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P431

Transabdominal ultrasonography to assess intestinal wall thickness and vascularity appears to predict therapeutic effects of steroid treatment in moderate-to-severe ulcerative colitis patients

Authors:

T. Ogashiwa*1, M. Murakami1, S. Tsuda1, M. Nishio1, Y. Kogure1, K. Kasahara1, K. Hirai2, Y. Fukuno2, M. Jin2, A. Hanzawa2, H. Yonezawa2, K. Numata3, H. Kimura1, R. Kunisaki1

1Yokohama City University Medical Centre, Inflammatory Bowel Disease Centre, Yokohama, Japan, 2Yokohama City University Medical Centre, Department of Laboratory Medicine and Clinical Investigation, Yokohama, Japan, 3Yokohama City University Medical Centre, Gastroenterology Centre, Yokohama, Japan

P432

Patient perspectives on biosimilars: a European Federation of Crohn’s and Colitis Associations survey

Authors:

L. Peyrin-Biroulet*1, S. Lönnfors2, S. Danese3, X. Roblin4, L. Avedano5, M. Greco5

1University Hospital of Nancy, Department of Gastroenterology, Nancy, France, 2European Federation of Crohn’s and Ulcerative Colitis Associations, Medical Writer, Brussels, Belgium, 3Humanitas University, Department of Gastroenterology, Milan, Italy, 4Saint-Étienne University Hospital, Gastroenterology and Hepatology, Saint-Étienne, France, 5European Federation of Crohn’s and Ulcerative Colitis Associations, Brussels, Belgium

P433

Canadian patient and caregiver perspectives on subsequent entry biologics / biosimilars for inflammatory bowel disease

Authors:

G. Attara*1, R. Bailey2, B. Bressler3, J. Marshall4, R. Panaccione5, G. Aumais6

1Gastrointestinal Society, Vancouver, Canada, 2University of Alberta, Zeidler Ledcor Centre, Department of Medicine, Division of Gastroenterology, Edmonton, Canada, 3University of British Columbia, Medicine, Division of Gastroenterology, St. Paul’s Hospital, Vancouver, Canada, 4McMaster University Medical Centre, Department of Gastroenterology, Hamilton, Canada, 5University of Calgary, Department of Gastroenterology, Foothills Medical Centre, Calgary, Canada, 6CHUM Centre Hospitalier de l’Université de Montréal, Hôpital Maisonneuve-Rosemont, Medicine, Montréal, Canada

P434

Close rectal versus total mesorectal excision in patients with inflammatory bowel disease undergoing proctocolectomy or completion proctectomy

Authors:

J. de Groof*, O. van Ruler, P. Tanis, W. Bemelman, C. Buskens

Academic Medical Centre, Surgery, Amsterdam, Netherlands

P435

Liver injury associated with anti-tumour necrosis factor therapy in paediatric irritable bowel disease patients

Authors:

A. Ricciuto*, B. M. Kamath, T. Walters, P. Church, S. C. Ling, K. Frost, A. Griffiths

Hospital for Sick Children, Division of Gastroenterology, Hepatology and Nutrition, Toronto, Canada

P436

Adalimumab dose escalation is effective and well tolerated in Crohn’s disease patients with secondary loss of response to adalimumab

Authors:

N. Duveau*, M. Nachury, M. Boualit, R. Gerard, J. Branche, V. Maunoury, P. Desreumaux, B. Pariente

CHU de Lille, Department of Gastroenterology, Lille, France

P437

Confidence, acceptance, and friendship: the 3 winners at Camp Purple Live 2015

Authors:

A. McCombie*1, 2, R. Gearry3, R. Lopez4, S. Lönnfors5, A. Day4

1University of Otago, Department of Surgery, Christchurch, New Zealand, 2University of Otago, Department of Medicine, Dunedin, New Zealand, 3University of Otago, Department of Medicine, Christchurch, New Zealand, 4University of Otago, Department of Paediatrics, Christchurch, New Zealand, 5European Federation of Crohn’s and Ulcerative Colitis Associations, Medical Writing, Brussels, Belgium

P438

The inflammatory bowel disease disability index applied to ileal pouch anal anastomoses in New Zealand

Authors:

Y. Lee1, A. McCombie*1, 2, R. Gearry3, F. Frizelle1, J. Williman4, R. Leong5, T. Eglinton1

1University of Otago, Department of Surgery, Christchurch, New Zealand, 2University of Otago, Department of Medicine, Dunedin, New Zealand, 3University of Otago, Department of Medicine, Christchurch, New Zealand, 4University of Otago, Christchurch, Department of Population Health, Christchurch, New Zealand, 5University of New South Wales, Medicine, Sydney, Australia

P439

Effectiveness of a training programme on motivational interviewing skills applied to inflammatory bowel disease management

Authors:

M. Daperno*1, F. Mocciaro2, F. Caprioli3, M. Fantini4, S. Leone5, M. Comberlato6, V. Quercia7

1AO Ordine Mauriziano, Gastroenterology Unit, Torino, Italy, 2ARNAS Ospedale Civico, Gastroenterology Unit, Palermo, Italy, 3IRCCS Ospedale Maggiore, Gastroenterology Unit, Milano, Italy, 4Tor Vergata University, Gastroenterology Department, Roma, Italy, 5EFFCA and AMICI Onlus, Palermo, Italy, 6Bolzano Central Hospital, Department of Gastroenterology, Bolzano, Italy, 7Salesian University Institute, Venezia, Italy

P440

Staged surgical management of complicated ileo-colonic Crohn’s Disease

Authors:

A. P. Mishreki*, F. G. Bergin

Royal Victoria Infirmary, Colorectal Surgery, Newcastle Upon Tyne, United Kingdom

P441

Conjoint analysis for quantification of inflammatory bowel disease patients’ preferences for outcome metrics

Authors:

W. K. van Deen*1, D. Nguyen1, N. Duran1, E. Kane1, M. G. van Oijen2, D.W. Hommes1

1UCLA Centre for Inflammatory Bowel Diseases, Division of Digestive Diseases, University of California, Los Angeles, California, United States, 2Academic Medical Centre, Amsterdam, Department of Medical Oncology, Amsterdam, Netherlands

P442

Evaluation of safety and efficacy of laparoscopic surgery for ulcerative colitis

Authors:

M. Yamamoto*, K. Kurachi, T. Harada

Hamamatsu University School of Medicine, Second Department of Surgery, Hamamatsu, Japan

P443

National treatment strategy in inflammatory bowel diseases in Hungary: results from the National Health Insurance Fund Prescription Database

Authors:

Z. Kurti*1, L. Gonczi1, P. A. Golovics1, B. Lovasz1, P. Fadgyas-Freyler2, J. Gimesi-Orszagh2, G. B. Korponai2, Z. Vegh1, P. Lakatos1

1Semmelweis University, First Department of Medicine, Budapest, Hungary, 2National Health Insurance Fund (OEP), Strategic Analysis Department, Budapest, Hungary

P444

High-dose intravenous iron isomaltoside infusion is not associated with an increase in intact fibroblast growth factor 23 (iFGF23) in patients with inflammatory bowel disease

Authors:

J. F. Dahlerup*1, S. Lindgren2

1Aarhus University Hospital, Department of Hepatology and Gastroenterology, Aarhus, Denmark, 2Lund University, University Hospital MAS, Department of Gastroenterology, Malmö, Sweden

P445

Early outcomes for adolescent inflammatory bowel disease patients treated in a transition clinic

Authors:

I. Avni-Biron1, G. Fraser*1, Y. Rosenbach2, R. Shamir2, A. Assa2, L. Lichtenstein1, O. Ben-Bassat1

1Rabin Medical Centre and University of Tel Aviv, Gastroenterology, Petach Tikva, Israel, 2Schneider Children’s Medical Centre, University of Tel Aviv, Paediatric Gastroenterology, Petach Tikva, Israel

P446

Effects of CYP3A5 genotype on efficacy and safety of tacrolimus in refractory ulcerative colitis: experience from a tertiary referral centre

Authors:

E. Saito*, T. Kobayashi, M. Nakano, T. Toyonaga, S. Kuronuma, O. Takeuchi, H. Serizawa, N. Watanabe, T. Hibi

Kitasato University Kitasato Institute Hospital, Centre for Advanced IBD Research and Treatment, Tokyo, Japan

P447

Seasonal variations in Vitamin D concentrations in a single-centre inflammatory bowel disease series

Authors:

P. Vernia*, G. Burrelli Scotti, M. T. Afferri, V. Vaiarello

Sapienza - University of Rome, Gastroenterologia A, Rome, Italy

P448

IBD nurse in patients’ health status assessment: data from a pilot study comparing ability of IBD nurse and gastroenterologist in using IBD clinical scores

Authors:

F. Mocciaro*1, R. Di Mitri1, G. M. Pecoraro1, D. Scimeca2, G. Russo1, F. Bossa2, V. Costanza1, D. Varvara2, M. A. Profita1, G. Profeta1, G. Martino2

1ARNAS Civico-Di Cristina-Benfratelli Hospital, Gastroenterology and Endoscopy Unit, Palermo, Italy, 2Casa Sollievo della Sofferenza Hospital, IRCCS, Division of Gastroenterology, San Giovanni Rotondo (FG), Italy

P449

Efficacy and safety of switching between originator and biosimilar infliximab in patients with inflammatory bowel disease in practical clinic: results to 6 months

Authors:

L. Díaz Hernández*1, G. E. Rodríguez González1, M. Vela González1, C. A. Tardillo Marín1, C. Y. Rodríguez Díaz1, L. Arranz Hernández1, J. A. Montero Delgado2, M. San Juan Acosta1, F. Pérez Hernández1

1Hospital Universitario Ntra. Sra. Candelaria, Gastroenterology, Santa Cruz de Tenerife, Spain, 2Hospital Universitario Ntra. Sra. Candelaria, Pharmacology, Santa Cruz de Tenerife, Spain

P450

A gender comparison of the association between coping strategies and perceived social support in Crohn’s disease patients

Authors:

O. Sarid1, V. Slomin-Nevo1, D. Greenberg2, M. Friger3, D. Schwartz4, H. Vardi2, R. Sergienko3, E. Chernin3, S. Odes*5

1Ben-Gurion University of the Negev, Social Work, Beer Sheva, Israel, 2Ben-Gurion University of the Negev, Health Systems Management, Beer Sheva, Israel, 3Ben-Gurion University of the Negev, Public Health, Beer Sheva, Israel, 4Soroka University Hospital, Gastroenterology, Beer Sheva, Israel, 5Ben-Gurion University of the Negev, Gastroenterology, Beer Sheva, Israel