application of genetic testing in understanding and managing IBD (Keywords: TG, autophagy, AZA, dendritic cell, genetic, IBD, mucosal immunology, SNP)
Authors: Manon Wildenberg
Best abstract: Azathioprine dose reduction in Inflammatory Bowel Disease patients on combination therapy: A prospective study
Source: Presentation - ECCO 2016 Amsterdam Congress - Scientific session 3: Resolution of inflammation (Keywords: mercaptopurine, anti-TNF, AZA, IBD, monitoring, phamarcokinetics,trough levels)
Authors: Xavier Roblin
Best abstract: Bronchopulmonary manifestations in Inflammatory Bowel Diseases: A retrospective study from the GETAID
Source: Presentation - ECCO'11 Dublin Congress
Authors: Matthieu Allez
Best abstract: Budesonide MMX®9 mg for inducing remission in patients with mild-to-moderate Ulcerative Colitis not adequately controlled with oral 5-ASAs
Source: Presentation - ECCO 2015 Barcelona Congress - Scientific session 4: The gut barrier under attack: Therapeutic implications (Keywords: 5-aminosalicylate, 5.ASA, budesonide, clinical trials, corticosteroids)
Authors: David T. Rubin
Best abstract: Card9 is a crucial adapter protein for gastro-intestinal immune response
Source: Presentation - ECCO'12 Barcelona Congress
Authors: Harry Sokol
Best abstract: Caspase 8 maintains epithelial cell adhesion and intestinal homeostasis in vivo through regulation of clathrin-dependent endocytosis and autophagy
Source: Presentation - ECCO 2013 Vienna Congress - Scientific session 2: Preventing progression in IBD
Authors: Guillaume Pineton de Chambrun
Best abstract: Circadian clock function maintains mucosal architecture and protects against intestinal inflammation in mice
Source: Presentation - ECCO 2014 Copenhagen Congress - Scientific session 1: Neglected cells as potential targets: Best abstract: Circadian clock function maintains mucosal architecture and protects against intestinal inflammation in mice
Authors: Christian Sina
Best abstract: Comparison of adalimumab monotherapy and a combination with azathioprine for patients with Crohn’s Disease: A prospective, multicentre, open-labeled clinical trial (DIAMOND study)
Source: Presentation - ECCO 2016 Amsterdam Congress - Scientific session 3: Resolution of inflammation (Keywords: adalimumab, AZA)
Authors: Takayuki Matsumoto