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Health care consumption and treatment of ulcerative colitis in Stockholm County

M. Lördal^1,2, B. Wettermark³, T. Cars⁴, ¹Karolinska Institutet, Department of Gastroenterology and Hepatology, Stockholm, Sweden, ²Karolinska Institutet, Department of Medicine, Stockholm, Sweden, ³Department of Medicine, Centre for Pharmacoepidemiology, Karolinska Institutet, Public Healthcare Services committee, Stockholm County Council, Stockholm, Sweden, ⁴Public Healthcare Services committee, Stockholm County Council, Public Healthcare Services committee, Stockholm County Council, Stockholm, Sweden

P621. The natural history of inflammatory bowel disease (IBD) in an Australian based community cohort: investigating predictors of severe disease and risk of complications

O. Niewiadomski¹, J. Ding², R. Knight², D. Paul², C. Hair², P. Emily², S. Alexander², D. Dowling¹, B. Popp², J. Wilson¹, C. Studd¹, P. Desmond¹, J. McNeil³, W. Connell¹, S. Bell¹, ¹St Vincent's Hospital, Gastroenterology Dept, Fitzroy, Australia, ²Geelong Hospital, Australia, ³Monash University, Australia

Comparison between total abdominal colectomy and segmental colectomy in Crohn's colitis patients: Recurrence and re-resection rates. A retrospective cohort study

H. Tulchinsky*¹, M. Bendersky², H. Yanai³, J. Klausner², I. Dotan³

¹Tel Aviv Medical Center, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Colorectal Unit, Department of Surgery, Tel Aviv, Israel, ²Tel Aviv Medical Center, affiliated to Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Department of Surgery, Tel Aviv, Israel, ³Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, IBD Center, Department of Gastroenterology and Liver Diseases, Tel Aviv, Israel

Health care consumption and treatment of Crohn's disease in Stockholm County

M. Lördal^1,2, T. Cars³, B. Wettermark⁴, ¹Karolinska Institutet, Department of Gastroenterology and Hepatology, Stockholm, Sweden, ²Karolinska Institutet, Department of Medicine, Stockholm, Sweden, ³Public Healthcare Services committee, Stockholm County Council, Public Healthcare Services committee, Stockholm County Council, Stockholm, Sweden, ⁴Department of Medicine, Centre for Pharmacoepidemiology, Karolinska Institutet, Public Healthcare Services committee, Stockholm County Council, Stockholm, Sweden

P622. Smoking, breastfeeding, physical inactivity, contact with animals, and size of the family influence the risk of inflammatory bowel diseases in a Slovak case-control study

T. Hlavaty¹, J. Toth¹, T. Koller¹, A. Krajcovicova¹, S. Oravcova¹, Z. Zelinkova¹, M. Huorka¹, ¹University hospital Bratislava, Bratislava, Slovakia

Infusion-related reactions with vedolizumab treatment in patients with UC or CD during the GEMINI 1 and GEMINI 2 clinical trials

B.E. Sands*¹, R. Cohen², K. Isaacs³, R.N. Fedorak⁴, B. Abhyankar⁵, S. Sankoh⁶, M. Smyth⁷

¹Icahn School of Medicine at Mount Sinai Hospital, Gastroenterology, New York, United States, ²The University of Chicago Medicine, Medicine, Chicago, IL, United States, ³UNC School of Medicine, Medicine, North Carolina, United States, ⁴University of Alberta, Medicine, Edmonton, Alberta, Canada, ⁵Takeda Global Research and Development Centre (Europe) Ltd., Clinical Science, London, United Kingdom, ⁶Takeda Pharmaceuticals International Co., Statistics, Cambridge, Massachusetts, United States, ⁷Takeda Global Research and Development Centre (Europe) Ltd., Medical, London, United Kingdom

Forty-year analysis of colonoscopic surveillance program for ulcerative colitis

C.H. Choi¹, M. Rutter², M. Kang³, J. Warusavitarne¹, S. Thomas-Gibson¹, M. Moorghen¹, B. Saunders¹, T. Graham⁴, A. Hart¹, ¹St Mark's Hospital, Department of IBD, Colorectal Surgery and Wolfson Unit of Endoscopy, London, United Kingdom, ²University Hospital of North Tees, Department of Gastroenterology, Stockton-on-Tees, Teesside, United Kingdom, ³Imperial College London, School of Medicine, London, United Kingdom, ⁴Queen Mary University of London, Centre for Tumour Biology, Barts Cancer Institute, London, United Kingdom

P623. Similar clinical characteristics of familial and sporadic inflammatory bowel disease

S.H. Chung¹, S.J. Park¹, H.S. Lee², J.H. Cheon¹, S.P. Hong¹, T.I. Kim¹, W.H. Kim¹, ¹Yonsei University College of Medicine and institute of Gastroenerology, South Korea, ²Yonsei University College of Medicine, Department of Biostatistics, South Korea

Steroids no more! Exclusive Enteral Nutrition therapy in pediatric patients with Crohn's Disease Results in long-term avoidance of corticosteroid therapy

A. Otley*¹, A. Grant², N. Giffin³, G. Mahdi¹, M. Rashid¹, J. Van Limbergen¹

¹IWK Health Centre - Dalhousie University, Pediatric Gastroenterology & Nutrition, Halifax, Canada, ²IWK Health Centre, Gastroenterology, Halifax, Canada, ³Dalhousie University, Undergraduate Medical Education, Halifax, Canada

Food and microbial IgG and IgA levels in the serum and feces of patients with inflammatory bowel disease and controls

L. Frehn, A. Jansen, I. Temizel, S. Tischendorf, E. Bennek, A.D. Mandic, J. Verdier, K. Streetz, C. Trautwein, G. Sellge, University Hospital, RWTH Aachen, Department of Internal Medicine III, Aachen, Germany

P624. Risk of colorectal cancer in CD patients with colonic involvement and stenosing disease. Results from a population-based study

P.A. Golovics¹, L. Lakatos², B.D. Lovasz¹, G. David², T. Pandur², Z. Erdelyi², G. Mester³, M. Balogh³, I. Szita², C. Molnar⁴, E. Komaromi⁵, Z. Vegh¹, M. Mandel¹, L.S. Kiss¹, P. Lakatos¹, ¹Semmelweis University, 1st Department of Medicine, Budapest, Hungary, ²Csolnoky F. Province Hospital, 1st Department of Medicine, Veszprem, Hungary, ³Grof Eszterhazy Hospital, Papa, Hungary, ⁴Magyar Imre Hospital, Ajka, Hungary, ⁵Municipal Hospital, Varpalota, Hungary

Impaired intestinal barrier function promotes procoagulatory state in Inflammatory Bowel Diseases

L. Pastorelli*^{1, 2}, E. Dozio², L.F. Pisani¹, M. Boscolo-Anzoletti³, E. Vianello², N. Munizio¹, L. Spina¹, G.E. Tontini¹, F. Peyvandi^{3, 4}, M.M. Corsi Romanelli^{2, 5}, M. Vecchi^{1, 2}

¹IRCCS Policlinico San Donato, Gastroenterology and Gastrointestinal Endoscopy Unit, San Donato Milanese, Italy, ²University of Milan, Department of Biomedical Sciences for Health, Milan, Italy, ³IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Centre, Milan, Italy, ⁴University of Milan, Department of Medical and Surgical Pathophisiology and Transplantations, Milan, Italy, ⁵IRCCS Policlinico San Donato, Operative Unit of Laboratory Medicine, San Donato Milanese, Italy

Features of familial Crohn's disease: A comparative retrospective study

M. Serghini¹, A. Labidi¹, L. Zouiten¹, N. Ben Mustapha¹, M. Fekih¹, J. Boubaker¹, A. Filali¹, ¹La Rabta Hospital, Gastroenterology A, Tunis, Tunisia

P625. Risk of cancer in patients with inflammatory bowel disease: a population-based study

A. Algaba¹, I. Guerra¹, A. Castaño², G. de la Poza¹, V.M. Castellano², M. López², F. Bermejo¹, ¹Hospital Universitario de Fuenlabrada, Gastroenterology, Fuenlabrada, Spain, ²Hospital Universitario de Fuenlabrada, Pathology, Fuenlabrada, Spain

Use of infliximab (Remicade®) for IBD within a patient support program: Positive perception of i.v. infusions from patient's perspective

J. Jones¹, M. Borgaonkar², J. Siffledeen³, D. Dajnowiec*⁴, P. Dyrda⁵

¹Dalhousie University, QE II Health Sciences Center, Gastroenterology, Halifax, Canada, ²Memorial University, Gastroenterology, St. John's, Canada, ³University of Alberta, Gastroenterology, Edmonton, Canada, ⁴Janssen Canada, Medical Affairs, Toronto, Canada, ⁵Janssen Canada, Market Access, Toronto, Canada

Extraintestinal manifestations in Romanian IBD patients – evaluation of a cohort of over 1000 patients

R. Iacob¹, L. Guinea¹, R. Vadan¹, M. Greere¹, C. Preda¹, D. Dobru², C. Cijevschi-Prelipcean³, A. Tantau⁴, A. Goldis⁵, M. Ilie⁶, M. Andrei⁷, L. Negreanu⁸, C. Gheorghe¹, M. Diculescu¹, L. Gheorghe¹, on behalf of the IBDPROSPECT Study Group, ¹Fundeni Clinical Institute, Digestive Diseases and Liver Transplantation Center, Bucharest, Romania, ²Municipal Hospital Targu Mures, Gastroenterology, Targu Mures, Romania, ³Gastroenterology and Hepatology Institute Iasi, Gastroenterology, Iasi, Romania, ⁴CFR Hospital Cluj-Napoca, Gastroenterology, Cluj-Napoca, Romania, ⁵District Hospital Timisoara, Gastroenterology, Timisoara, Romania, ⁶Floreasca Emergency Hospital, Gastroenterology, Bucharest, Romania, ⁷Elias Universitary Hospital, Gastroenterology, Bucharest, Romania, ⁸Universitary Hospital Bucharest, Gastroenterology, Bucharest, Romania

P626. Prevalence of different immune mediated inflammatory diseases in patients with inflammatory bowel disease. AQUILES study

I. Marín-Jiménez¹, F. Gómez², J.P. Gisbert³, J.L. Pérez-Calle⁴, M. Luján⁵, J. Gordillo⁶, I. Moral⁷, M. Andreu⁸, L. Cea Calvo⁹, R. García de Vicuña¹⁰, F. Vanaclocha¹¹, C. Romero⁹, ¹Gregorio Marañón Hospital, Spain, ²Reina Sofía Hospital, Spain, ³La Princesa Hospital & CIBEREHD, Spain, ⁴Alcorcón Foundation Hospital, Spain, ⁵Valencia General Hospital Consortium, Spain, ⁶Santa Creu i Sant Pau Hospital, Spain, ⁷Príncipe de Asturias Hospital, Spain, ⁸del Mar Hospital, Spain, ⁹Merck Sharp & Dohme de España, Spain, ¹⁰La Princesa Hospital IISP, Spain, ¹¹12 de Octubre Hospital, Spain

Histological improvement after induction therapy with infliximab provide prolonged clinical remission during maintenance therapy in children with Crohn disease.

M. Dadalski*¹, E. Szymanska², W. Grajkowska³, J. Kierkus⁴

¹The Children's Memorial Health Institute, Gastroenterology, Hepatology, Feeding Disorders and Paediatrics, Warsaw, Poland, ²The Children's Memorial Health Institute, Paediatrics, Warsaw, Poland, ³Children's Memorial Health Institute, Pathology, Warsaw, Poland, ⁴Children's Memorial Health Institute, Gastroenterology, Hepatology, Feeding Disorders and Paediatrics, Warsaw, Poland

Exaggeration of physical symptoms in inflammatory bowel disease: Relation to depression, anxiety and quality of life

B. Kara¹, Y. Ozenli², S. Yalaki³, ¹Adana Bumune Research and Education Hospital, Gastroenterology, Adana, Turkey, ²Adana Numune Research and Education Hospital, Psychiatry, Adana, Turkey, ³Adana Numune Research and Education Hospital, Gastroenterology, Adana, Turkey

P627. Peripheral mesenteric vein thromboses are frequently found in IBD patients and are associated with intestinal surgery in Crohn's disease

A. Schoepfer¹, N. Vietti Violi², N. Fournier³, A. Denys², ¹University Hospital Lausanne / CHUV, Gastroenterology and Hepatology, Lausanne, Switzerland, ²University Hospital Lausanne / CHUV, Radiology, Lausanne, Switzerland, ³University of Lausanne, Institute of Social and Preventive Medicine, Lausanne, Switzerland