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P654

Relationship between use of complementary and alternative medicine (CAM) and health related quality of life (HRQoL) among patients with inflammatory bowel disease (IBD).

Authors:

R. Opheim*1, M. Lie Høivik1, T. Bernklev2, L.-P. Jelsness-Jørgensen3, 4, B. Moum1

1Oslo University Hospital, Department of Gastroenterology, Oslo, Norway, 2Telemark Hospital Trust, Research and Development Department, Skien, Norway, 3Østfold Hospital Trust, Department of Gastroenterology, Fredrikstad, Norway, 4Østfold University College, Faculty of Health and Social Studies, Fredrikstad, Norway

P655.

Gene expression alterations suggest that ulcerative colitis patients after restorative proctocolectomy have ileal disease

Authors:

H. Yanai1, S. Ben-Shachar2, L. Baram1, H. Elad1, A. Ofer1, G. Gitstein3, E. Brazowski3, H. Tulchinsky4, M. Pasmanik-Chor5, I. Dotan1, 1Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, IBD Center, Department of Gastroenterology and Liver Diseases, Tel Aviv, Israel, 2Tel Aviv Sourasky Medical Center affiliated to Sackler Faculty of Medicine, Tel Aviv university, Genetic institute, Tel Aviv, Israel, 3Tel Aviv Sourasky Medical Center, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Department of Pathology, Tel Aviv, Israel, 4Tel Aviv Sourasky Medical Center, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Proctology Unit, Department of Surgery, Tel Aviv, Israel, 5Tel Aviv University, Tel Aviv, Israel, Bioinformatics unit, G.S.W. Faculty of Life Sciences, Tel Aviv, Israel

P655. Diffuse jejunoileitis – a unique subtype of Crohn's disease?
Authors:

M. Majerovic1, M. Brinar1, M. Crncevic Urek1, S. Cukovic-Cavka1, B. Vucelic1, 1University Hospital Centre Zagreb, Division of Gastroenterology and Hepatology, Zagreb, Croatia

P655

Incidence and risk factors of Clostridium difficile infection in patients with inflammatory bowel disease

Authors:

O. Stoica1, A. Trifan*1, C. Cojocariu1, A.-M. Singeap1, I. Girleanu1, R. Maxim1, C. Stanciu2

1University of Medicine and Pharmacy "Gr. T Popa ", Iasi, Institute of Gastroenterology and Hepatology, Iasi, Romania, 2Institute of Gastroenterology and Hepatology, Bd. Independentei, no. 1, Gastroenterology and Hepatology, Iasi, Romania

P656.

Fcgamma Receptor Type IIIa polymorphisms and their correlation with clinical outcome in patients with inflammatory bowel disease during a long term follow up

Authors:

G. Bodini1, V. Savarino1,2, P. Dulbecco1,3, I. Baldissarro1,2, E. Savarino1,4,5, 1IRCCS San Martino Genova, Dipartimento di medicina interna, Genova, Italy, 2Universita di Genova, Dipartimento di medicina interna, Genova, Italy, 3Università di Genova, Dipartimento di Medicina Interna, Genova, Italy, 4University of Padua, Department of Surgery, Oncology and Gastroenterology, padova, Italy, 5Department of Surgery, Oncology and Gastroenterology, University of Padua, Gastroenterology Unit, Padua, Italy

P656. Decision-making on pregnancy in female inflammatory bowel disease patients
Authors:

J. Baars1, J. Hoekstra1, A. van Roon1, M. Kimmel1, A. van Tilburg1, R. West1, 1Sint Franciscus Gasthuis, Rotterdam, Netherlands

P656

Otorhinolaryngologic manifestations in Inflammatory Bowel Disease - Pilot study

Authors:

A. Oliveira*1, J.C. Ribeiro2, P. Freire1, M. Ferreira1, F. Portela1, C. Sofia1

1Coimbra Hospital and University Centre, Gastroenterology, Coimbra, Portugal, 2Coimbra Hospital and University Centre, Otorhinolaryngology, Coimbra, Portugal

P657.

Effects of isotretinoin treatment on epigenetic programming in T cells

Authors:

E. Becker, C. Stanzel, K. Atrott, G. Rogler, I. Frey-Wagner, University Hospital Zurich, Gastroenterology & Hepatology, Zurich, Switzerland

P657. Comparison of centers of reference for patients suffering from inflammatory bowel disease with points of call for patients with inflammatory rheumatic diseases across Austria using epidemiologic and real-life data
Authors:

A. Vavrovsky1, 1Academy for Value in Health GmbH, Vienna, Austria

P657

IBD in migrant South Asians: systematic review of epidemiology and disease phenotype

Authors:

R. Misra*1, O. Faiz2, N. Arebi1

1St Mark's Hospital, Inflammatory Bowel Disease Unit, London, United Kingdom, 2St Mark's Hospital, Colorectal Surgery & IBD Unit, London, United Kingdom

P658.

Effects of allopurinol on thiopurine metabolism and gene expression levels in HepG2 cells

Authors:

S. Haglund1, A. Zimdahl2, S. Vikingsson2, S. Almer3, J. Söderman1, 1Ryhov County Hospital, Division of Medical Diagnostics, Jönköping, Sweden, 2Linköping University, Department of Medical and Health Sciences, Linköping, Sweden, 3Karolinska University Hospital, GastroCentrum, Stockholm, Sweden

P658. Colorectal cancer in primary sclerosing cholangitis: the importance of surveillance
Authors:

K. Boonstra1, R. Weersma2, K.J. van Erpecum3, E. Rauws1, M. Spanier4, A. Poen5, K. van Nieuwkerk6, J. Drenth7, B. Witteman8, H. Tuynman9, A. Naber10, P. Kingma11, H. van Buuren12, B. van Hoek13, F. Vleggaar3, U. Beuers1, C. Ponsioen1, 1Academic Medical Center Amsterdam, Gastroenterology and Hepatology, Amsterdam, Netherlands, 2University Medical Center Groningen, Gastroenterology and Hepatology, Groningen, Netherlands, 3University Medical Center Utrecht, Gastroenterology and Hepatology, Utrecht, Netherlands, 4Rijnstate Hospital, Gastroenterology and Hepatology, Arnhem, Netherlands, 5Isala Clinics, Gastroenterology and Hepatology, Zwolle, Netherlands, 6VU Medical Center, Gastroenterology and Hepatology, Amsterdam, Netherlands, 7Radboud University Nijmegen Medical Center, Gastroenterology and Hepatology, Nijmegen, Netherlands, 8Gelderse Vallei Hospital, Gastroenterology and Hepatology, Ede, Netherlands, 9Medical Center Alkmaar, Gastroenterology and Hepatology, Alkmaar, Netherlands, 10Tergooiziekenhuizen, Gastroenterology and Hepatology, Hilversum, Netherlands, 11Tergooiziekenhuizen, Gastroenterology and Hepatology, Blaricum, Netherlands, 12Erasmus University Medical Center, Gastroenterology and Hepatology, Rotterdam, Netherlands, 13Leiden University Medical Center, Gastroenterology and Hepatology, Leiden, Netherlands

P658

Inflammatory Bowel Disease and the Risk of Other Autoimmune Diseases

Authors:

J.C. Wilson*1, R. Furlano2, S. Jick3, C. Meier1, 4

1University of Basel, Department of Pharmaceutical Sciences, Basel, Switzerland, 2University Childrens Hospital Basel, University Childrens Hospital Basel,, Basel, Switzerland, 3Boston University School of Public Health, Boston Collaborative Drug Surveillance Program, Lexington, United States, 4University Hospital Basel, Basel Pharmacoepidemiology Unit, Basel, Switzerland

P659.

Crohn's disease in an Irish population – a pilot genotype–phenotype analysis

Authors:

B. Hall1,2, G. Holleran1,2, S. O'Sullivan3, S. Smith2, C. Medina3, D. McNamara1,2, 1Trinity College Dublin, Department of Clinical Medicine, Dublin, Ireland, 2Adelaide and Meath Hospital, Department of Gastroenterology, Dublin, Ireland, 3Trinity College Dublin, Dublin, Ireland, School of Pharmacy and Pharmaceutical Sciences, Dublin, Ireland

P659. Clinical features of Crohn's disease at diagnosis: a Korean multicenter nationwide cohort study
Authors:

B.D. Ye1, J.W. Kim2, D.S. Han3, E.J. Youn1, J.H. Lee4, H.-S. Kim5, S.J. Park6, H.-S. Kim7, Y.S. Kim8, Y.-H. Kim9, C.H. Choi10, K.-M. Lee11, C.K. Lee12, S.-K. Yang1, H.J. Kim12, W.H. Kim6, 1Asan Medical Center, Gastroenterology, Inflammatory Bowel Disease Center, Seoul, South Korea, 2Seoul National University Borame Hospital, Internal Medicine, Seoul, South Korea, 3Hanyang University Guri Hospital, Internal Medicine, Guri, South Korea, 4Seoul Song Do Colorectal Hospital, Digestive Endoscopic Center, Seoul, South Korea, 5Chonnam National University Medical School, Internal Medicine, Gwangju, South Korea, 6Yonsei University College of Medicine, Internal Medicine, Institute of Gastroenterology, Seoul, South Korea, 7Yonsei University Wonju College of Medicine, Internal Medicine, Wonju, South Korea, 8Seoul Paik Hospital, Inje University, College of Medicine, Internal Medicine, Seoul, South Korea, 9Samsung Medical Center, Sungkyunkwan University School of Medicine, Medicine, Seoul, South Korea, 10Chung-Ang University College of Medicine, Internal Medicine, Seoul, South Korea, 11St. Vincent's Hospital, College of Medicine, The Catholic University of Korea, Internal Medicine, Suwon, South Korea, 12Kyung Hee University Medical Center, Kyung Hee University College of Medicine, Internal Medicine, Seoul, South Korea

P659

Knowledge and attitude of patient toward Ulcerative Colitis and disease activity in Europe: The UC CARES (Ulcerative Colitis Condition, Attitude, Resources and Educational Study)

Authors:

G. Van Assche1, L. Peyrin-Biroulet2, S. Kachroo*3, Q. Ding4, T. Fan3, P. Singhal3, M. Lynam5, S. Rojas-Farreras5, L. Nuria5

1University Hospital Leuven, Gastroenterology, Leuven, Belgium, 2Nancy University Hospital, Université de Lorraine, Gastroenterology and Hepatology, Vandoeuvre-les-Nancy, France, 3Merck & Co., Inc, Global Health Outcomes, Whitehouse Station, United States, 4Temple University, Department of Pharmacy Practice, Philadelphia, United States, 5IMS Health, Health Economics and Outcomes Research, Barcelona, Spain

P660.

Crohn's disease course is not different in familial than in sporadic cases: A case–control population-based study

Authors:

R. Gérard1, H. Sarter2, M. Fumery3, L. Dauchet4, E. Joyez4, F. Vasseur4, J.-F. Colombel5, D. Turck6, L. Peyrin-Biroulet7, G. Savoye8, C. Gower-Rousseau4,9, 1University and Hospital, Gastroenterology, Lille, France, 2University and Hospital, Epimad Registry Biostatistics EA 2694, Lille, France, 3University and Hospital, Gastroenterology, Amiens, France, 4University and Hospital, Epidemiology, Lille, France, 5Hemsley Inflammatory Bowel Disease Center, Icahn Medical School of Medicine at Mount Sinai, New-York, United States, 6University and Hospital, Paediatric, Lille, France, 7University and Hospital, Gastroenterology, Nancy, France, 8University and Hospital, Gastroenterology, Rouen, France, 9Health, Epidemiology, Lille, France

P660. Clinical characteristics of new onset IBD: report from the web based Registry of Italian Group for IBD
Authors:

A. Redaelli1, M. Milla2, R. D'Incà3, F. Sasso4, A. Orlando5, D. Valpiani6, A. Cirillo4, R. Pica7, A. Geccherle8, V. Annese2, on behalf of IG-IBD, 1Gastronterology, Monza, Italy, 2Gastroenterology, Florence, Italy, 3Gastroenterology, Padua, Italy, 4Gastroenterology, Naples, Italy, 5Gastroenterology, Palermo, Italy, 6Gastroenterology, Forlì, Italy, 7Gastroenterology, Rome, Italy, 8Gastroenterology, Negrer-Verona, Italy

P660

Estimation of cardiovascular risk according to asymptomatic organ damage in subjects with inflammatory bowel disease

Authors:

G. Inserra*, L. Zanoli, A. Ricciardolo, V. Ficara, L. Samperi, G. Riguccio

University of Catania, Department of clinical and experimental medicine, Catania, Italy

P661.

Case–control study and meta-analysis of glutathione S-transferase polymorphisms in patients with inflammatory bowel disease

Authors:

M. Broekman, C. Bos, R.H. te Morsche, F. Hoentjen, H.M. Roelofs, W.H. Peters, G.J. Wanten, D.J. de Jong, Radboud UMC, Gastroenterology & Hepatology, Nijmegen, Netherlands