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P594. Anti-TNF alpha therapy and mucosal healing: the key to change the story of pediatric Crohn's disease?
Authors:

F. Nuti1, C. Alessandri1, A. Dilillo1, F. Civitelli1, M. Aloi1, G. Di Nardo1, S. Cucchiara1, F. Viola1, 1Sapienza University, Pediatrics, Gastroenterology and Liver Unit, Rome, Italy

P594

Systematic information to healthcare professionals about ECCO's vaccination guidelines improves adherence in patients with inflammatory bowel disease receiving anti-TNF α therapy

Authors:

K. Risager Christensen, C. Steenholdt, S. Schnoor Buhl, M.A. Ainsworth, O. Østergaard Thomsen*, J. Brynskov

Herlev University Hospital, Department of Gastroenterology, Copenhagen, Denmark

P595.

Smoking in patients with IBD: increasing smoking rates and alarmingly low use of supportive measures to achieve smoking cessation – Data from the Swiss IBD cohort study

Authors:

L. Biedermann1, N. Fournier2, B. Misselwitz1, P. Frei1,3, J. Zeitz1, C.N. Manser1, V. Pittet2, M. Fried1, S.R. Vavricka1,4, G. Rogler1, 1University Hospital Zurich, Gastroenterology & Hepatology, Zurich, Switzerland, 2University of Lausanne, IUMSP, Lausanne, Switzerland, 3Seespital Horgen, Gastroenterology & Hepatology, Horgen, Switzerland, 4Hospital Triemli, Gastroenterology & Hepatology, Zurich, Switzerland

P595. Anti-TNF alfa therapy in patients with inflammatory bowel disease and coronary syndrome: efficacy and safety
Authors:

A. Indriolo1, M. Senni2, P. Ravelli1, 1Ospedali Riuniti di Bergamo, Gastroenterology and Digestive Endoscopy Unit II, Bergamo, Italy, 2Ospedali Riuniti di Bergamo, Cardiovascular Unit, Bergamo, Italy

P595

Azathioprine is effective and safe in inducing and maintaining deep remission in Crohn's disease

Authors:

J. Tang*, X. Gao, M. Zhi, P. Hu

The Sixth Affiliated Hospital of Sun Yat-sen University, Department of Gastroenterology, Guangzhou, China

P596.

Risk factors for depression and anxiety in Crohn's disease

Authors:

F. Furfaro1, D. Gridavilla1, C. Bezzio1, L. Orlandini1, A. Dell'Era2, M. Monteleone1, S. Ardizzone1, G. Maconi1, 1Luigi Sacco University Hospital, Gastroenterology and IBD Unit, Milan, Italy, 2Luigi Sacco University Hospital, Gastroenterology Department, Milano, Italy

P596. Altered calcium homeostasis and the disease activity in patients with Crohn's disease and ulcerative colitis
Authors:

J. Beilfuss1, M. Heide2, J. Florholmen1, E. Kamycheva1, 1University Hospital of North Norway, Department of Gastroenterology, Tromsoe, Norway, 2University of Tromsoe, Faculty of Medicine, Tromsoe, Norway

P596

Efficacy and Nephrotoxicity of Long-term Maintenance Therapy with Tacrolimus in Patients with Ulcerative Colitis

Authors:

S. Tsuda*1, R. Kunisaki1, T. Ogashiwa1, H. Yasuhara1, R. Koh1, S. Tsunoda1, S. Yamamoto1, N. Kawashima1, R. Kubota1, K. Yazawa1, K. Goto1, H. Kimura1, S. Maeda2

1Yokohama City University Medical centre, Inflammatory Bowel Disease Centre, Yokohama, Japan, 2Yokohama City University Graduate School of Medicine, Gastroenterology, Yokohama, Japan

P597.

Reduced recurrence rates in Crohn's disease in the era of biological therapy: A 7-year population-based follow-up study of inflammatory bowel disease

Authors:

M. Kajbæk Vester-Andersen1, I. Vind1, M. Prosberg1, T. Jess2, M. Anderson3, B. Bengtsson4, T. Blixt5, F. Bendtsen1, 1Copenhagen University Hospital, Hvidovre, Department of Gastroenterology, Hvidovre, Denmark, 2National Health Surveillance and Research, Department of Epidemiological Research, Copenhagen, Denmark, 3Department of Epidemiological Research, National Health Surveillance and Research, Copenhagen, Denmark, 4University of Copenhagen, Rigshopsitalet, Department of Gastroenterology, Copenhagen, Denmark, 5University of Copenhagen, Frederiksberg Hospital, Department of Internal Medicine, Frederiksberg, Denmark

P597. Adherence to methotrexate (MTX) in inflammatory bowel disease (IBD) patients: an observational multicenter study
Authors:

D. Laharie1, V. Billioud2, X. Roblin3, J. Filippi4, A. Ayroles5, M. Capdepont5, L. Peyrin-Biroulet2, 1CHU de Bordeaux, Gastroentérologie, Pessac, France, 2CHU de Nancy, France, 3CHU de Saint-Etienne, France, 4CHU de Nice, France, 5CHU de Bordeaux, France

P597

The effects of infliximab treatment failure on health-related quality of life and work productivity in patients with Crohn's disease

Authors:

C. Steenholdt*1, J. Brynskov1, O.Ø. Thomsen1, L.K. Munck2, L.A. Christensen3, G. Pedersen4, J. Kjeldsen5, M.A. Ainsworth1

1Herlev Hospital, Dept of Gastroenterology, Herlev, Denmark, 2Køge Hospital, Dept. of Medical Gastroenterology, Køge, Denmark, 3Aarhus Hospital, Dept. of Hepatology and Gastroenterology V, Aarhus, Denmark, 4Hvidovre Hospital, Dept. of Gastroenterology, Hvidovre, Denmark, 5Odense Hospital, Dept. of Medical Gastroenterology S, Odense, Denmark

P598.

Proton pump inhibitor use and risk of microscopic colitis – A nationwide Danish case–control study with 5751 cases

Authors:

O. Bonderup1, T. Wigh2, M. Fenger-Grøn3, G. Lauge Nielsen4, 1Diagnostic Center, Regional Hospital Silkeborg, Denmark, Section of Gastroenterology, Silkeborg, Denmark, 2Regional Hospital Randers, Medical Department, Randers, Denmark, 3Aarhus University, Research Unit for General Practice and Department of Clinical Epidemiology, Aarhus, Denmark, 4Hospital Himmerland, Farsø, Medical Department, Farsø, Denmark

P598. Adalimumab trough levels in a prospective cohort of Crohn's disease patients
Authors:

C.J. van der Woude1, E. Bultman1, J. Deuring1, R. West2, Z. Zelinkova1, M. Peppelenbosch1, 1Erasmus MC, Gastroenterology and Hepatology, Rotterdam, Netherlands, 2St Franciscus hospital, Gastroenterology and Hepatology, Rotterdam, Netherlands

P598

Tuberculosis infection in IBD patients on antitnf therapy: an Algerian retrospective study

Authors:

H. Saoula*1, A. Boutaleb1, T. Bouchelghoum1, N. Ait Hamadouche1, Y. Zmiri1, F. Chemanedji1, M. Aissaoui1, R. Osmane1, D. Hamidouche1, A. Salah1, L. Malaoui1, L. Gamar2, L. Kecili2, N. Bounab2, K. Belhocine2, W. Menni3, N. Kaddache2, F. Yahiaoui3, A. Bousseloub3, N. Zighmi4, T. Hammada4, M. Amar5, C. Hakem5, L. Benahmed5, C. Mamouni5, H. Bouasria5, D. Titsaoui6, T. Douidi6, T. Djadel6, F. Dib7, F. Lounes8, P. Ouldgougam8, S. Cheraitia8, O. Louahadj8, M. Lahcene8, C. Belghazi4, H. Mahiou1, M. Kassama4, T. Boucekkine2, S. Berkane2, M. Nakmouche1

1CHU of Bab El Oued, Gastroenterology, Algiers, Algeria, 2CHU Mustapha, Gastroenterology, Algiers, Algeria, 3HCA, Gastroenterology, Algiers, Algeria, 4CHU Constantine, Gastroenterology, Constantine, Algeria, 5CHU Oran, Gastroenterology, Oran, Algeria, 6CHU Belabbes, Gastroenterology, Belabbes, Algeria, 7CHU Tlemcen, Gastroenterology, Tlemcen, Algeria, 8CHU Bainem, Gastroenterology, Algiers, Algeria

P599.

Prevalence of iron deficiency anemia and iron deficiency in a single center Turkish IBD cohort

Authors:

M. Törüner, C. Kalkan, O. Keskin, H. Cetinkaya, I. Soykan, Ankara University School of Medicine, Department of Gastroenterology, Ankara, Turkey

P599. Adalimumab as first-line anti-TNF treatment in pediatric Crohn's disease
Authors:

J. Martín de Carpi1, E. Llerena1, V. Vila1, S. Pinillos1, V. Varea1, 1Hospital Sant Joan de Déu, Paediatric Gastroenterology, Barcelona, Spain

P599

Adverse efffects in patients with Inflammatory Bowel Disease on biological treatment

Authors:

P. Ramirez de la Piscina*1, L. Urtasun1, I.M. Duca1, K. Spicakova1, I. Ganchegui1, A. Campos1, A. Sanchez1, S. Estrada1, M.D.R. Calderón2, M. Salvador1, E. Delgado1

1HUA- Txagorritxu, Gastroenterology, Vitoria, Spain, 2Hospital de Zumarraga, Gastroenterology, Zumarraga, Spain

P600.

Prevalence of anemia in children with inflammatory bowel disease in Russian Federation

Authors:

A. Anushenko1, A. Potapov1, O. Gordeeva2, E. Tsimbalova3, 1Federal State Budgetary Institution “Scientific Centre of Children Health”, Gastroenterology and Hepatology, Moscow, Russian Federation, 2Federal State Budgetary Institution “Scientific Centre of Children Health”, Clinical Biochemistry, Moscow, Russian Federation, 3Federal State Budgetary Institution “Scientific Centre of Children Health”, gastroenterology and hepatology, Moscow, Russian Federation

P600. A comparison of health related quality of life in IBD patients between nurse-led outpatients clinic and conventional follow-up
Authors:

L. Alvestad1, P.C. Valle1, A.R. Broderstad1, 1University hospital of North Norway, Med. dep. Harstad, Harstad, Norway

P600

Direct and indirect effects of tofacitinib on treatment satisfaction in patients with ulcerative colitis

Authors:

J. Panes*1, C. Su2, A. Bushmakin3, J. Cappelleri3, P. Healey3

1Hospital Clinicas de Barcelona, Department of Gastroenterology, Barcelona, Spain, 2Pfizer Inc, Collegeville, Pennsylvania, United States, 3Pfizer Inc, Groton, Connecticut, United States