E. Domènech*¹, M. Barreiro-de Acosta², A. Gutiérrez³, V. García⁴, M. D. Martín Arranz⁵, L. Cea-Calvo⁶, C. Romero⁶, B. Juliá⁶

¹Hospital Universitari Germans Trias i Pujol and CIBERehd, Gastroenterology Unit, Badalona, Spain, ²Complejo Hospitalario Universitario de Santiago, Gastroenterology Unit, Santiago de Compostela, Spain, ³Hospital General Universitario Alicante, Gastroenterology unit, Alicante, Spain, ⁴Hospital Universitario Reina Sofia, Unidad Clinica de Aparato Digestivo, Cordoba, Spain, ⁵Hospital Universitario La Paz, Gastroenterology Unit, Madrid, Spain, ⁶MSD Spain, Medical Department, Madrid, Spain

M. de Jong*^{1, 2}, D. Roosen¹, A. Peters³, A. Masclee^{1, 2}, V. Verstraeten⁴, A. van Tubergen^{5, 6}, M. Pierik^{1, 2}

¹Maastricht University Medical Centre+, Department of Internal Medicine, division of Gastroenterology and Hepatology, Maastricht, Netherlands, ²Maastricht University Medical Centre+, NUTRIM – School for Nutrition and Translational Research in Metabolism, Maastricht, Netherlands, ³Maastricht University Medical Centre+, Department of Internal Medicine, Maastricht, Netherlands, ⁴Maastricht University Medical Centre+, Department of Dermatology, Maastricht, Netherlands, ⁵Maastricht University Medical Centre+, Department of Internal Medicine, division of Rheumatology, Maastricht, Netherlands, ⁶Maastricht University Medical Centre+, CAPHRI - School for Public Health and Primary Care, Maastricht, Netherlands

C. Chavarría-Herbozo*¹, M. J. Casanova¹, M. Barreiro-de Acosta², M. Chaparro¹, E. Ezquiaga¹, L. Bujanda³, M. Rivero⁴, F. Arguelles-Arias⁵, M.D. Martín-Arranz⁶, M. P. Martínez-Montiel⁷, M. Valls⁸, R. Ferreiro², J. Llao⁹, I. Moraleja-Yudego¹⁰, F. Casellas¹¹, B. Antolín-Melero¹², X. Cortés¹³, R. Plaza¹⁴, J. R. Pineda¹⁵, M. Navarro-Llavat¹⁶, S. García-López¹⁷, P. Robledo-Andrés¹⁸, I. Marín-Jiménez¹⁹, E. Iglesias-Flores²⁰, O. Merino²¹, F. Bermejo²², M. R. Arribas-López²³, J.M. Banales³, B. Castro⁴, L. Castro-Laria⁵, R. Honrubia⁶, P. Almela⁸, J. P. Gisbert¹

¹Hospital Universitario de La Princesa, IIS-IP and CIBERehd, Gastroenterology Unit, Madrid, Spain, ²Hospital Clínico Universitario de Santiago, Gastroenterology Unit, Santiago de Compostela, Spain, ³Hospital de Donostia, Instituto Biodonostia, UPV/EHU and CIBEREHD, Gastroenterology Unit, Guipuzcoa, Spain, ⁴Hospital Universitario Marqués de Valdecilla, Gastroenterology Unit, Santander, Spain, ⁵Hospital Universitario Virgen de La Macarena, Gastroenterology Unit, Sevilla, Spain, ⁶Hospital Universitario La Paz, Gastroenterology Unit, Madrid, Spain, ⁷Hospital Universitario 12 de Octubre, Gastroenterology Unit, Madrid, Spain, ⁸Hospital General Universitario de Castellón, Gastroenterology Unit, Castellón, Spain, ⁹Hospital Sant Joan de Deu, Gastroenterology Unit, Manresa, Spain, ¹⁰Hospital Galdakao, Gastroenterology Unit, Vizcaya, Spain, ¹¹Hospital Universitari Vall d’Hebron, Gastroenterology Unit, Barcelona, Spain, ¹²Hospital Clínico Universitario de Valladolid, Gastroenterology Unit, Valladolid, Spain, ¹³Hospital de Sagunto, Gastroenterology Unit, Valencia, Spain, ¹⁴Hospital Universitario Infanta Leonor, Gastroenterology Unit, Madrid, Spain, ¹⁵Hospital Álvaro Cunqueiro, Gastroenterology Unit, Vigo, Spain, ¹⁶Hospital de Sant Joan Despí Moisès Broggi, Gastroenterology Unit, Barcelona, Spain, ¹⁷Hospital Universitario Miguel Servet, Gastroenterology Unit, Zaragoza, Spain, ¹⁸Hospital Universitario San Pedro Alcántara, Gastroenterology Unit, Cáceres, Spain, ¹⁹Hospital Gregorio Marañón and IiSGM, Gastroenterology Unit, Madrid, Spain, ²⁰Hospital Universitario Reina Sofía, Gastroenterology Unit, Córdoba, Spain, ²¹Hospital Universitario de Cruces, Gastroenterology Unit, Bilbao, Spain, ²²Hospital Universitario de Fuenlabrada, Gastroenterology Unit, Madrid, Spain, ²³Hospital Universitario Infanta Sofía, Gastroenterology Unit, Madrid, Spain

M. L. De Castro*¹, N. Martínez², A. Martín², L. Sanromán¹, M. Figueira¹, V. Hernández¹, J. R. Pineda¹, J. Martínez-Cadilla¹, S. Pereira¹, V. Del Campo³, J.-I. Rodríguez-Prada¹

¹Hospital Alvaro Cunqueiro. Complexo Hospitalario Universitario de Vigo.CHUVI, Gastroenterology, Vigo, Spain, ²Hospital Alvaro Cunqueiro. Complexo Hospitalario Universitario de Vigo.CHUVI, Hospital Pharmacy, Vigo, Spain, ³Hospital Alvaro Cunqueiro. Complexo Hospitalario Universitario de Vigo.CHUVI, Epidemiology, Vigo, Spain

T. Hlavaty*, A. Krajcovicova, I. Sturdik, J. Letkovsky, T. Koller, J. Toth, M. Huorka

Comenius University, Faculty of Medicine and University Hospital Bratislava, Fifth Department of Internal Medicine, Bratislava, Slovakia

T. Hibi*¹, S. Hirohata², H. Kikuchi³, U. Tateishi⁴, N. Sato⁵, K. Ozaki⁵, K. Kondou⁵, Y. Ishigatsubo⁶

¹Kitasato University Kitasato Institute Hospital, Centre for Advanced IBD Research and Treatment, Tokyo, Japan, ²Kitasato University School of Medicine, Department of Rheumatology and Infectious Diseases, Sagamihara, Japan, ³Teikyo University School of Medicine, Department of Internal Medicine, Tokyo, Japan, ⁴Tokyo Medical and Dental University Graduate School of Medicine, Department of Diagnostic Radiology and Nuclear Medicine, Tokyo, Japan, ⁵Mitsubishi Tanabe Pharma Corporation, Osaka, Japan, ⁶Yokohama City University, Yokohama, Japan

A. S. Holdam, P. Bager*, J. F. Dahlerup

Aarhus University Hospital, Department of Hepatology and Gastroenterology, Aarhus, Denmark

T. Taida*, T. Nakagawa, S. Hamanaka, H. Koseki, T. Sakurai, K. Okimoto, K. Saito, D. Maruoka, T. Matsumura, M. Arai, T. Katsuno, O. Yokosuka

Chiba University, Department of Gastroenterology and Nephrology, Chiba, Japan

M. de Jong*^{1, 2}, A. van Tubergen^{3, 4}, A. Peters⁵, A. Masclee^{1, 2}, V. Verstraeten⁶, M. Pierik^{1, 2}

¹Maastricht University Medical Centre+, Department of Internal Medicine, division of Gastroenterology and Hepatology, Maastricht, Netherlands, ²Maastricht University Medical Centre+, NUTRIM – 
School for Nutrition and Translational Research in Metabolism, Maastricht, Netherlands, ³Maastricht University Medical Centre+, Department of Internal Medicine, division of Rheumatology, Maastricht, Netherlands, ⁴Maastricht University Medical Centre+, CAPHRI - School for Public Health and Primary Care, Maastricht, Netherlands, ⁵Maastricht University Medical Centre+, Department of Internal Medicine, Maastricht, Netherlands, ⁶Maastricht University Medical Centre+, Department of Dermatology, Maastricht, Netherlands

M. Halling*¹, J. Kjeldsen¹, T. Knudsen², J. Nielsen³, L. Koch Hansen⁴

¹Odense University Hospital, Department of Gastroenterology, Odense, Denmark, ²Esbjerg Hospital, Dept. of Gastroenterology and Hepatology, Esbjerg, Denmark, ³Odense University Hospital, Department of Clinical Epidemiology, Odense, Denmark, ⁴Vejle Hospital, Dept. of Gastroenterology and Hepatology, Vejle, Denmark

K. Sahnan*¹, A. Askari¹, S. Adegbola¹, P. Tozer¹, R. Phillips¹, A. Hart², O. Faiz¹

¹St Mark’s Hospital, Colorectal Surgery, London, United Kingdom, ²St Mark’s Hospital, IBD/Physiology, London, United Kingdom

T. van den Heuvel*^{1, 2}, S. Jeuring^{1, 2}, M. Zeegers^{3, 4}, D. van Dongen¹, A. Wolters¹, A. Masclee^{1, 2}, M. Romberg-Camps⁵, L. Oostenbrug⁵, M. Pierik^{1, 2}, D. Jonkers^{1, 2}

¹Maastricht University Medical Centre+, Division of Gastroenterology and Hepatology, Maastricht, Netherlands, ²Maastricht University Medical Centre+, Nutrim - School of Nutrition and Translational Research in Metabolism, Maastricht, Netherlands, ³Maastricht University Medical Centre+, Department of Complex Genetics, Maastricht, Netherlands, ⁴Maastricht University Medical Centre+, Caphri - School of Public Health and Primary Care, Maastricht, Netherlands, ⁵Zuyderland Medical Centre, Department of Internal Medicine, Sittard-Geleen-Heerlen, Netherlands

S. Jeuring*^{1, 2}, K. Göttgens³, R. Sturkenboom³, M. Romberg-Camps⁴, L. Oostenbrug⁵, J. Melenhorst³, L. Stassen³, A. Masclee^{1, 2}, D. Jonkers^{1, 2}, M. Pierik^{1, 2}, S. Breukink³

¹Maastricht University Medical Centre, Internal Medicine - Division of Gastroenterology and Hepatology, Maastricht, Netherlands, ²Maastricht University Medical Centre, NUTRIM - School for Nutrition and Translational Research in Metabolism, Maastricht, Netherlands, ³Maastricht University Medical Centre, General Surgery, Maastricht, Netherlands, ⁴Zuyderland Medical Centre, Internal Medicine and Gastroenterology-Hepatology, Sittard-Geleen, Netherlands, ⁵Zuyderland Medical Centre, Internal Medicine and Gastroenterology-Hepatology, Heerlen, Netherlands

m. fumery*¹, B. Pariente², h. sarter³, C. Charpentier⁴, L. Armengol-Debeir⁴, J.-L. Dupas⁵, H. Coevoet⁶, L. Peyrin-biroulet⁷, C. Gower-Rousseau⁸, G. Savoye⁴

¹Amiens University Hospital, Department of Gastroenterology and Hepatology, Amiens, France, ²CHRU Lille, Department of Gastroenterology, Lille, France, ³CHRU Lille, Department of Biostatistics EA 2694, Lille, France, ⁴CHU Rouen, Department of Gastroenterology and Hepatology, Rouen, France, ⁵Amiens University Hospital, Hepatogastroenterology, Amiens, France, ⁶Hopital Privé, Les Bonnettes, Arras, France, ⁷CHU Nancy, Department of Gastroenterology and Hepatology, Vandoeuvre-Lès-Nancy, France, ⁸CHRU Lille, Department of Epidemiology, EPIMAD Registry, Lille, France

K. R. Nielsen*^{1, 2}, J. Olsen¹, G. Andorsdóttir², E. Gislason², J. Burisch³

¹The National Hospital of the Faroe Islands, Medical department, Tórshavn, Faroe Islands, ²Genetic Biobank, Tórshavn, Faroe Islands, ³North Zealand University Hospital, Department of Gastroenterology, Frederikssund, Denmark

L. Godny*¹, N. Maharshak¹, L. Yahav¹, N. Fliss-Isakov², U. Gophna³, H. Tulchinsky⁴, I. Dotan¹

¹Tel Aviv Sourasky Medical Centre, IBD Centre, Department of Gastroenterology and Liver Diseases, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ²Tel Aviv Sourasky Medical Centre, Department of Gastroenterology and Liver Diseases, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ³Tel Aviv University, Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv, Israel, ⁴Tel Aviv Sourasky Medical Centre, Proctology Unit, Department of Surgery, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel

C. K. Lee*¹, S. N. Hong², J. P. Im³, B. D. Ye⁴, J. M. Cha¹, S.-A. Jung⁵, K.-M. Lee⁶, D. I. Park², Y. T. Jeen⁷, Y. S. Park⁸, H. J. Kim¹, Y. J. Kim⁹, T. O. Kim¹⁰, G. S. Seo¹¹, E. S. Kim¹², J. S. Koo⁷, J. S. Kim³, B. I. Jang¹³, J. E. Shin¹⁴, J. W. Kim¹⁵, Y. S. Park¹⁶, J. H. Cheon¹⁷, Y. S. Kim¹⁸, H. S. Kim¹⁹, J. Lee²⁰, J. J. Park¹⁷, G. A. Song²¹, C. S. Eun²², S. J. Shin²³, K. C. Huh²⁴, H.-S. Kim²⁵, C. H. Choi²⁶, H. S. Kim²⁷, Y. Kim²⁷

¹Kyung Hee University School of Medicine, Internal Medicine, Seoul, South Korea, ²Sungkyunkwan University School of Medicine, Seoul, South Korea, ³Seoul National University College of Medicine and Liver Research Institute, Seoul, South Korea, ⁴University of Ulsan College of Medicine, Seoul, South Korea, ⁵Ewha Woman’s University School of Medicine, Seoul, South Korea, ⁶The Catholic University of Korea College of Medicine, Seoul, South Korea, ⁷Korea University College of Medicine, Seoul, South Korea, ⁸Eulji University College of Medicine, Eulji hospital, Seoul, South Korea, ⁹Gachon University Gil Medical Centre, Incheon, South Korea, ¹⁰Inje University College of Medicine, Busan, South Korea, ¹¹Wonkwang University School of Medicine, Iksan, South Korea, ¹²Keimyung University School of Medicine, Daegu, South Korea, ¹³Yeungnam University College of Medicine, Daegu, South Korea, ¹⁴Dankook University College of Medicine, Cheonan, South Korea, ¹⁵Seoul National University Boramae Hospital, Seoul, South Korea, ¹⁶Seoul National University Bundang Hospital, Bundang, South Korea, ¹⁷Yonsei University College of Medicine, Seoul, South Korea, ¹⁸Inje University College of Medicine, Seoul, South Korea, ¹⁹Chonnam National University Medical School, Gwangju, South Korea, ²⁰Chosun University College of Medicine, Gwangju, South Korea, ²¹Pusan National University School of Medicine and Biomedical Research Institute, Busan, South Korea, ²²Hanyang University Guri Hospital, Guri, South Korea, ²³Ajou University School of Medicine, Suwon, South Korea, ²⁴Konyang University College of Medicine, Daejeon, South Korea, ²⁵Yonsei University Wonju College of Medicine, Wonju, South Korea, ²⁶Chung-Ang University College of Medicine, Seoul, South Korea, ²⁷Janssen Korea, Medical affairs, Seoul, South Korea

Z. Vegh*¹, J. Burisch², I. Kaimakliotis³, D. Duricova⁴, K. Carlsen², K. R. Nielsen⁵, D. K. Christodoulou⁶, L. Lakatos⁷, S. Odes⁸, R. D’Incà⁹, G. Kiudelis¹⁰, S. Turcan¹¹, F. Magro^{12, 13, 14}, A. Goldis¹⁵, V. Hernandez¹⁶, S. Bell¹⁷, E. Langholz¹⁸, P. Munkholm², P. Lakatos¹

¹Semmelweis University, First Department of Medicine, Budapest, Hungary, ²North Zealand Hospital, University of Copenhagen, Gastro Unit, Medical Section, Copenhagen, Denmark, ³Nicosia private practice, Nicosia private practice, Nicosia, Cyprus, ⁴Charles University, IBD Centre ISCARE, Prague, Czech Republic, ⁵The National Hospital of the Faroe Islands, Medical Department, Torshavn, Faroe Islands, ⁶Faculty of Medicine, University of Ioannina, First Division of Internal Medicine and Division of Gastroenterology, Ioannina, Greece, ⁷Csolnoky F. Province Hospital, Department of Medicine, Veszprem, Hungary, ⁸Soroka Medical Centre and Ben-Gurion University of the Negev, Department of Gastroenterology and Hepatology, Beer Sheva, Israel, ⁹Università di Padova, U. O. Gastroenterologia, Azienda Ospedaliera, Padova, Italy, ¹⁰Lithuanian University of Health Sciences, Institute for Digestive Research, Kaunas, Lithuania, ¹¹State University of Medicine and Pharmacy, Department of Gastroenterology, Chisinau, Moldova, Republic of, ¹²Hospital de São João, Department of Gastroenterology, Porto, Portugal, ¹³Oporto Medical School, Department of Pharmacology and Therapeutics, Porto, Portugal, ¹⁴University of Porto, 8 MedInUP - Centre for Drug Discovery and Innovative Medicines, Porto, Portugal, ¹⁵University of Medicine ‘Victor Babes’, Clinic of Gastroenterology, Timisoara, Romania, ¹⁶Complexo Hospitalario Universitario de Vigo, Gastroenterology Department, Vigo, Spain, ¹⁷St Vincent’s Hospital, Department of Gastroenterology, Melbourne, Victoria, Australia, ¹⁸Herlev and Gentofte Hospital, Department C, Gastroenterology Section, Hellerup, Denmark

C. Hopkins*¹, C. Moulton²

¹Berkshire Healthcare NHS Foundation Trust, Prospect Park Hospital, Reading, United Kingdom, ²Institute of Psychiatry, Psychology & Neuroscience, King’s College London, London, United Kingdom

H.-S. Lee*¹, J. W. Choe¹, H. J. Lee¹, K. Chang², G.-U. Kim², S. W. Hwang², S. H. Park², D.-H. Yang², K.-J. Kim², B. D. Ye², J.-S. Byeon², S.-J. Myung², S.-K. Yang²

¹Asan Medical Centre, University of Ulsan College of Medicine, Health Screening and Promotion Centre, Seoul, South Korea, ²Asan Medical Centre, University of Ulsan College of Medicine, Department of Gastroenterology, Seoul, South Korea