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Correlation between adalimumab serum levels and remission after the induction phase in Crohn's Disease patients

M. Chaparro*¹, I. Guerra², M. Iborra³, J.L. Cabriada⁴, L. Bujanda⁵, C. Taxonera⁶, V. García-Sánchez⁷, I. Marín-Jiménez⁸, M. Barreiro de-Acosta⁹, I. Vera¹⁰, M.D. Martín-Arranz¹¹, B. Hernández-Breijo¹², F. Mesonero¹³, L. Sempere¹⁴, Y. Ber¹⁵, M.D. Hinojosa¹⁶, M. Ramas¹, F. Bermejo², B. Beltrán³, I. Rodriguez-Lago⁴, J.M. Banales¹⁷, J.L. Mendoza⁶, P. Aguilar-Melero⁷, L. Menchén⁸, R. Ferreiro⁹, I. Blazquez¹⁰, B. Benítez García¹¹, L. Guijarro¹², P.M. Linares¹, J.P. Gisbert¹

¹Hospital Universitario de La Princesa, IIS-IP and CIBERehd, Gastroenterology Unit, Madrid, Spain, ²Hospital Universitario de Fuenlabrada, Gastroenterology Unit, Madrid, Spain, ³Hospital Universitario La Fe and CIBERehd, Gastroenterology Unit, Valencia, Spain, ⁴Hospital Galdakao, Gastroenterology Unit, Vizcaya, Spain, ⁵Hospital de Donostia, Instituto Biodonostia, UPV/EHU and CIBEREHD, Gastroenterology Unit, Guipuzcoa, Spain, ⁶Hospital Clínico Universitario San Carlos and IdISSC, Gastroenterology Unit, Madrid, Spain, ⁷Hospital Universitario Reina Sofía, Gastroenterology Unit, Córdoba, Spain, ⁸Hospital General Universitario Gregorio Marañón, Gastroenterology Unit, Madrid, Spain, ⁹Complejo Hospitalario Universitario de Santiago, Gastroenterology Unit, Santiago de Compostela, Spain, ¹⁰Hospital Universitario Puerta de Hierro , Gastroenterology Unit, Madrid, Spain, ¹¹Hospital Universitario La Paz , Gastroenterology Unit, Madrid, Spain, ¹²Universidad de Alcalá and CIBERehd, Systems Biology, Alcalá de Henares, Spain, ¹³Hospital Universitario Ramón y Cajal, Gastroenterology Unit, Madrid, Spain, ¹⁴Hospital General Universitario de Alicante, Gastroenterology Unit, Alicante, Spain, ¹⁵Hospital Clínico Universitario Lozano Blesa and CIBERehd, Gastroenterology Unit, Zaragoza, Spain, ¹⁶Hospital de Manises, Gastroenterology Unit, Valencia, Spain, ¹⁷Hospital de Donostia, Instituto Biodonostia, UPV/EHU and CIBEREHD, Gastroenterology Unit, San Sebastián, Spain

Epidemiology and hospital resources use in the treatment of ulcerative colitis at gastroenterology units in Spain (EPICURE Study)

I. Marin-Jimenez¹, C. Saro², V. Díaz³, M. Barreiro-de Acosta⁴, M. Gómez-García⁵, N. Borruel⁶, A. Gutierrez⁷, ¹Hospital General Universitario Gregorio Marañón, Gastroenterology section – Digestive System Medicine Department, Madrid, Spain, ²Hospital de Cabueñes, Digestive Department, Gijon, Spain, ³AbbVie Farmacéutica S.L.U., Inmunology, Madrid, Spain, ⁴Hospital Clínico Universitario, Gastroenterology – Inflammatory Bowel Disease Unit, Santiago de Compostela, Spain, ⁵Hospital Universitario Virgen de las Nieves, Digestive Department, Granada, Spain, ⁶Hospital Vall d'Hebrón, Digestive Department, Barcelona, Spain, ⁷Hospital General Universitario, Digestive Medicine Department, Alicante, Spain

P628. Prevalence of extraintestinal manifestations (EIMs) in inflammatory bowel disease (IBD) patients of a southern Italian single centre

G. Inserra¹, M. Mendolaro¹, M.C. Conti Bellocchi¹, L. Samperi¹, ¹A.O.U. Policlinico-Vittorio Emanuele, U.O. Medicina interna, Catania, Italy

Anti-TNF treatment and renal cell carcinoma in patients with inflammatory bowel disease, rheumatoid arthritis and spondyloarthropathy: trigger or cure?

L. Wauters*¹, S. Joniau², P. Verschueren³, G. Van Assche¹, S. Vermeire¹, M. Ferrante¹

¹University Hospital Leuven, Department of Gastroenterology, Leuven, Belgium, ²University Hospital Leuven, Department of Urology, Leuven, Belgium, ³University Hospital Leuven, Department of Rheumatology, Leuven, Belgium

Epidemiological features and disease related concerns of a large cohort of Italian patients with active Crohn's disease

A. Armuzzi¹, G. Riegler², M. Vecchi³, M. Baldoni⁴, F. Costa⁵, M. Fortuna⁶, F. Furfaro⁷, G. Iaquinto⁸, P. Paese⁹, C. Papi¹⁰, F. Rizzello¹¹, V. Tornatore¹², F. Bossa¹³, ¹Catholic University, IBD Unit, Complesso Integrato Columbus, Rome, Italy, ²Second University of Naples, Gastroenterology, Naples, Italy, ³IRCCS Policlinico San Donato, Gastroenterology, Milan, Italy, ⁴University of Perugia, Gastroenterology, Perugia, Italy, ⁵Azienda Ospedaliero-Universitaria Pisana, Gastroenterology, Pisa, Italy, ⁶Hospital Sacro Cuore Don Calabria, Gastroenterology, Negrar-Verona, Italy, ⁷University Hospital L. Sacco, Gastroenterology, Milan, Italy, ⁸Azienda Ospedaliera San Giuseppe Moscati, Gastroenterology, Avellino, Italy, ⁹Azienda Ospedaliera di Cosenza, Gastroenterology, Cosenza, Italy, ¹⁰Azienda Ospedaliera San Filippo Neri, Gastroenterology, Rome, Italy, ¹¹University of Bologna, Dipartimento di Scienze Mediche e Chirurgiche (DIMEC), Bologna, Italy, ¹²AbbVie srl, Medica Department, Campoverde di Aprilia, Italy, ¹³Ospedale Casa Sollievo della Sofferenza, Gastroenterology, San Giovanni Rotondo, Italy

P629. Mortality and causes of death in Crohn's disease: Results from a Norwegian population-based twenty-year follow-up study (IBSEN20)

Ø. Hovde¹, I. Kempski-Monstad², I.C. Solberg², M. Cvancarova³, B. Moum⁴, ¹Innlandet Hospital Trust/University of Oslo, Department of Gastroenterology, Gjøvik/Oslo, Norway, ²Oslo University Hospital, Department of Gastroenterology, Oslo, Norway, ³Oslo University Hospital, Section for Biostatistics, Oslo, Norway, ⁴Oslo University Hospital/University of Oslo, Department of Gastroenterology, Oslo, Norway

Adherence - does patient involvement and satisfaction matter?

P. Bager*, M. Julsgaard, T. Vestergaard, L. Ambrosius Christensen, J. Frederik Dahlerup

Aarhus University Hospital, Department of Hepatology and Gastroenterology, Aarhus , Denmark

Epidemiological and phenotypic characteristics of IBD patients in Romania – results of a nationwide hospital-based registry

C. Gheorghe¹, A. Dimitriu¹, R. Iacob¹, M. Cojocaru¹, C. Lupei¹, R. Vadan¹, D. Dobru², A. Trifan³, M. Tantau⁴, A. Goldis⁵, G. Constantinescu⁶, S. Gologan⁷, B. Mateescu⁸, D. Gheonea⁹, L. Gheorghe¹, M. Diculescu¹, on behalf of the IBDPROSPECT Study Group, ¹Fundeni Clinical Institute, Digestive Diseases and Liver Transplantation Center, Bucharest, Romania, ²Municipal Hospital Targu Mures, Gastroenterology, Targu Mures, Romania, ³Gastroenterology and Hepatology Institute Iasi, Gastroenterology, Iasi, Romania, ⁴3rd Medical Clinic Cluj-Napoca, Gastroenterology, Cluj-Napoca, Romania, ⁵District Hospital Timisoara, Gastroenterology, Timisoara, Romania, ⁶Floreasca Emergency Hospital, Gastroenterology, Bucharest, Romania, ⁷Elias Universitary Hospital, Gastroenterology, Bucharest, Romania, ⁸Colentina Clinical Hospital, Gastroenterology, Bucharest, Romania, ⁹University of Medicine and Pharmacy Craiova, Romania, Immunology, Craiova, Romania

P630. Inflammatory bowel disease in celiac patients

A. Hernandez Camba¹, I. Alonso¹, N. Hernandez Alvarez-Buylla¹, M. Carrillo¹, L. Ramos¹, E. Quintero¹, ¹Hospital Universitario de Canaris, Gastroenterology, La Laguna, Spain

Efficacy of TNF -alpha therapy in Crohn's disease: A 5-year retrospective cohort study in an intermediate sized hospital

C. Quaade Michelsen¹, S. Wildt*², L.K. Munck²

¹Koege Hospital, University Hospital of Copenhagen, Department of Medicine, section of gastroenterology, Koege, Denmark, ²Koege Hospital, University Hospital of Copenhagen, Department of medicine, section of gastroenterology, Koege, Denmark

ERAP-1 gene polymorphisms in Turkish patients with inflammatory bowel diseases and anyklosing spondylitis

O. Kucuksahin¹, N. Turkcapar¹, A. Ates¹, M. Törüner², T. Duman³, H. Cetinkaya², M. Turgay¹, G. Kinikli¹, N. Duzgun¹, ¹Ankara University School of Medicine, Department of Rheumatology, Ankara, Turkey, ²Ankara University School of Medicine, Department of Gastroenterology, Ankara, Turkey, ³Ankara University School of Medicine, Department of Immunology and Allergy, Ankara, Turkey

P631. Natural history of elderly onset inflammatory bowel disease – Sydney IBD Cohort (1942–2012)

V. Kariyawasam¹, P. Lunney², T. Huang², K. Middleton², R. Wang², C. Selinger², P. Katelaris², J. Andrews³, R. Leong², ¹Guy's and St Thomas' NHS Foundation Trust, Gastroenterology, Londond, United Kingdom, ²Concord Repatriation General Hospital, Gastroenterology, Concord, Australia, ³Royal Adelaide Hospital, Dept of Gastroenterology & Hepatology, Adelaide, Australia

Mesalamine versus azathioprine for maintenance treatment after steroid-induced remission in pediatric ulcerative colitis

D. Sánchez Hernández*, C. Ruiz Hernández, G. Pujol Muncunill, V. Varea Calderón, J. Martín de Carpi

Hospital Sant Joan de Déu, Pediatric IBD Unit, Barcelona, Spain

Dietary practices in patients with inflammatory bowel disease – food for thought

H. Burns¹, D. Aggarwal¹, J.T. McLaughlin², J.K. Limdi¹, ¹The Pennine Acute Hospitals NHS Trust, Department of Gastroenterology, Manchester, United Kingdom, ²University of Manchester, Institute of Inflammation and Repair, Manchester, United Kingdom

P632. Long-term outcome of paediatric-onset ulcerative colitis: early years are shaping the future

C. Gower-Rousseau¹, J. Salleron², D. Turck³, M. Fumery⁴, A. Peneau⁵, C. Spyckerelle⁶, J.-E. Laberenne⁷, F. Vasseur¹, L. Peyrin-Biroulet⁸, J.-F. Colombel⁹, G. Savoye¹⁰, ¹University Hospital, Epidemiology EA 2694, Lille, France, ²University Hospital EA 2694, Biostatistics, Lille, France, ³University Hospital, Pediatric Unit, Lille, France, ⁴Amiens University and Hospital, Gastroenterology, Amiens, France, ⁵Lille University Hospital, Gastroenterology, Lille, France, ⁶St Vincent Hospital, Paediatric Unit, Lille, France, ⁷Hospital, Gastroenterology, Seclin, France, ⁸University Hospital, Gastroenterology, Nancy, France, ⁹University Hospital, Gastroenterology, Lille, France, ¹⁰University Hospital, Gastroenterology, Rouen, France

Thiopurine metabolite (TM) monitoring in Adolescent IBD (aIBD): Non- and poor adherence is common adolescent practice

F. Kiparissi*^{1, 2}, L. Whitley², C. Murray³, A. Dawney², S. McCartney²

¹Great Ormond Street Hospital, Paediatric Gastroenterology, London, United Kingdom, ²University College London Hospitals NHS Foundation Trust, Department of Gastroenterology, London, United Kingdom, ³Royal Free London NHS Foundation Trust, Department of Gastroenterology, London, United Kingdom

Decision-making, counselling and course of pregnancy in female inflammatory bowel disease patients

J. Hoekstra¹, J. Baars¹, A. van Roon¹, M. Kimmel¹, M. Zwijnenburg², F. Bekkering², A. van Tilburg¹, R. West¹, ¹Sint Franciscus Gasthuis, Gastroenterology and Hepatology, Rotterdam, Netherlands, ²IJsselland Hospital, Gastroenterology and Hepatology, Capelle aan den IJssel, Netherlands

P633. Inflammatory bowel disease and risk of pre-eclampsia and preterm delivery: a national birth cohort study

M. Harpsøe¹, H. Boyd¹, S. Usmann¹, J. Wohlfahrt¹, T. Jess¹, ¹Statens Serum Institut, Department of Epidemiology Research, Denmark

Does computerised cognitive behavioural therapy help people with Inflammatory Bowel Disease? A randomized controlled trial

A. McCombie*¹, R. Gearry², R. Mulder¹, J. Andrews³, A. Mikocka-Walus⁴

¹University of Otago, Medicine, Christchurch, New Zealand, ²University of Otago, Christchurch Hospital, Medicine and Gastroenterology, Christchurch, New Zealand, ³Royal Adelaide Hospital, Gastroenterology and Hepatology, Adelaide, Australia, ⁴University of York, Health Sciences, York, United Kingdom

Comparison of mortality following hospitalisation for ulcerative colitis in Scotland between 1998–2000 and 2007–2009

N. Ventham¹, N. Kennedy¹, A. Duffy², D. Clark², A. Crowe³, A. Knight³, J. Nicholls⁴, J. Satsangi¹, ¹NHS Lothian, Gastroenterology, Edinburgh, United Kingdom, ²NHS National Services, Information Services Division, Edinburgh, United Kingdom, ³Corvus Communications Ltd, Buxted, United Kingdom, ⁴Imperial College, St Mary's Campus, London, United Kingdom