S. Jeuring*^{1, 2}, T. Van den Heuvel^{1, 2}, M. Zeegers^{3, 4}, W. Hameeteman¹, M. Romberg-Camps⁵, L. Oostenbrug⁶, A. Masclee^{1, 2}, D. Jonkers^{1, 2}, M. Pierik^{1, 2}

¹Maastricht University Medical Center+, Internal Medicine - Division Gastroenterology-Hepatology, Maastricht, Netherlands, ²Maastricht University Medical Center+, NUTRIM, School for Nutrition, Toxicology and Metabolism, Maastricht, Netherlands, ³University of Birmingham, Public Health, Epidemiology and Biostatistics, Birmingham, United Kingdom, ⁴Maastricht University Medical Center+, Complex Genetics, Cluster of Genetics and Cell Biology, Maastricht, Netherlands, ⁵Orbis Medical Center, Gastroenterology and Hepatology, Sittard, Netherlands, ⁶Atrium Medical Center, Internal Medicine and Gastroenterology, Heerlen, Netherlands

V. Petito¹, L. Lopetuso¹, E. Stigliano², V. Arena², S. Bibbo¹, A. Amato³, G. Cammarota¹, A. Papa^1,4, A. Sgambato², A. Gasbarrini¹, F. Scaldaferri¹, ¹Catholic University of Sacred Heart, Internal Medicine and Gastroenterology, Rome, Italy, ²Catholic University of Sacred Heart, Pathology, Rome, Italy, ³Catholic University of Sacred Heart, Anesthesiology, Rome, Italy, ⁴Catholic Universisty, Internal Medicine and Gastroenterology Unit, Complesso Integrato Columbus, Rome, Italy

A. Quaglio¹, A. Castilho¹, L. Di Stasi¹, ¹Universidade Estadual Paulista (UNESP), Pharmacology, Botucatu, Brazil

A. Wacrenier*¹, A.-M. Bourgeois², J. Ausseil², C. Szymanski³, H. Thiebault¹, F. Brazier¹, A. Galmiche², E. Nguyen-Khac¹, J.-L. Dupas¹, J.-f. Colombel⁴, M. Fumery¹

¹Amiens University Hospital, Hepatogastroenterology, Amiens, France, ²Amiens University Hospital, Biochimie, Amiens, France, ³Amiens University Hospital, Cardiology, Amiens, France, ⁴Icahn School of Medicine at Mount Sinai Hospital, Gastroenterology, New York, NY, United States

S. Borg-Bartolo¹, J. McLaughlin², C. Ballestrem³, S. Cruickshank¹, ¹University of Manchester, Manchester Immunology Group, Faculty of Life Sciences, Manchester, United Kingdom, ²Salford Royal NHS Foundation Trust, School of Translational Medicine, Manchester, United Kingdom, ³University of Manchester, Wellcome Trust Centre for Cell Matrix Research, Manchester, United Kingdom

J. Wilburn¹, S.P. McKenna¹, J. Twiss¹, M. Ben-L'amri¹, K. Kemp², S. Campbell², ¹Galen Research Ltd, Manchester Science Park, Manchester, United Kingdom, ²Central Manchester University Hospitals NHS Foundation Trust, Gastroenterology, Manchester, United Kingdom

W.K. van Deen*¹, A.B. Ozbay², M. Skup², M.G. van Oijen¹, A. Centeno¹, N. Duran¹, P. Lacey¹, D. Jatulis³, M. Belman³, E. Esrailian¹, D.W. Hommes¹

¹UCLA Center for Inflammatory Bowel Diseases, Division of Digestive Diseases, University of California, Los Angeles, Los Angeles, United States, ²AbbVie, US Immunology, Nort Chicago, United States, ³Anthem Blue Cross, California, Woodland Hills, United States

M. Broekman, H.M. Roelofs, F. Hoentjen, M. Kerstholt, W.H. Peters, G.J. Wanten, D.J. de Jong, Radboud UMC, Gastroenterology & Hepatology, Nijmegen, Netherlands

C.B. Dias¹, L.R. Meirelles², M. Milanski³, M.L.S. Ayrizono⁴, A. Coope³, M. Portovedo³, N. Planell⁵, C.S.R. Coy⁴, L.A. Velloso³, R.F. Leal¹, ¹University of Campinas, Colorectal Surgery Unit, Surgery Department. Cell Signalization Laboratory, Internal Medicine Department, Campinas, Brazil, ²University of Campinas, Pathology Department, Campinas, Brazil, ³University of Campinas, Cell Signalization Laboratory, Internal Medicine Department, Campinas, Brazil, ⁴University of Campinas, Colorectal Surgery Unit, Surgery Department, Campinas, Brazil, ⁵CIBER-EHD, Department of Gastroenterology and Bioinformatics Platform, Barcelona, Spain

S. Riestra¹, R. de Francisco*², M. Arias-Guillén³, C. Saro⁴, M. García-Alvarado⁵, J.M. Duque⁶, L. Blanco², O. Castaño², F. Muñoz⁵, I. Pérez-Martínez², P. Martínez-Camblor⁷, D. Pérez-Hernández⁸

¹Hospital Universitario Central de Asturias , Gastroenterology, Oviedo, Spain, ²Hospital Universitario Central de Asturias, Gastroenterology, Oviedo, Spain, ³Hospital Universitario Central de Asturias, Respiratory, Oviedo, Spain, ⁴Hospital de Cabueñes, Gastroenterology, Gijón, Spain, ⁵Hospital de León, Gastroenterology, León, Spain, ⁶Hospital San Agustín, Gastroenterology, Avilés, Spain, ⁷Hospital Universitario Central de Asturias, Oficina de Investigación Biosanitaria, Oviedo, Spain, ⁸Consejería de Salud, Servicio de Vigilancia Epidemiológica, Oviedo, Spain

E. Gaetani, M. Marcantoni, I. Giarretta, I. Gatto, F. Scaldaferri, F. Del Zompo, L. Laterza, A. Tortora, R. Landi, A. Gasbarrini, R. Pola, Catholic University of Sacred Heart, Internal Medicine and Gastroenterology, Rome, Italy

J. Landy¹, E. Ronde², H. Omar Al-Hassi², E. Mann², S. Peake¹, P.J. Ciclitira³, R.J. Nicholls⁴, S.K. Clark⁵, S. Knight², A.L. Hart¹, ¹St Mark's Hospital, IBD Unit, London, United Kingdom, ²Antigen Presentation Research Group, Imperial College, London, United Kingdom, ³St Thomas' Hospital, Gastroenterology, London, United Kingdom, ⁴Imperial College, Department of Biosurgery and Surgical Technology, London, United Kingdom, ⁵St Mark's Hospital, Colorectal Surgery, London, United Kingdom