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P069. Identification of subgroups of adalimumab-treated patients with Crohn's disease who experience high rates of deep remission
P069

Interleukin 35 and 37 Intestinal Expression and Peripheral Synthesis by Subsets of Regulatory Cells in Patients with Inflammatory Bowel Disease.

Authors:

G. Fonseca Camarillo*1, F.-C. Janette2, Y.F. Jesús Kazuo3

1Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán. México D.F, México., Inflammatory Bowel Disease Clinic. Department of Gastroenterology. , Distrito Federal, Mexico, 2Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán. México D.F, México., Department of Gastroenterology, Mexico City, Mexico, 3Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán. México D.F, México., Inflammatory Bowel Disease Clinic. Department of Gastroenterology., Mexico City, Mexico

P070.

Healing of TNBS-induced colitis in the rat by peptide Hp(2-20)

Authors:

M. Romano1, A.G. Gravina1, A. Federico1, G. D'Argenio2, C. Tuccillo1, A. Miranda1, N. Prevete3, A. De Paulis3, C. Loguercio1, 1Second University of Naples, Gastroenterology Unit, Department of Clinical and Experimental Medicine, Naples, Italy, 2Federico II University of Naples, Gastroenterology Unit, Department of Clinical and Experimental Medicine, Naples, Italy, 3Federico II University of Naples, Clinical Immunology and Allergy Division, Naples, Italy

P070. Activation of the Th9/Th17 pathway in inflammatory bowel disease patients failing anti‑TNF therapy
P070. Economic impact of deep remission in adalimumab-treated patients with Crohn's disease: Results from EXTEND
P070. Genetic polymorphisms of interleukin 15 (IL-15) in patients with ulcerative colitis
Authors:

J. Yamamoto-Furusho1, J. De-Leon-Rendon1, G. Vargas-Alarcon2, 1IBD Clinic, Instituto Nacional de Ciencias Medicas y Nutricion, Gastroenterology, Mexico, Mexico, 2Instituto Nacional de Cardiologia, Molecular Biology, Mexico

P070

Ferrous sulphate but not iron polymaltose complex aggravates local and systemic inflammation and oxidative stress in DSS-induced colitis in rats

Authors:

J.E. Toblli*, G. Cao, M. Angerosa

University of Buenos Aires, School of Medicine, Hospital Alemán, Laboratory of Experimental Medicine, Buenos Aires, Argentina

P071.

G protein-coupled receptor 30 expression in inflammatory bowel disease patients

Authors:

A. Sobolewska1, M. Wlodarczyk1, A. Piechota-Polanczyk2, J. Fichna2, M. Wisniewska-Jarosinska1, 1Medical University of Lodz, Department of Gastroenterology, Lodz, Poland, 2Medical University of Lodz, Department of Biomolecular Chemistry, Lodz, Poland

P071. Alterations in epithelial and dendritic cell tight junction proteins expression in the ileo-anal pouch following ileostomy closure
P071. Are isolated ileal abnormalities a clinically relevant entity? A retrospective study
P071. Gelenterum ameliorates murine colitis while modulating gut microbiota and intestinal mucus layer
Authors:

F. Scaldaferri1, L.R. Lopetuso1, V. Petito1, V. Gerardi1, M. Bilotta2, A. Poscia3, M. Papi4, G. Maolucci5, V. Cufino6, E. Stigliano6, V. Arena6, G. Delogu2, M. Sanguinetti2, M. De Spirito4, A. Sgambato6, A. Gasbarrini1, 1Catholic University of Sacred Hearth, Internal Medicine, Gastroenterology Division, Rome, Italy, 2Catholic University of Sacred Hearth, Istitute of Microbiology, Rome, Italy, 3Catholic University of Sacred Hearth, Insitute of Hygiene, Rome, Italy, 4Catholic University of Sacred Hearth, Istitute of Phisics, Rome, Italy, 5Catholic University of Sacred Hearth, Institute of Phisics, Rome, Italy, 6Catholic University of Sacred Hearth, Institute of Pathology, Rome, Italy

P071

Defining the aims of multi-disciplinary team driven care within an inflammatory bowel disease service provision - Results from a Delphi consensus-building methodology

Authors:

A. Hart*1, N. Sevdalis2, J. Warusavitarne1, J. Green3, C. Edwards4, O. Faiz1

1St Mark's Hospital, Colorectal Surgery & IBD Unit, London, United Kingdom, 2Imperial College London, Surgery and Cancer, London, United Kingdom, 3University College Hospitals, Urology and Cancer, London, United Kingdom, 4Torbay Hospital, Gastroenterology, Torbay, United Kingdom

P072.

GLPG0634, the first selective JAK1 inhibitor, shows strong activity in the mouse DSS-colitis model

Authors:

D. Merciris1, C. Delachaume2, V. De Vriendt3, A.-L. Boutet4, L. Perret1, M.-C. Ceccotti2, S. De Vos3, A. Monjardet4, R. Brys5, R. Galien6, 1Galapagos SASU, Histology, Romainville, France, 2Galapagos SASU, in vivo pharmacology, Romainville, France, 3Galapagos NV, Cell-based assays, Mechelen, Belgium, 4Galapagos SASU, DMPK, Romainville, France, 5Galapagos NV, Inflammation therapeutic area, Mechelen, Belgium, 6Galapagos SASU, Inflammation therapeutic area, Romainville, France

P072. A novel mouse model relates thiopurine hepatic sinusoidal obstructive syndrome to dose-exposure of 6‑thioguanosine nucleotides
P072. Diagnostic medical radiation in inflammatory bowel disease: Primum non-nocere?
P072. Ezrin, LAMC2 and ITG α 6 as possible biomarkers of ulcerative colitis-associated colonic dysplasia
Authors:

J. Bjerrum1, J. Olsen2, G. Rogler3, O. Nielsen1, 1Herlev Hospital, Department of Gastroenterology, Medical Section, Herlev, Denmark, 2Panum, Copenhagen University, Department of Cellular and Molecular Medicine, Copenhagen, Denmark, 3University Hospital Zürich, Division of Gastroenterology and Hepatology, Zürich, Switzerland

P072

Flow cytometric detection of vitamin D receptor changes during vitamin D treatment in Crohn's disease

Authors:

M. Bendix*1, A. Dige1, B. Deleuran2, J.F. Dahlerup1, S.P. Jørgensen3, L.E. Bartels4, T. Harsløf5, L. Husted5, B. Langdahl5, J. Agnholt1

1Aarhus University Hospital, Department of Hepatology and Gastroenterology, Aarhus, Denmark, 2Aarhus University, Institute of Biomedicine, Department of Immunology, Aarhus, Denmark, 3Regional Hospital Horsens, Department of Medicine, Horsens, Denmark, 4Aarhus University Hospital, Department of Rheumatology, Aarhus, Denmark, 5Aarhus University Hospital, Department of Endocrinology and Internal Medicine, Aarhus, Denmark

P073.

Fibrosis does not increase with disease duration in ulcerative colitis

Authors:

J. de Bruyn1,2, S. Meijer3, M. Wildenberg1, G. van den Brink1,2, G. D'Haens2, 1Academic Medical Center, Tytgat Institute for Liver and Intestinal Research, Amsterdam, Netherlands, 2Academic Medical Center, Gastroenterology & Hepatology, Amsterdam, Netherlands, 3Academic Medical Center, Pathology, Amsterdam, Netherlands

P073. A comparative study of clinical, endoscopic and histologic findings in patients with gastrointestinal Behçet's disease and Crohn's disease
P073. ADAMDEC1: A novel molecule in inflammation and bowel disease