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P671

Pregnancy and IBD, do we provide enough patient education? A British study of 1 324 women

Authors:

I. Carbery, C. Selinger*

St James University Hospital, Gastroenterology, Leeds, United Kingdom

P672

Eosinophilia of the gut: Is it inflammatory bowel disease?

Authors:

S. Chetcuti Zammit*1, J. Gauci2, M. Cachia2, K. Sapiano2, P. Ellul1

1Mater Dei Hospital, Gastroenterology, Msida, Malta, 2Mater Dei Hospital, Medicine, Msida, Malta

P673

A model of inflammatory bowel disease (IBD) population-based registry; incidence of IBD in the Romagna region

Authors:

D. Valpiani1, I. Manzi*1, L. Samperi1, S. Gasperoni2, O. Triossi2, M. Di Marco3, A. De Padova3, L. Solmi3, C. Bernabini4, O. Giuliani5, S. Giorgetti5, F. Falcini5, E. Ricci1

1AUSL Romagna, presidio di Forli’, Gastroenterologia ed Endoscopia Digestiva, Forli’, Italy, 2AUSL Romagna, presidio di Ravenna, Gastroenterologia ed Endoscopia Digestiva, Ravenna, Italy, 3AUSL Romagna, presidio di Rimini, Gastroenterologia ed Endoscopia Digestiva, Rimini, Italy, 4AUSL Romagna, presidio di Cesena, Gastroenterologia ed Endoscopia Digestiva, Cesena, Italy, 5Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori, Registro Tumori della Romagna, Meldola, Italy

P674

Clinical features of thrombosis in patients with Crohn’s disease followed at the Clinical Hospital of the University of São Paulo, Brazil

Authors:

A. Ribas Andrade, L. Leite Barros, M. Azevedo, A. Sipahi, A. Zonetti de Arruda Leite*

University of São Paulo, Medical School, Department of Gastroenterology, São Paulo, Brazil

P675

Clinical characteristics of Crohn’s disease and ulcerative colitis patients who switched from an anti-TNF-α agent or natalizumab to vedolizumab or an alternative anti-TNF-α

Authors:

H. Liang1, S. Manne1, J. Shick1, S. Yu1, G. Fusco1, P. Dolin*2

1Takeda Development Centre Americas, Inc., Deerfield, United States, 2Takeda Development Centre Europe Ltd., London, United Kingdom

P676

Influence of hypoxia on healthy volunteers and patients with inflammatory bowel disease

Authors:

S. Vavricka*1, 2, P. Ruiz-Castro1, L. Biedermann1, M. Madanchi1, S. Scharl1, M. Scharl1, G. Rogler1, J. Zeitz1

1University Hospital Zurich, Department of Gastroenterology and Hepatology, Zurich, Switzerland, 2Triemli Hospital, Division of Gastroenterology and Hepatology, Zurich, Switzerland

P677

Use and predictors of complementary and alternative medicine in patients with inflammatory bowel disease: results of a multicentre study of the Austrian IBD Study Group (ATISG)

Authors:

H. P. Gröchenig*1, C. Dejaco2, G. Eckhard3, T. Feichtenschlager4, T. Haas5, A. Kirchgatterer6, R. Koch7, O. Ludwiczek8, A. Mayer9, W. Miehsler10, P. Papay11, P.-G. Peters12, R. Platzer13, G. Reicht14, P. Steiner15, T. Waldhör16, H. Wenzl17, H. Fuchssteiner18, J. Gartner19, G. Novacek2

1Krankenhaus Barmherzige Brüder, Innere Medizin, St Veit an der Glan, Austria, 2Medizinische Universität Wien, Universitätsklinik für Innere Medizin III, Vienna, Austria, 3Landeskrankenhaus Oberpullendorf, Interne Abteilung, Oberpullendorf, Austria, 4Krankenhaus Rudolfstiftung Wien, IV Medizinische Abteilung, Wien, Austria, 5Darmpraxis Salzburg, Ordination, Salzburg, Austria, 6Klinikum Wels-Grieskirchen, Abteilung für Innere Medizin V, Grieskirchen, Austria, 7Medizinische Universität Innsbruck, Innere Medizin I, Innsbruck, Austria, 8Landeskrankenhaus Hall in Tirol, Innere Medizin, Hall in Tirol, Austria, 9Universitätsklinikum St. Pölten, 2. Medizinische Abteilung, St. Pölten, Austria, 10Krankenhaus Barmherzige Brüder, Innere Medizin, Salzburg, Austria, 11Hartmannspital Wien, Innere Medizin, Wien, Austria, 12Landeskrankenhaus Feldkirch, Abteilung für Innere Medizin, Feldkirch, Austria, 13Landeskrankenhaus Wiener Neustadt, Abteilung für Innere Medizin I, Wiener Neustadt, Austria, 14Krankenhaus Barmherzige Brüder Graz, Abteilung für Innere Medizin, Graz, Austria, 15Klinikum Wels-Grieskirchen, Abteilung für Innere Medizin I, Wels, Austria, 16Medizinische Universität Wien, Abteilung für Epidemiologie, Wien, Austria, 17Medizinische Universität Graz, Abteilung für Gastroenterologie & Hepatologie, Graz, Austria, 18KH Elisabethinen Linz, Innere Medizin IV, Linz, Austria, 19Hanusch Krankenhaus, Innere Medizin, Wien, Austria

P678

Factors associated with voluntary childlessness in women with inflammatory bowel disease

Authors:

C. Selinger*1, J. Ghorayeb2, A. Madill2

1St James University Hospital, Gastroenterology, Leeds, United Kingdom, 2University of Leeds, School of Psychology, Leeds, United Kingdom

P679

Mental health is associated with disease course in a sub-group of inflammatory disease bowel patients with Crohn’s disease and ulcerative colitis: a multicentre observational study by the Osaka Gut Forum

Authors:

M. Araki*1, S. Shinzaki1, H. Iijima1, S. Hiyama1, T. Yamada2, S. Arimitsu3, M. Komori4, N. Shibukawa5, A. Mukai6, S. Nakajima7, K. Kinoshita8, T. Miyagi9, S. Kitamura10, Y. Murayama11, H. Ogawa12, Y. Yasunaga13, M. Oshita14, E. Masuda15, H. Tanimukai16, M. Tsujii1, 4, T. Takehara1

1Osaka University Graduate School of Medicine, Department of Gastroenterology and Hepatology, 2-2 Yamadaoka, Suita, Japan, 2Osaka Medical Centre, National Hospital Organisation, Department of Gastroenterology, 2-1-14, Hoenzaka, Chuo-ku, Osaka, Japan, 3Kinshukai, Infusion Clinic, Osaka, Japan, 4Osaka Rosai Hospital, Department of Gastroenterology, 1179-3, Nagasone-cho, Kita-ku, Sakai, Osaka, Japan, 5NTT-west Hospital, Department of Gastroenterology, 2-6-40, Karasugatsuji, Tennoji-ku, Osaka, Japan, 6Sumitomo Hospital, Department of Gastroenterology, 5-3-20, Nakanoshima, Kita-ku, Osaka, Japan, 7Toyonaka Municipal Hospital, Department of Gastroenterology, 4-14-1, Shibahara-cho, Toyonaka, Osaka, Japan, 8Otemae Hospital, Department of Gastroenterology, 1-5-34, Otemae, Chuo-ku, Osaka, Japan, 9Yao Municipal Hospital, Department of Gastroenterology, 1-3-1, Ryukacho, Yao, Osaka, Japan, 10Sakai City Hospital, Department of Gastroenterology, 1-1-1, Minamiyasui-cho, Sakai-ku, Sakai, Osaka, Japan, 11Itami City Hospital, Department of Gastroenterology, 1–100, Koyaike, Itami, Hyogo, Japan, 12Nishinomiya Municipal Central Hospital, Department of Gastroenterology, 8–24, Hayashida-cho, Nishinomiya, Hyogo, Japan, 13Hyogo Prefectural Nishinomiya Hospital, Department of Gastroenterology, 13–9, Rokutanji-cho, Nishinomiya, Hyogo, Japan, 14Osaka Police Hospital, Department of Gastroenterology, 10–31, Kitayama-cho, Tennoji-ku, Osaka, Japan, 15Osaka Minami Medical Centre, National Hospital Organisation, Department of Gastroenterology, 2-1, Kidohigashimachi, Kawachinagano, Osaka, Japan, 16Graduate School of Medicine and Faculty of Medicine, Kyoto University, Department of Clinical Oncology, Pharmacogenomics, and Palliative Medicine, Kyoto, Japan

P680

Aetiological risk factors for developing paediatric inflammatory bowel disease in a prospective cohort

Authors:

I. Yu*1, E. O’Neill1, R. Stanley1, A. Carey2, 3, S. Kiernan2, M. Hamzawi2, K. Driscoll2, S. Quinn2, A. M. Broderick1, 2, B. Bourke1, 2, 3, T. Rafferty2, 3, S. Hussey1, 2, 3

1University College Dublin, Academic Centre for Paediatric Research, School of Medicine and Medical Science, Dublin, Ireland, 2Our Lady’s Hospital for Sick Children Crumlin, Department of Gastroenterology & Hepatology, Dublin, Ireland, 3Our Lady’s Hospital for Sick Children Crumlin, National Children’s Research Centre, Dublin, Ireland

P681

Long-term outcomes of a cohort of Crohn’s disease patients with idiopathic lymphopenia

Authors:

V. Roales1, C. Alba1, J. L. Mendoza1, D. Olivares1, E. Rey2, C. Taxonera*1

1Hospital Clinico San Carlos, IBD Unit, Madrid, Spain, 2Hospital Clinico San Carlos, Gastroenterology, IdiSSC, Madrid, Spain

P682

Clinical characteristics of Crohn’s disease or ulcerative colitis patients who initiated vedolizumab or an anti-TNF-α as first biologic therapy

Authors:

H. Liang1, S. Manne1, J. Shick1, S. Yu1, G. Fusco1, P. Dolin*2

1Takeda Development Centre Americas, Inc., Deerfield, United States, 2Takeda Development Centre Europe Ltd., London, United Kingdom

P683

Skin lesions in patients with inflammatory bowel disease from southern Brazil: an epidemiologic study

Authors:

H. Amarante*1, G. Reis1, A. Szczypkovski1, G. Quadros1, M. Peretti2, M. Mukai2

1Hospital de Clínicas of Federal University of Parana, Gastroenterology, Curitiba, Brazil, 2Hospital de Clínicas of Federal University of Parana, Dermatology, Curitiba, Brazil

P684

A shift to outpatient expenditures in healthcare costs for inflammatory bowel disease: a population-based study in Korea (2010–2014)

Authors:

C. K. Lee*1, S. Y. Rhee1, H. J. Kim1, S. J. Oh1, C. H. Oh1, W.-M. Lim2

1Kyung Hee University School of Medicine, Internal Medicine, Seoul, South Korea, 2Janssen Korea, Seoul, South Korea

P685

Vitamin D levels in newly diagnosed UC are lower in South Asians than white Europeans: Could this be contributing to the increasing incidence of UC in South Asians?

Authors:

R. Misra*1, U. Selvarajah2, O. Faiz3, J. Burisch4, P. Munkholm4, N. Arebi5

1St Marks Academic Institute, Gastroenterology, London, United Kingdom, 2Imperial College NHS Healthcare Trust, Gastroenterology, London, United Kingdom, 3St Mark’s Academic Institute, Colorectal Surgery & IBD Unit, London, United Kingdom, 4North Zealand University Hospital, Gastroenterology, Frederikssun, Denmark, 5St Marks Academic Institute, Gastroenterology, London, United Kingdom

P686

Characteristics of small bowel cancer associated with Crohn’s disease

Authors:

M. Shinozaki*

The Institute of Medical Science, The University of Tokyo, Department of Surgery, Tokyo, Japan

P687

The effect of inflammatory bowel disease on patients’ caregivers

Authors:

A. Zand*, A. Platt, W. K. Van Deen, D. W. Hommes

UCLA Centre for Inflammatory Bowel Diseases, Division of Digestive Diseases, Los Angeles, California, United States

P688

Is smoking cessation linked to new ulcerative colitis cases?—A retrospective cohort based hypothesis

Authors:

M. Grueber*1, N. Fournier2, L. Biedermann3, S. Vavricka4, A. Schöpfer5, C. Clair Willi6, M. Allez7, A. J. Macpherson8, P. Juillerat9

1Inselspital, Bern, Department of Gastroenterology, Bern, Switzerland, 2CHUV, Statistics, Lausanne, Switzerland, 3Universitätsspital, Gastroenterology, Zürich, Switzerland, 4Stadtspital Triemli, Gastroenterology, Zürich, Switzerland, 5CHUV, Gastroenterology, Lausanne, Switzerland, 6CHUV, PMU, Lausanne, Switzerland, 7Hôpital Saint-Louis, Gastroenterology, Lausanne, France, 8Inselpital, Gastroenterology, Bern, Switzerland, 9Inselspital, Gastroenterology, Bern, Switzerland

P689

An observational study on Crohn’s disease activity pattern and long-term outcomes of management strategies in the routine clinical setting in Greece

Authors:

G. Paspatis*1, S. Potamianos2, K. Triantafyllou3, C. Tzathas4, G. Theocharis5, S. Michopoulos6, E. Akriviadis7, J. Karagiannis8, G. Alexopoulou9, A. Boubougianni9, A. Kouloumenta9, S. Ladas10

1Department of Gastroenterology, Benizelion General Hospital, Heraklion, Greece, 2Department of Gastroenterology, Faculty of Medicine, School of Health Sciences, University of Thessaly, Larissa, Greece, 3Hepatogastroenterology Unit, Second Department of Internal Medicine and Research Institute, Attikon University General Hospital, Medical School, Athens, Greece, 4Gastroenterology Department, Tzaneion General Hospital, Piraeus, Greece, 5Department of Gastroenterology, University Hospital of Patras, Rio/Patra, Greece, 6Department of Gastroenterology, Alexandra University Hospital, Athens, Greece, 7Department of Internal Medicine, General Hospital of Thessaloniki, Hippokratio, Thessaloniki, Greece, 8Gastroenterology Unit, Konstantopoulio Hospital, Athens, Greece, 9MSD, Athens, Greece, 10Department of Medicine & Gastroenterology, Medical School, ‘Laiko’ University General Hospital of Athens, University of Athens, Athens, Greece

P690

Worries of patients with inflammatory bowel disease: an indicator of well-being?—results of survey amongst 1 096 participants in a European bilingual clinical cohort

Authors:

V. Pittet*1, C. Vaucher1, F. Froehlich2, B. Burnand1, P. Michetti3, M. H. Maillard4

1Institute of Social and Preventive Medicine, Healthcare Evaluation Unit, Lausanne, Switzerland, 2University Hospital Basel, Division of Gastroenterology & Hepatology, Basel, Switzerland, 3Clinique La Source-Beaulieu, Crohn and Colitis Centre, Lausanne, Switzerland, 4Lausanne University Hospital, Department of Gastroenterology & Hepatology, Lausanne, Switzerland