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Matrix Metalloproteinase Degraded Biglycan (BGM) and Citrullinated and MMP-degraded Vimentin (VICM) differentiates Crohn's disease from ulcerative colitis.
J.H. Mortensen*1, L. Godskesen2, M.D. Jensen2, L. Klinge2, J. Kjeldsen2, M. Karsdal1, A.-C. Bay-Jensen1, A. Krag2
1Nordic Bioscience, Rheumatology, Herlev, Denmark, 2Odense University Hospital, Gastroenterology , Odense, Denmark
Divergent effects of gut bacteria altered in dysbiosis of inflammatory bowel disease on monocytes and macrophage polarisation
T. Kruis1, A. Batra1, G. Loh2, M. Blaut2, B. Siegmund1, 1Charité Universitätsmedizin Berlin, Abteilung für Gastroenterologie, Infektiologie und Rheumatologie, Berlin, Germany, 2Deutsches Institut für Ernährungsforschung Potsdam-Rehbrücke, Abteilung für Gastrointestinale Mikrobiologie, Potsdam, Germany
S. Shinzaki1, H. Iijima1, T. Inoue1, M. Tsujii1, E. Miyoshi2, T. Takehara1, 1Osaka University, Gastroenterology and Hepatology, Suita, Japan, 2Osaka University, Molecular Biochemistry and Clinical Investigation, Suita, Japan
The relationship between onset days and clinical characteristics of pouchitis after ileal pouch-anal anastomosis in Ulcerative Colitis
Y. Okita*, T. Araki, M. Kawamura, Y. Nagano, S. Kondo, M. Inoue, Y. Toiyama, K. Tanaka, Y. Inoue, K. Uchida, Y. Mohri, M. Kusunoki
Mie University Graduate School of Medicine, Gastrointestinal and Pediatric Surgery, Tsu, Japan
Divalent metal-ion transporter 1 deficiency contributes to the anemia in inflammatory bowel disease
C. Liu, W. Wu, T. Chen, L. Fang, M. Sun, R. Wu, Z. Liu, Shanghai Tenth People's Hospital, Tongji University, Department of Gastroenterology, Shanghai, China
N. O'Shea1, A. Smith1, J. Dunne1, T. Chew1, A. Segal1, 1University College London, Centre of Molecular Medicine, Division of Medicine, London, United Kingdom
Low-grade Dysplasia in Ulcerative Colitis: Risk Factors associated with Progression to High-grade Dysplasia or Colorectal Cancer
C.H.R. Choi*1, A. Ignjatovic Wilson1, M. Rutter2, M. Moorghen1, S. Thomas-Gibson1, J. Warusavitarne1, B. Saunders1, T. Graham3, A. Hart1
1St Mark's Hospital, Department of IBD, Colorectal Surgery and Wolfson Unit of Endoscopy, London, United Kingdom, 2University Hospital of North Tees, Department of Gastroenterology, Stockton-on-Tees, Teesside, United Kingdom, 3Queen Mary University of London, Centre for Tumour Biology, Barts Cancer Institute, London, United Kingdom
Dissecting the role of PPARgamma in intestinal fibrosis: EMT-activator ZEB1 as new molecular target
S. Speca1, V. Flati2, C. Rousseaux3, C. Dubuquoy3, A. Langlois4, L. Dubuquoy1, B. Bertin4, S. Bellinvia5, P. Desreumaux1,6, G. Latella7, 1INSERM, U995, Lille, France, 2University of L'Aquila, Scienze cliniche applicate e biotecnologiche, L'Aquila, Italy, 3Intestinal Biotech Development, Intestinal Biotech Development, Lille, France, 4Université Lille-Nord de France, U995, Lille, France, 5Giuliani Spa, Milan, Italy, 6CHRU Lille, Gastroenterology, Lille, France, 7University of L'Aquila, Medicina clinica, sanità pubblica, scienze della vita e dell'ambiente, L'Aquila, Italy
S. Slevin1, C. Dennedy1, M. Griffin1, L. Egan2, 1National University of Ireland, Galway, REMEDI, Galway, Ireland, 2National University of Ireland, Galway, Department of Pharmacology and Therapeutics, Galway, Ireland
Attributes of anti-TNF treatment that impact on preferences of patients with Crohn's disease candidates for biological treatment (IMPLICA Study)
N. Borruel*1, S. Riestra2, J. Castro3, M. Costi4, L. Rodriguez-San Pedro5, C. Taxonera6, F. Casellas7
1Hospital Vall d´Hebrón, , Digestive, Barcelona. , Spain, 2Hospital Central de Asturias,, Digestive, Oviedo, Spain, 3Hospital Arquitecto Marcide, , Digestive, Ferrol, Spain, 4Abbvie, Health Economics and Market Access, Madrid, Spain, 5Abbvie, Medical and Quality Assurance, Madrid, Spain, 6Hospital Clínico San Carlos, ., Digestive, Madrid. , Spain, 7Hospital Vall d´Hebrón, , Digestive , Barcelona, Spain
Direct smooth muscle stimulatory effect of nitrergic inhibition by L-NMMA on the migrating motor complex modulated by muscarinic and 5-HT3 receptor blockade
M.A. Halim1, S. Boghos1, L. Gillberg1, U. Karlbom2, M. Sundbom2, D.-L. Webb1, P.M. Hellström1, 1Uppsala University, Medical sciences, gastroenterology & hepatology, Uppsala, Sweden, 2Uppsala University, Surgical sciences, surgery, Uppsala, Sweden
M. Principi1, N. De Tullio1, K. Lofano1, M. Pricci1, M.P. Scavo1, G. Piacentino1, A. Contaldo1, V. Neve1, E. Ierardi2, M.C. Comelli3, A. Di Leo1, 1University of Bari, Bari, Italy, 2University of Foggia, Italy, 3CM&D Pharma srl, Padova, Italy