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P661. Clinical characteristics of inflammatory bowel disease in elderly patients
Authors:

J. Cadilla1, R. Ferreiro2, V. Ollero3, P. Vega4, A. Fernandez5, L. Sanromán1, E. Castro6, S. Soto4, J.R. Pineda1, A. Lorenzo2, A. Echarri3, V. Hernandez1, D. Carpio7, S. Pereira1, J. Castro3, M. Barreiro-de Acosta2, 1CHUVI, Spain, 2University Hospital, Gastroenterology, Santiago, Spain, 3Arquitecto Marcide, Ferrol, Spain, 4CHOU, Spain, 5Povisa, Spain, 6Hospital Lucus Augusti, Lugo, Spain, 7CHOP, Spain

P661

Different phenotypical characteristics in Romanian IBD patients with rural vs. urban residence: Results of a nationwide multicentric cohort

Authors:

R. Iacob*1, R. Vadan1, I.E. Csiki1, L. Gheorghe1, C. Gheorghe1, C. Cijevschi2, A. Trifan2, D. Dobru3, M. Tantau4, A. Goldis5, G. Constantinescu6, M. Diculescu1

1Fundeni Clinical Institute, Digestive Diseases and Liver Transplantation Center, Bucharest, Romania, 2Gastroenterology and Hepatology Institute , Gastroenterology, Iasi, Romania, 3Municipal Hospital Targu Mures, Gastroenterology, Targu Mures, Romania, 43rd Medical Clinic Cluj-Napoca, Gastroenterology, Cluj-Napoca, Romania, 5District Hospital, Gastroenterology, Timisoara, Romania, 6Floreasca Emergency Hospital, Gastroenterology, Bucharest, Romania

P662.

BAX, a novel susceptibility gene for Crohn's disease

Authors:

A. Fernandez1,2, R. Gonzalez3, V. Prieto1, J. Fernandez3, J. Martin3,4, M. San Maximo3,4, A. Alvarez1, C. Piñero1, Y. Jamanca1, J. Umaña1, A. Velasco1, A. Rodriguez1, 1Hospital Clínico de Salamanca, Gastroenterology, Salamanca, Spain, 2Salamanca, Gastroenterology, Salamanca, Spain, 3University of Salamanca, Medicine, Salamanca, Spain, 4University of Salamanca, Statistics, Salamanca, Spain

P662. Bone disease in male veterans with ulcerative colitis: 10-year nationwide study
Authors:

N. Khan1, A. Abbas2, A. Khan3, 1Southeast Louisiana Veterans Health Care System, Gastroenterology, New Orleans, United States, 2Tulane University, Gastroenterology, New Orleans, United States, 3Tulane University, Endocrinology, New Orleans, United States

P662

Pain in IBD patients: very frequent and frequently insufficiently taken into account

Authors:

J. Zeitz*1, G. Rogler1, S. Müller-Mottet2, L. Biedermann1, N. Fournier3, P. Frei4, V. Pittet3, M. Fried1, S. Vavricka5

1University Hospital Zurich, Division of Gastroenterology & Hepatology, Zurich, Switzerland, 2University Hospital Zurich, Division of Pulmonology, Zurich, Switzerland, 3University of Lausanne, Institute of Social and Preventive Medicine, Lausanne, Switzerland, 4Seespital Horgen, Division of Gastroenterology, Horgen, Switzerland, 5Triemli Hospital, Division of Gastroenterology and Hepatology, Zurich, Switzerland

P663.

Association of HIF1α pathway genes with relevant clinical subphenotypes in inflammatory bowel disease (IBD)

Authors:

P.M. Linares1, M.E. Fernández-Contreras1, M. Chaparro1, A. Juliá2, R. Tortosa2, S. Marsal2, J.P. Gisbert1, 1Hospital Universitario de La Princesa, IP and CIBERehd, Gastroenterology Unit, Madrid, Spain, 2Vall d'Hebron Hospital Research Institute, Rheumatology Research Group, Barcelona, Spain

P663. A nation-wide registry of paediatric inflammatory bowel disease: improvement of diagnostic workup and Paris Classification
Authors:

K. Muller1, Hungarian Pediatric IBD2, M. Papp3, P. Lakatos4, G. Veres1, 1Semmelweis University, Ist Dept. of Pediatrics, Budapest, Hungary, 2Hungarian Society of Pediatric Gastroenterology, Hungary, 3University of Debrecen, 2nd Dept. of Medicine, Debrecen, Hungary, 4Semmelweis University, Ist Dept. of Medicine, Budapest, Hungary

P663

Association of sleep quality and mucosal activity in IBD patients in clinical remission

Authors:

G. Michalopoulos*, S. Vrakas, V. Ntouli, K. Makris, S. Lamprinakos, C. Tzathas

Tzaneio General Hospital, Department of Gastroenterology, Piraeus, Greece

P664.

Association between genetic markers related to tight junctions and inflammatory bowel disease

Authors:

E. Norén1,2, S. Almer3,4, J. Söderman1, 1Ryhov County Hospital, Division of Medical Diagnostics, Jönköping, Sweden, 2Linköping University, Department of Clinical and Experimental Medicine, Linköping, Sweden, 3Karolinska Institutet, Department of medicine, Stockholm, Sweden, 4Karolinska University Hospital, GastroCentrum, Stockholm, Sweden

P664. Asthma prevalence in patients with inflammatory bowel disease
Authors:

G. Sanchez-Sindin1, M. Barreiro-de Acosta2, M. Iglesias-Rey2, N. García Couceiro3, R. Ferreiro2, A. Lorenzo2, L. Valdes3, J.E. Dominguez-Munoz2, F.J. González-Barcala3, 1Hospital do Salnes, Emergency Department, Vilagarcia, Spain, 2University Hospital, Gastroenterology, Santiago, Spain, 3University Hospital, Respiratory, Santiago, Spain

P664

Use of smartphones by UC patients: A vehicle for communication and education

Authors:

R. Hofmann*1, X. Guillaume2

1Tillotts Pharma, Medical Affairs, Rheinfelden, Switzerland, 2Kantar Health , Research, Montrouge, France

P665.

A genome-wide association study identifies DSE-FAM26F as a risk locus for ulcerative colitis

Authors:

E. Domènech1, A. Juliá2, M. Chaparro3, V. García-Sánchez4, F. Gomollón5, J. Panés6, M. Mañosa7, M. Barreiro-de Acosta8, A. Gutiérrez9, E. García-Planella10, P. Nos11, F. Muñoz12, M. Esteve13, J.L. Mendoza14, M. Vera15, L. Marquez16, R. Tortosa2, M. López-Lasanta2, A. Alonso2, J.L. Gelpí17,18, A. García-Montero19, J. Bertanpetit20, D. Absher21, R. Myers21, S. Marsal2, J.P. Gisbert3, 1Hospital Universitari Germans Trias i Pujol and CIBERehd, Gastroenterology Unit, Badalona, Spain, 2Vall d'Hebron Hospital Research Institute, Rheumatology Research Group, Barcelona, Spain, 3Hospital Universitario de La Princesa, IP and CIBERehd, Gastroenterology Unit, Madrid, Spain, 4Hospital Universitario Reina Sofía, Gastroenterology Unit, Córdoba, Spain, 5Hospital Clínico Universitario and CIBERehd, Gastroenterology Unit, Zaragoza, Spain, 6Hospital Clinic de Barcelona, IDIBAPS and CIBERehd, Gastroenterology Unit, Barcelona, Spain, 7Hospital Universitari Germans Trias i Pujol and CIBERehd, Gastroenterology Unit, Barcelona, Spain, 8Hospital Clínico Universitario, Gastroenterology Unit, Santiago de Compostela, Spain, 9Hospital General de Alicante and CIBERehd, Gastroenterology Unit, Alicante, Spain, 10Hospital de la Santa Creu i Sant Pau, Gastroenterology Unit, Barcelona, Spain, 11Hospital La Fe and CIBERehd, Gastroenterology Unit, Valencia, Spain, 12Complejo Hospitalario de León, Gastroenterology Unit, León, Spain, 13Hospital Universitari Mutua de Terrasa, Gastroenterology Unit, Barcelona, Spain, 14Hospital Clínico San Carlos, Gastroenterology Unit, Madrid, Spain, 15Hospital Universitario Puerta de Hierro, Gastroenterology Unit, Madrid, Spain, 16IMIM. Hospital del Mar Medical Research Institute. Pompeu Fabra University, Gastroenterology Unit, Barcelona, Spain, 17National Institute of Bioinformatics, Life Sciences, Barcelona Supercomputing Centre, Barcelona, Spain, 18University of Barcelona, Biochemistry and Molecular Biology, Barcelona, Spain, 19University of Salamanca, Banco Nacional de ADN Carlos III, Salamanca, Spain, 20Universitat Pompeu Fabra, Nacional Genotyping Centre (CeGen), Barcelona, Spain, 21Hudson Alpha Institute for Biotechnology, Alabama, United States

P665. Association of drugs and autoimmune diseases in patients diagnosed with microscopic colitis
Authors:

J. Martínez Cadilla1, P. Estevez Boullosa1, D. Carpio2, A. Carmona3, R. Fernandez4, A. Tardio4, S. Pereira1, M.L. De Castro1, D. Martínez Ares1, A. Fernandez Villaverde3, 1C.H.U.V.I, Gastroenterology, Vigo, Spain, 2C.H. Pontevedra, Gastroenterology, Pontevedra, Spain, 3Hospital POVISA, Gastroenterology, Vigo, Spain, 4C.H.U.V.I, Anatomic Pathologic, Vigo, Spain

P665

Regional differences in health care of patients with IBD in Germany

Authors:

A. Lange*1, A. Prenzler1, O. Bachmann2, R. Linder3, S. Neubauer1, J. Zeilder1, M.P. Manns2, J.-M. Graf von der Schulenburg1

1Leibniz University Hanover, Center for Health Economics Research Hannover (CHERH), Hannover, Germany, 2Hannover Medical School, Department of Gastroenterology, Hepatology, and Endocrinology, Hannover, Germany, 3Scientific Institute of TK for Benefit and Efficiency in Health Care (WINEG), Scientific Institute of TK for Benefit and Efficiency in Health Care (WINEG), Hamburg, Germany

P666.

Type 1 pili and long polar fimbriae are essential for induction of host–microbiota mutualism by adherent-invasive Escherichia coli, even in the presence of competing intestinal microbes

Authors:

E. Vazeille1, M.L. Balmer2, B. Chassaing1, S. Stefan Müller2, T. Thomas Schaffer2, E. Slack3, S. Pfister4, M.B. Geuking5, D. Lottaz2, A.J. Macpherson2, S. Hapfelmeier3, K.D. McCoy2, A. Darfeuille-Michaud1, E. Vazeille1, 1M2iSH UMR 1071 Inserm/Université d'Auvergne USC INRA 2018, Centre Biomédical de Recherche et Valorisation, Clermont-Ferrand, France, 2University Bern, Maurice E Müller Laboratories, Universitätsklinik für Viszerale Chirurgie und Medizin, Inselspital, Bern, Switzerland, 3Institute of Microbiology, D-BIOL, ETH Zürich, Zürich, Switzerland, 4University Bern, Institute for Infectious Diseases, Bern, Switzerland, 5University of Bern, Department Klinische Forschung, Bern, Switzerland

P666. A 7 years study on epidemiologic aspects of inflammatory bowel disease in the north east of Italy
Authors:

T. Slongo1, R. Marcello1, F. Ferrara1, G. Battistella2, H. Heras Salvat1, G. Guarnieri1, N. Dal Bò1, S. Loperfido1, A. Caroli1, A. Schiavinato1, A. Furlanetto3, A.P. Dei Tos3, F. Di Mario1, 1Gastroenterology Unit, Treviso General Hospital, Department of Internal Medicine, Treviso, Italy, 2Treviso General Hospital, Department of Clinical Epidemiology, Treviso, Italy, 3Pathology Unit, Treviso General Hospital, Department of Clinical Pathology, Treviso, Italy

P666

Changing disease patterns in Crohn's disease; experience from Malta

Authors:

J. Schembri*, N. Azzopardi, P. Ellul

Mater Dei Hospital, Department of Gastroenterology, Tal Qroqq, Malta

P667.

Low prevalence of Blastocystis sp. in active ulcerative colitis patients

Authors:

N. Rossen1, A. Bart2, N. Verhaar2, E. van Nood3, R. Kootte4, P. de Groot3, M. Nieuwdorp4, G. D'Haens1, C. Ponsioen1, T. van Gool2, 1Academic Medical Center, Gastroenterology & Hepatology, Amsterdam, Netherlands, 2Academic Medical Center Amsterdam, Department of Medical Microbiology, Parasitology Section, Amsterdam, Netherlands, 3Academic Medical Center Amsterdam, Department of Internal Medicine, Amsterdam, Netherlands, 4Academic Medical Center Amsterdam, Department of Vascular Medicine, Amsterdam, Netherlands

P667. Dissecting the role of unfolded protein response pathway in inflammatory bowel disease: in silico mRNA-miRNA co-expression analysis
Authors:

O. Palmieri1, F. Bossa1, M.T. Creanza2, T. Latiano1, G. Corritore1, D. Scimeca1, G. Biscaglia1, V.C. Liuzzi2, R. Anglani2, M. Carella3, V. Annese4, A. Andriulli1, A. Latiano1, 1IRCCS ‘Casa Sollievo della Sofferenza’ Hospital, Division of Gastroenterology, San Giovanni Rotondo, Italy, 2CNR, Istituto di Studi sui Sistemi Intelligenti per l'Automazione, Bari, Italy, 3IRCCS ‘Casa Sollievo della Sofferenza’ Hospital, Division of Medical Genetics, San Giovanni Rotondo, Italy, 4AOU Careggi, SOD2, Division of Gastroenterolgy, Firenze, Italy

P667

The effects of azathioprine/6-mercaptopurine and TNF-alpha antagonist on surgery in Korean patients with Crohn's disease from the CONNECT cohort

Authors:

H.M. Kim*1, H.-S. Kim1, J.H. Kim1, H.S. Kim1, K.J. Lee1, H.J. Park1, J.W. Kim1, J.S. Kim2, Y.S. Kim3, J.H. Cheon4, B.D. Ye5, Y.H. Kim6, D.S. Han7

1Yonsei University Wonju College of Medicine, Division of Gastroenterology and Hepatology, Wonju, South Korea, 2Seoul National Uinversity College of Medicine, Internal Medicine and Liver Research Institute, Seoul, Korea, Republic of, 3Inje University College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 4Yonsei University College of Medicine, Internal Medicine and Institute of Gastroenterology, Seoul, Korea, Republic of, 5University of Ulsan College of Medicine, Asan Medical Center, Gastroenterology and Inflammatory Bowel Disease Center, Seoul, Korea, Republic of, 6Sungkyunkwan University School of Medicine, Department of Internal Medicine, Seoul, Korea, Republic of, 7Hanyang University Guri Hospital, Department of Internal Medicine, Guri, Korea, Republic of