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P009.

The long-term therapeutic effect of bone marrow-derived mesenchymal stem cells in a dextran sulfate sodium-induced murine colitis

Authors:

H.J. Lee, H.W. Jang, J.-H. Kwon, K.J. Lee, S.J. Park, S.P. Hong, J.H. Cheon, W.H. Kim, T.I. Kim, Institute of Gastroenterology, Yonsei University College of Medicine, Department of Internal Medicine, Seoul, Korea, Republic of

P009. Prediction of AMG 181 pharmacokinetics and pharmacodynamics in humans
P009. The changes of the NO-ergic system, arginase and oxidative processes in the muscular layer of the colon under the conditions of stress and experimental colitis
Authors:

V. Yemelyanenko1, O. Sklyarov1, 1Danylo Halytsky Lviv National Medical University, Biochemistry, Lviv, Ukraine

P009. Treatment of intestinal fibrosis with tocotrienols in an optimized rat model
P009

Stimulation of Toll-Like Receptor 7 normalises colonic epithelial barrier function during colitis in mice

Authors:

J. Estevez*, V. Martinez

Universitat Autònoma de Barcelona, Cell biology, physiology and immunology, Bellaterra - Barcelona, Spain

P010.

The influence of vitamin D3 for colitis model of rats

Authors:

W. Tang1, Y.-J. Ge2, 1The Second Affiliated Hospital of Soochow University, Gastroenterology, SanXiangLu, Suzhou, 215004, China, 2The second Affiliated Hospital of Soochow University, Gastroenterology, Suzhou, China

P010. Investigation of microRNA regulation by NOD2
P010. The effect of interleukin-1 receptor antagonism in the management of intestinal inflammation; an in vitro and in vivo study
Authors:

K. Arvanitidis1, E. Filidou1, V. Valatas2, E. Kouroumalis2, V. Paspaliaris3, G. Kolios1, 1Faculty of Medicine, Democritus University of Thrace, Laboratory of Pharmacology, Alexandropoulis, Greece, 2Medical Department, University of Crete, Gastroenterology Laboratory, Heraklion, Greece, 3Itis Pharmaceuticals Pty Ltd, Melbourne, Australia

P010. Upregulation of gut homing markers on dendritic cells in the functioning and inflamed ileo-anal pouch
P010

The Gut Microbiome-Immune System Interaction as an Aetiological Factor for Fistulising Perianal Crohn's Disease

Authors:

N.A. Yassin*1, P. Hendy2, C. Horder3, H. Al-Hassi4, T. Ansari5, S. Knight4, P. Sibbons5, R. Phillips6, A. Hart2

1St Mark's Hospital, Colorectal Surgery & IBD Unit, London, United Kingdom, 2St Mark's Hospital, IBD Unit, London, United Kingdom, 3Queen Elizabeth Hospital, Surgery, Birmingham, United Kingdom, 4Imperial College London, Antigen Presentation Research Group, London, United Kingdom, 5Northwick Park Institute of Medical Research, Surgical Research Unit, London, United Kingdom, 6St Mark's Hospital, Colorectal Surgery, London, United Kingdom

P011.

The impact of omentectomy on the severity of colitis and adipocytokine expression

Authors:

S. Yapali1, N. Oruc1, C. Yenisey2, M. Sezak3,4, N.G. Ceri5, O. Ozutemiz1, 1Ege University, School of Medicine, Gastroenterology, Izmir, Turkey, 2Adnan Menderes University, School of Medicine, Biochemistry, Aydin, Turkey, 3Ege Universit, School of Medicine, Pathology, Izmir, Turkey, 4Ege University, School of Medicine, Pathology, Izmir, Turkey, 5Adnan Menderes University, School of Medicine, Anatomy, Aydin, Turkey

P011. Anti-TNF-alpha induces a dysregulated tissue-homing profile on human immune cells in-vitro
P011. Resistance to Fas-apoptosis of peripheral T-cells from Crohn's disease patients depends on the regulation that catalase exerts on the apoptotic pathways
P011. The effect of melatonin treatment on DSS induced colitis and probable mechanism by microarray
Authors:

Y.S. Park1, E.K. Kim2, 1Eulji University, Gastroenterology, Seoul, South Korea, 2Eulji University, Dept of Pathology, Seoul, South Korea

P011

Analysis of Innate-like Lymphocyte Subsets in Ulcerative Colitis

Authors:

K. Haga*1, A. Chiba2, T. Shibuya1, T. Osada1, D. Ishikawa1, T. Kodani1, O. Nomura1, S. Watanabe1, S. Miyake2

1Juntendo University, Department of Gastroenterology, Tokyo, Japan, 2Juntendo University, Department of Immunology, Tokyo, Japan

P012.

The effects of mesenchymal stem cells as a cell therapy in animal model of Crohn's disease

Authors:

B.I. Jang1, W.Y. Jung2, I.H. Song2, K.O. Kim1, C.H. Yang3, G.A. Song4, 1Yeungnam University College of Medicine, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Daegu, Korea, Republic of, 2Yeungnam University College of Medicine, Department of Anatomy, Daegu, Korea, Republic of, 3Dongguk University College of Medicine, Division of gastroenterology and Hepatology, department of Internal Medicine, Kyungju, Korea, Republic of, 4Pusan National University School of Medicine, and Biomedical Research Institute, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Busan, Korea, Republic of

P012. Intrarectal administration of oxygenated perfluorodecalin promotes healing of murine colitis by targeting inflammatory hypoxia
P012. The effects of faecal microbiota transplantation on the innate immune system and epithelial tight junction expression in chronic refractory pouchitis
Authors:

J. Landy1, H. Omar Al-Hassi2, E. Ronde2, E. Mann2, S. Peake1, S. McLaughlin3, Z.L. Perry-Woodford4, P.J. Ciclitira5, R.J. Nicholls6, S.K. Clark7, S. Knight2, A.L. Hart1, 1St Mark's Hospital, IBD Unit, London, United Kingdom, 2Antigen Presentation Research Group, Imperial College, London, United Kingdom, 3Royal Bournemouth and Christchurch NHS Hospitals Trust, Gastroenterology, Bournemouth, United Kingdom, 4St Mark's Hospital, London, United Kingdom, 5St Thomas' Hospital, Gastroenterology, London, United Kingdom, 6Imperial College, Department of Biosurgery and Surgical Technology, London, United Kingdom, 7St Mark's Hospital, Colorectal Surgery, London, United Kingdom

P012. Vidofludimus inhibits IL‑17 and improves hapten-induced colitis in young rats by a unique dual mode of action
P012

Efficacy, toxicity and positive psychological effects drive IBD patient preferences on steroid use

Authors:

A. Baakhtari1, A. McCombie*2, R. Mulder2, J. Falvey3, C. Siegel4, P. Irving5, C. Mulder1, R. Gearry6

1VU University Medical Centre, Gastroenterology and Hepatology, Amsterdam, Netherlands, 2University of Otago, Medicine, Christchurch, New Zealand, 3Christchurch Hospital, Gastroenterology, Christchurch, New Zealand, 4Dartmouth-Hitchcock Medical Center, Gastroenterology and Hepatology, Hanover, New Hampshire, United States, 5Guy’s and St. Thomas Hospital, Gastroenterology, London, United Kingdom, 6University of Otago, Christchurch Hospital, Medicine and Gastroenterology, Christchurch, New Zealand