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DOP044.

Patient education in a 14 month randomized trial fails to improve adherence in ulcerative colitis: Influence of demographic and clinical parameters on non-adherence

Authors:

S. Nikolaus1, S. Schreiber1, B. Siegmund2, B. Bokemeyer3,4, E. Bästlein5, O. Bachmann6, W. Kruis7, German IBD Study Group8, 1University Hospital Schleswig-Holstein, Campus Kiel, 1st Med. Department, Kiel, Germany, 2Charité Universitätsmedizin Berlin, Gastroenterology, Infectious Diseases and Rheumatology, Berlin, Germany, 3Gastroenterology Practice, Minden, Minden, Germany, 4Gastroenterology Practice, Minden, Germany, 5Magen Darm Zentrum Köln, MDZ Köln, Köln, Germany, 6Medizinische Hochschule Hannover, Gastroenterology, Hannover, Germany, 7Evangelisches Krankenhaus Kalk, Gastroenterology, Köln, Germany, 8Charité Universitätsmedizin Berlin, Gastroenterology, Berlin, Germany

DOP044

Presence of anti-MZGP2 IgG and IgA antibodies assessed by 2 different ELISA assays is associated with younger age at onset, stricturing disease behavior, need for surgery and ASCA/anti-OMP PlusTM positivity in Crohn's Disease

Authors:

M. Papp*1, N. Sipeki1, G.L. Norman2, Z. Shums2, D. Roggenbuck3, P. Antal-Szalmas4, G. Veres5, P.L. Lakatos6

1University of Debrecen, Clinical Center, Institute of Internal Medicine, Department of Gastroenterology, Debrecen, Hungary, 2Inova Diagnostics, Inc., San Diego, United States, 3Lausitz University of Applied Sciences, Faculty of Natural Sciences, Senftenberg, Germany, 4University of Debrecen, Clinical Center, Department of Laboratory Medicine, Debrecen, Hungary, 5Semmelweis University, 1st Department of Pediatrics, Budapest, Hungary, 6Semmelweis University, 1st Department of Medicine, Budapest, Hungary

DOP045.

Predicting undesirable disease in newly diagnosed IBD patients – results from the Delta cohort

Authors:

V. Nuij1, G. Fuhler1, C. Looman2, R. Beukers3, R. Ouwendijk4, M. Rijk5, A. van Tilburg6, R. Quispel7, K. Bruin8, T. Tang9, H. Smalbraak10, F. Lindenburg11, L. Peyrin-Biroulet12, C.J. van der Woude1, 1ErasmusMC University Medical Center, Gastroenterology and Hepatology, Rotterdam, Netherlands, 2ErasmusMC University Medical Center, Public Health, Rotterdam, Netherlands, 3Albert Schweitzer Hospital, Gastroenterology and Hepatology, Rotterdam, Netherlands, 4Ikazia Hospital, Gastroenterology and Hepatology, Rotterdam, Netherlands, 5Amphia Hospital, Gastroenterology and Hepatology, Breda, Netherlands, 6Sint Franciscus Gasthuis, Gastroenterology and Hepatology, Rotterdam, Netherlands, 7Reinier de Graaf Gasthuis, Gastroenterology and Hepatology, Rotterdam, Netherlands, 8Tweesteden Hospital, Gastroenterology and Hepatology, Tilburg, Netherlands, 9IJsselland Hospital, Gastroenterology and Hepatology, Capelle aan den IJssel, Netherlands, 10Lievensberg Hospital, Internal Medicine, Bergen op Zoom, Netherlands, 11Franciscus Hospital, Gastroenterology and Hepatology, Roosendaal, Netherlands, 12Nancy University Hospital, Université de Lorraine, Gastroenterology and Hepatology, Vandoeuvre-les-Nancy, France

DOP045

pANCA and ASCA in > 400 children with IBD-unclassified (IBD-U), Crohn's Colitis and Ulcerative Colitis (UC) - a longitudinal report from the Porto pediatric IBD group of ESPGHAN

Authors:

D. Turner*1, F. Cameron2, K.-L. Kolho3, K. Kardowsha-Bochenek4, N.A. Afzal5, S. Paul6, C. Romano7, P. Lionetti8, A.C. Hauer9, C. Martinez-Vinson10, G. Veres11, L. Birimberg-Schwartz1

1Shaare Zedek Medical Center , Pediatric Gastroenterolgoy, Jerusalem, Israel, 2University of Edinburgh, Pediatric Gastroenterolgoy, Edinburgh, United Kingdom, 3University of Helsinki, Pediatric Gastroenterolgoy, Helsinki, Finland, 4Medical University, Warsaw, Pediatric Gastroenterolgoy, Warsaw, Poland, 5University Hospital Southampton, Pediatric Gastroenterolgoy, Southampton, United Kingdom, 6University Hospitals Bristol, Pediatric Gastroenterolgoy, Bristol, United Kingdom, 7University of Messina, Pediatric Gastroenterolgoy, Messina, Italy, 8University of Florence, Meyer Children Hospital, Pediatric Gastroenterolgoy, Florence, Italy, 9University Hospital for Pediatrics and Adolescent Medicine of the Medical University of Graz, Pediatric Gastroenterolgoy, Graz, Austria, 10Department of Pediatric Gastroenterology and Nutrition, Robert Debré Hospital, Pediatric Gastroenterolgoy, Paris, France, 11Semmelweis University, Pediatric Gastroenterolgoy, Budapest, Hungary

DOP046.

A multicenter evaluation of clinical and surgical risk factors for anastomotic leak after restorative procto­colectomy with ileal pouch-anal anastomosis

Authors:

S. Sahami1, C. Buskens1, R. Lindeboom2, T. Young-Fadok3, A. de Buck van Overstraeten4, A. D'Hoore4, W. Bemelman1, 1Academic Medical Center, Surgery, Amsterdam, Netherlands, 2Academic Medical Centre, Divisions of Clinical Methods and Public Health, Amsterdam, Netherlands, 3Mayo Clinic, Surgery, Phoenix, United States, 4University of Leuven, Surgery, Leuven, Belgium

DOP046

Surgery and hospitalization rates during the first year after diagnosis in patients with inflammatory bowel diseases from the 2011 ECCO-EpiCom inception cohort

Authors:

Z. Vegh*1, J. Burisch2, N. Pedersen3, I. Kaimakliotis4, D. Duricova5, K. Kofod Vinding6, K.R. Nielsen7, K.H. Katsanos8, S. Odes9, A. Santini10, P. Munkholm3, P. Lakatos1

1Semmelweis University, 1st Department of Medicine, Budapest, Hungary, 2Hvidovre University Hospital, Gastrounit, Medical section, Hvidovre, Denmark, 3Herlev University Hospital, Digestive Disease Center, Medical Section, Copenhagen, Denmark, 4Nicosia private practice, Nicosia private practice, Nicosia, Cyprus, 5Charles University, IBD Center ISCARE, Prague, Czech Republic, 6Amager Hospital, Department of Medicine, Amager, Denmark, 7The National Hospital of the Faroe Islands, Medical Department, Torshavn, Faroe Islands, 8University of Ioannina, 1st Division of Internal Medicine and Division of Gastroenterology, Faculty of Medicine, Ioannina, Greece, 9Soroka Medical Center and Ben-Gurion University of the Negev, Department of Gastroenterology and Hepatology, Beer Sheva, Israel, 10Careggi Hospital, Gastroenterology Unit, Florence, Italy

DOP047.

Is hospitalization predicting the disease course in UC? Prevalence and predictors of hospitalization and re-hospitalization in ulcerative colitis in a population-based inception cohort between 2000–2012

Authors:

B. Lovasz1, M. Mandel1, P.A. Golovics1, I. Szita2, Z. Vegh1, L. Kiss1, A. Horvath3, T. Pandur2, M. Balogh4, A. Mohas1, B. Szilagyi1, L. Lakatos2, P. Lakatos1, 1Semmelweis University, 1st Department of Medicine, Budapest, Hungary, 2Csolnoky F. Province Hospital, Department of Medicine, Veszprem, Hungary, 3Csolnoky F. Province Hospital, Department of Pediatrics, Veszprem, Hungary, 4Grof Eszterhazy Hospital, Department of Medicine, Papa, Hungary

DOP047

Long Term Outcome of Segmental Resection for Crohn's Colitis: an Observational Study on 200 Patients

Authors:

S. Scaringi*, A. Di Bella, F. Giudici, D. Zambonin, F. Ferdinando, G. Batignani, B. Pesi, P. Bechi

Careggi University Hospital, Surgery and Translational Medicine, Florence, Italy

DOP048.

Is hospitalization predicting the disease course in Crohn's disease? Prevalence and predictors of hospitalization and re-hospitalization in Crohn's disease in a population based inception cohort between 2000–2012

Authors:

P.A. Golovics1, M. Mandel1, B. Lovasz1, Z. Vegh1, I. Szita2, L. Kiss1, M. Balogh3, A. Mohas1, B. Szilagyi1, T. Pandur2, L. Lakatos2, P. Lakatos1, 1Semmelweis University, 1st Department of Medicine, Budapest, Hungary, 2Csolnoky F. Province Hospital, Department of Medicine, Veszprem, Hungary, 3Grof Eszterhazy Hospital, Department of Medicine, Papa, Hungary

DOP048

Predictors of post-operative endoscopic recurrence in Crohn's disease: a prospective study of the REMIND group

Authors:

M. Allez*1, C. Stefanescu2, S. Nancey3, A. Buisson4, P. Desreumaux5, P. Marteau6, M. Fumery7, C. Baudry1, J. Filippi8, H. Sokol9, N. Barnich10, P. Hofman11, X. Treton12, P. Seksik9, REMIND1

1Hopital Saint-Louis, APHP - INSERM - Université Diderot, Gastroenterology, Paris, France, 2Hopital Beaujon, Gastroenterology, Clichy, France, 3CHU Lyon, Gastroenterology, Lyon, France, 4CHU Amiens, Gastroenterology, Paris, France, 5CHU Lille, Gastroenterology, Lille, France, 6Hopital Lariboisiere, Gastroenterology, Paris, France, 7CHU Amiens, Gastroenterology, Amiens, France, 8CH Nice, Gastroenterology, Nice, France, 9Hopital Saint-Antoine, APHP, Gastroenterology, Paris, France, 10CHU Clermont-Ferrand, Bacteriology, Clermont-Ferrand, France, 11CHU Nice, Pathology, Nice, France, 12Hopital Beaujon, APHP, Gastroenterology, Cichy, France

DOP049.

Predicting the individal risk of acute severe colitis at diagnosis

Authors:

M. Cesarini1, G. Collins2, L.M. Wang3, N. Fernandopulle1, C. Corte1, J. Brooks1, S. Keshav1, S. Travis1, 1University of Oxford, Translational Gastroenterology Unit, Oxford, United Kingdom, 2University of Oxford, Centre for Statistics in Medicine, Oxford, United Kingdom, 3University of Oxford, Department of Cellular Pathology, Oxford, United Kingdom

DOP049

Involvement of cell fate pathways in early post-surgical recurrence of Crohn's Disease

Authors:

Y. Zabana*1, 2, J. Manyé2, 3, V. Lorén2, 3, E. Pedrosa2, 3, A. Garcia-Jaraquemada3, M. Piñol4, J. Troya4, J. Lozano5, E. Domènech2, 6, E. Cabré2, 7

1Hospital Universitari Mútua Terrassa, Gastroenterology Department, Terrassa, Spain, 2Centro de Investigación Biomédica en Red sobre enfermedades hepáticas y digestivas, CIBERehd, Madrid, Spain, 3Institut Germans Trias i Pujol, IBD Unit, Gastroenterology Department, Badalona, Spain, 4Hospital Universitari Germans Trias i Pujol, Surgery Department, Badalona, Spain, 5Centro de Investigación Biomédica en Red sobre enfermedades hepáticas y digestivas, CIBERehd, Statistics Platform, Madrid, Spain, 6Hospital Universitari Germans Trias i Pujol, Gastroenterology Department, Badalona, Spain, 7Hospital Universitari Germans Trias i Pujol, IBD Unit, Gastroenterology Department, Badalona, Spain

DOP050.

Mucosal healing in ulcerative colitis: Do Mayo 0 and 1 scores really have the same prognostic value? A prospective observational cohort study

Authors:

M. Barreiro-de Acosta, N. Vallejo, D. de la Iglesia, L. Uribarri, I. Baston, R. Ferreiro, A. Lorenzo, J.E. Dominguez-Muñoz, University Hospital Santiago de Compostela, Gastroenterology, Santiago, Spain

DOP050

Early thiopurine use is associated with a reduced risk of surgery in children and young people with Crohn's disease but not in ulcerative colitis

Authors:

V. Chhaya*1, R. Pollok1, E. Cecil2, V. Subramanian3, V. Curcin4, A. Majeed2, S. Saxena2

1St George's University of London, Gastroenterology, London, United Kingdom, 2Imperial College London, Primary care and Public Health, London, United Kingdom, 3St James' University Hospital, Gastroenterology, Leeds, United Kingdom, 4King's College, Computing, London, United Kingdom

DOP051.

Usefulness of a faecal calprotectin rapid semiquantitative test in predicting relapse in patients with ulcerative colitis in remission

Authors:

E. Garcia-Planella1, M. Manyosa2,3, M. Chaparro4, M. Barreiro-de-Acosta5, B. Beltrán6, E. Ricart7, V. García-Sánchez8, M. Esteve9, M. Piqueras10, F. Bermejo11, A. López-Sanromán12, C. Taxonera12, J. Llaó13, J.P. Gisbert4, E. Cabré3, E. Domènech3, 1Hospital de la Santa Creu i Sant Pau, Gastroenterology, Barcelona, Spain, 2Hospital Universitari Germans Trias i Pujol and CIBERehd, Gastroenterology Unit, Badalona, Spain, 3Hospital Universitari Germans Trias i Pujol, Gastroenterology, Badalona, Spain, 4Hospital La Princesa, Gastroenterology, Madrid, Spain, 5Hospital Universitario de Santiago, Gastroenterology, Santiago de Compostela, Spain, 6IIS Hospital La Fe, Gastroenterology, Valencia, Spain, 7Hospital Clínic, Gastroenterology, Barcelona, Spain, 8Hospital Reina Sofía, Gastroenterology, Córdoba, Spain, 9Hospital Mútua Terrassa, Gastroenterology, Terrassa, Spain, 10Consorci Sanitari Terrassa, Gastroenterology, Terrassa, Spain, 11Hospital de Fuenlabrada, Gastroenterology, Fuenlabrada, Spain, 12Hospital Ramón y Cajal, Gastroenterology, Madrid, Spain, 13Xarxa Hospitalària Althaia, Gastroenterology, Manresa, Spain

DOP051

Receiving corticosteroid therapy is associated with a poor outcome in patients with elderly-onset ulcerative colitis: a population-based study

Authors:

B. Pariente*1, M. Fumery2, H. Sarter3, C. Charpentier4, L. Armengol-Debeir4, L. Dauchet5, E. Laberenne6, H. Coevoet7, L. Peyrin-Biroulet8, C. Gower-Rousseau3, G. Savoye4

1Lille University Hospital, Gastroenterology, Lille, France, 2Amiens University Hospital, Gastroenterology, Amiens, France, 3Lille University Hospital, Epidemiology, Lille, France, 4Rouen University Hospital, Gastroenterology, Rouen, France, 5Lille University Hospital , Public Health, Lille, France, 6Seclin Hospital, Gastroenterology, Seclin, France, 7Private Practice, Gastroenterology, Arras, France, 8Nancy University Hospital, Gastroenterology , Nancy, France

DOP052.

Active smoking, and pre-operative anti-flagellin Fla2 and pANCA antibodies may predict postoperative Crohn's disease recurrence: results from a prospective mono-centric trial

Authors:

M. Noben1, A. de Buck van Overstraeten2, S. Lockton3, G. De Hertogh4, F. Princen3, A. Wolthuis2, G. Van Assche1, S. Vermeire1, S. Singh3, A. D'Hoore2, M. Ferrante1, 1University Hospitals Leuven, Department of Gastroenterology, Leuven, Belgium, 2University Hospitals Leuven, Department of Abdominal Surgery, Leuven, Belgium, 3Prometheus Laboratories, Department of Research and Development, San Diego, United States, 4University Hospitals Leuven, Department of Pathology, Leuven, Belgium

DOP052

Lower long-term colectomy rates with IFX than with CsA treatment in moderate to severe UC

Authors:

N. Duijvis*1, 2, A. ten Hove3, C. Ponsioen3, G. van den Brink3, A. te Velde2, G. D'Haens3, M. Löwenberg3

1Amsterdam Medical Center, Tytgat institute for liver and intestinal research, Amsterdam, Netherlands, 2Academic Medical Center, Tytgat Institute for Liver and Intestinal Research, Amsterdam, Netherlands, 3Academic Medical Center, Inflammatory Bowel Disease Centre, Amsterdam, Netherlands

DOP053.

Clinical significance of C-reactive protein levels in predicting responsiveness to iron therapy in patients with inflammatory bowel disease and iron deficiency anaemia

Authors:

T. Iqbal1, S. Vel2, 1University Hospital Birmingham, Department of Gastroenterology, Birmingham, United Kingdom, 2Vifor Pharma Ltd, Oncology and Gastroenterology, Glattbrugg, Switzerland

DOP053

Risk factors of pouchitis after ileal pouch-anal anastomosis in ulcerative colitis: Multivariate analysis

Authors:

H. Ishii*, K. Hata, T. Nishikawa, T. Tanaka, J. Tanaka, T. Kiyomatsu, K. Kawai, H. Nozawa, S. Kazama, H. Yamaguchi, S. Ishihara, E. Sunami, J. Kitayama, T. Watanabe

The University of Tokyo, Surgical Oncology, Tokyo, Japan