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P077. Proteolytic and oxidative degradation of the polypeptides of the mucous membrane of the colon in patients with ulcerative colitis
P077

The acquisition of cancer stemness by Atoh1 in colitis associated cancer

Authors:

K. Tsuchiya*1, K. Fukushima2, R. Hayashi2, S. Hibiya2, N. Horita2, M. Watanabe2

1Tokyo Medical and Dental University, Advanced Therapeutics for Gastrointestinal Diseases, Tokyo, Japan, 2Tokyo Medical and Dental University, Gastroenterology and Hepatology, Tokyo, Japan

P078.

Effect of methanolic bark extracts of Chrysophyllum albidum on acetic acid-induced colitis in rats

Authors:

A.T. Salami, A.I. Oyelami, T.P. Omayone, E.O. Adewoye, S.B. Olaleye, University of Ibadan, Physiology, Ibadan, Nigeria

P078. Efficacy of human anti-macrophage migration inhibitory factor antibodies in mouse models of inflammatory bowel disease
Authors:

M. Thiele1, E. Magelky2, A. Schinagl1, D. Völkel1, P. Douillard1, H. Ehrlich1, F. Scheiflinger1, R. Kerschbaumer1, C. Terhorst2, 1Baxter Innovations GmbH, Vienna, Austria, 2Beth Israel Deaconess Medical Center, Harvard Medical School, Division of Immunology, United States

P078. Splanchnic haemodynamics and intestinal vascularity in Crohn's disease. An in vivo evaluation using Doppler ultrasound, contrast-enhanced ultrasound and biochemical parameters
P078. The first experience in marked mesenchymal stromal cell in Crohn's disease
P078

Evaluating the efficacy of potential drugs for intestinal fibrosis using precision-cut tissue slices

Authors:

R. Iswandana*, B. Pham, W. van Haaften, D. Oosterhuis, H. Mutsaers, P. Olinga

University of Groningen, Pharmaceutical Technology and Biopharmacy, Groningen, Netherlands

P079.

Effect of enteral nutrition on dendritic cell phenotype in children with Crohn's disease

Authors:

R. Vora1, D. Bernardo1, J. Fell2, H.O. Al-Hassi1, S.C. Knight1, A.L. Hart3, 1Imperial College London, Antigen Presentation Research Group (APRG), London, United Kingdom, 2Chelsea and Westminster Hospital Foundation NHS Trust, Paediatric Gastroenterology, London, United Kingdom, 3St Mark's Hospital, Colorectal Surgery & IBD Unit, London, United Kingdom

P079. Effects of a mixture of amino acids on colonic mucosa healing after experimental colitis
Authors:

X. Liu1, M. Baumont1, J.-C. Marie2, C. Chaumontet1, M. Andriamihaja1, F. Walker2, H. Matsumoto3, D. Tomé1, A.-M. Davila1, F. Blachier1, 1Institut National de la Recherche Agronomique (INRA), AgroParisTech, Centre de Recherche en Nutrition Humaine-Ile de France, UMR 914 Physiologie de la Nutrition et du Comportement Alimentaire, Paris, France, 2Institut National de la Santé et de la Recherche Médicale (INSERM) Université Paris 7 Denis Diderot, U773, Centre de Recherche Biomédicale Bichat Beaujon CRB3, Paris, France, 3Institute for Innovation, Ajinomoto Co. Inc, Frontier Research Laboratory, Kawasaki, Japan

P079. Level changes of serum anti-glycan antibodies in individual Crohn's disease patients over time
P079

Predicting the risk of acute severe colitis (ASC) at diagnosis of Ulcerative Colitis (UC): external validation

Authors:

M. Cesarini*1, 2, G. Collins3, A. Ronnblom4, A. Santos5, 6, D. Sjoberg4, M. Parkes7, S. Keshav2, S. Travis2

1Sapienza, University of Rome, Department of Internal Medicine and Medical Specialties, Rome, Italy, Rome, Italy, 2John Radcliffe Hospital, Translational Gastroenterology Unit, Oxford, United Kingdom, 3University of Oxford, Centre for Statistics in Medicine, Oxford, United Kingdom, 4Uppsala University, Department of Medical Sciences, Uppsala, Sweden, 5Hospital Amato Lusitano, Gastroenterology Unit, Castelo Branco, Portugal, 6Cambridge University hospitals, Gastroenterology Unit, Cambridge, United Kingdom, 7University of Cambridge, Gastroenterology Unit, Cambridge, United Kingdom

P080.

Effect of chondroitin sulphate on pro-inflammatory mediators and disease activity in patients with inflammatory bowel disease (IBD)

Authors:

P.M. Linares1, M. Chaparro1, A. Algaba2, I. Guerra2, M. Román3, I. Moreno Arza3, F. Abad Santos3,4, D. Ochoa3, F. Bermejo2, J.P. Gisbert1, 1Hospital Universitario de La Princesa, IP and CIBERehd, Gastroenterology Unit, Madrid, Spain, 2Hospital Universitario de Fuenlabrada, Gastroenterology Unit, Fuenlabrada, Spain, 3Hospital Universitario de La Princesa and IP, Farmacy Unit, Madrid, Spain, 4CIBERehd, Farmacy Unit, Madrid, Spain

P080. Current European practice in diagnosis and treatment of IBD-associated anaemia
P080. Desensitization of the IGF‑1 receptor signal transduction in rat colon with experimental colitis
P080. Effect of insulin like growth factor-1 on experimental colitis
Authors:

D. Cano-Martínez1, L. Sebastián Monasor1, I.D. Román1, M.D. Fernández-Moreno1, B. Hernández-Breijo1, M.V.T. Lobo2, P. Sanmartín-Salinas1, J.P. Gisbert3, L.G. Guijarro1, 1Universidad de Alcalá de Henares and CIBEREHD, Biochemistry and Molecular Biology, Alcalá de Henares, Spain, 2Universidad de Alcalá de Henares IRYCIS, Cell Biology and Genetics, Alcalá de Henares, Spain, 3Hospital Universitario de la Princesa-IP, Gastroenterology and CIBEREHD, Madrid, Spain

P080

Persistence and sensitivity of colonic biopsies for microscopic colitis in a regional cohort

Authors:

J. Rasmussen1, P.J.H. Engel2, L.K. Munck*3

1Koege University Hospital, Department of Medicine, Koege, Denmark, 2Roskilde University Hospital, Department of Pathology, Roskilde, Denmark, 3University of Copenhagen, Faculty of Health and Medical Sciences, Copenhagen, Denmark

P081.

ER stress leads to epithelial to mesenchymal transition (EMT) in intestinal epithelial cells in a JNK- and Src-dependent manner

Authors:

C. Stanzel, A. Terhalle, M. Scharl, G. Rogler, University Hospital Zurich, Gastroenterology & Hepatology, Zurich, Switzerland

P081. Clinical and phenotypic characteristics of ulcerative colitis at diagnosis according to age: A population-based study
P081. Effect of condroitin sulphate on pro-inflammatory mediators and disease activity in patients with inflammatory bowel disease (IBD)
Authors:

P.M. Linares1, M. Chaparro1, A. Algaba2, M. Román3, I. Moreno Arza3, F. Abad Santos3, D. Ochoa3, F. Bermejo2, J.P. Gisbert1, 1Hospital Universitario de la Princesa-IP, Gastroenterology and CIBEREHD, Madrid, Spain, 2Hospital Universitario de Fuenlabrada, Gastroenterology, Fuenlabrada, Spain, 3Hospital Universitario de la Princesa-IP, Clinical Pharmacology and CIBEREHD, Madrid, Spain

P081. Post surgical recurrence in patients with Crohn's disease: Accuracy of abdominal ultrasonography with oral contrast enhancement performed six months after surgery