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P171
Natural history of perianal Crohn’s disease: long-term follow-up on a population-based cohort
M.-L. Rabilloud1, A.-L. Mallet2, L. Siproudhis2, E. Bajeux3, J.-F. Viel3, I. Tron4, J.-F. Bretagne1, M. Robaszkiewicz5, G. Bouguen*1
1Université Rennes 1 & CHU Pontchaillou Rennes, Service des Maladies de l’Appareil Digestif, Rennes, France, 2Université Rennes 1 & CHU Pontchaillou Rennes, Service de chirurgie digestive, Rennes, France, 3CHU Pontchaillou, Service de Santé Publique, Rennes, France, 4ORSB, Rennes, France, 5CHU Brest, La Cavale Blanche, Service des Maladies de l’Appareil Digestif, Brest, France
P172
Incidence and risk factors of serious viral infections in inflammatory bowel disease
A. Wisniewski*1, 2, C. Landman1, J. Kirchgesner1, A. Bourrier1, I. Nion-Larmurier1, H. Sokol1, P. Seksik1, J. Cosnes1, L. Beaugerie1
1Hôpital Saint-Antoine AP-HP, Department of Gastroenterology and Nutrition, Paris, France, 2Hôpital Charles-Lemoyne, Université de Sherbrooke, Department of Gastroenterology et Hepatology, Montréal, Canada
P173
Comparison of clinical outcomes between young and adult-onset ulcerative colitis: a multicentre KASID study
S.-K. Park*1, J. Y. Kim2, D. S. Han3, K.-C. Huh4, C. K. Lee5, J. E. Shin6, J. H. Kim7, Y. S. Kim8, Y. Jung9, S.-A. Jung10, H. J. Song11, H. J. Jang12, D. I. Park1
1Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea, 2Kangbuk Samsung Hospital, Seoul, South Korea, 3Hanyang University Guri Hospital, Guri, South Korea, 4Konyang University, Daejeon, South Korea, 5Kyung Hee University, Seoul, South Korea, 6Dankook University, Chonan, South Korea, 7Dongguk University, Goyang, South Korea, 8Inje University, Seoul, South Korea, 9Soonchunhyang University, Chonan, South Korea, 10Ewha Woman’s University, Seoul, South Korea, 11Jeju National University, Jeju, South Korea, 12Hallym University, Seoul, South Korea
P174
Capsule endoscopy findings and faecal calprotectin levels predict clinical relapse in patients with quiescent small bowel Crohn’s disease
S. Ben-Horin1, U. Kopylov*2, A. Lahat1, D. Yablecovitch1, S. Neuman1, N. Levhar1, E. Klang3, B. Avidan2, B. Weiss4, H. Yanai5, I. Dotan5, Y. Chowers6, M. M. Amitai3, R. Eliakim2
1Chaim Sheba Medical Centre, Gastroenterology, Ramat Gan, Israel, 2Sheba Medical Centre, Gastroenterology, Tel Hashomer, Israel, 3Sheba Medical Centre, Department of Diagnostic Imaging, Tel Hashomer, Israel, 4Edmond and Lily Safra Children’s Hospital, Gastroenterology, Tel Hashomer, Israel, 5Tel Aviv Medical Centre, IBD Centre, Department of Gastroenterology and Liver Diseases, Tel Aviv, Israel, 6Rambam Health Care Campus, Haifa, Israel; Bruce & Ruth Rappaport School of Medicine, Technion Israel Institute of Technology, Gastroenterology, Haifa, Israel
P175
Rates of colectomy in ulcerative colitis (UC) through time in a Latin Americans unit of inflammatory bowel disease
A. Sambuelli*1, A. Gil1, S. Negreira1, S. Goncalves1, S. Huernos1, M. Bellicoso1, P. Chavero1, P. Tirado1, A. Cabanne2
1IBD Section - Hospital Bonorino Udaondo, Medicine, Buenos Aires, Argentina, 2Hospital Bonorino Udaondo, Pathology Department, Buenos Aires, Argentina
P176
Correlation of biomarkers to simultaneous positron emission tomography with 18F-fluorodeoxyglucose with magnetic resonance imaging enterography and endoscopy for monitoring activity of inflammation in patients with Crohn’s disease
J. Langhorst*1, J. Boone2, A. Rueffer3, G. Dobos4, K. Beiderwellen5, T. Lauenstein6
1University of Duisburg-Essen, Integrative Gastroenterology, Kliniken Essen-Mitte, Essen, Germany, 2Tech Lab Inc, Blacksburg, United States, 3Labor L+S, Enterosan, Bad Bocklet-Grossenbrach, Germany, 4University of Duisburg-Essen, Integrative and Internal Medicine, Essen, Germany, 5University of Duisburg-Essen, Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany, 6University Duisburg-Essen, Department of Diagnostic and Interventional Radiology and Neuroradiology, Essen, Germany
P177
Faecal metalloprotease 9 is a reliable biomarker compared with faecal calprotectin in detecting endoscopic activity in patients with inflammatory bowel diseases.
A. Buisson*1, 2, E. Vazeille1, 2, R. Minet Quinard3, M. Goutte1, 2, D. Bouvier3, F. Goutorbe1, B. Pereira4, N. Barnich2, G. Bommelaer1, 2
1University Hospital Estaing, Gastroenterology Department, Clermont-Ferrand, France, 2UMR 1071 Inserm/Université d’Auvergne; USC-INRA 2018, Microbes, Intestine, Inflammation and Susceptibility of the host, Clermont-Ferrand, France, 3University Hospital G. Montpied, Biochemistry laboratory, Clermont-Ferrand, France, 4GM – Clermont-Ferrand University and Medical Centre, Biostatistics Unit, Clermont-Ferrand, France
P178
Magnetic resonance imaging characteristics of proctitis in Crohn’s disease in correlation with endoscopy
C. Tutein Nolthenius*1, S. Bipat1, B. Mearadji1, A. Spijkerboer1, A. Montauban van Swijndregt2, C. Ponsioen3, J. Stoker1
1Academic Medical Centre (AMC), Radiology, Amsterdam, Netherlands, 2OLVG, Radiology, Amsterdam, Netherlands, 3Academic Medical Centre (AMC), Gastroenterology, Amsterdam, Netherlands
P179
New approach to endoscopic mucosal healing of ulcerative colitis using linked colour imaging, a novel endoscopic enhancement system
K. Uchiyama*, T. Takagi, Y. Toyokawa, Y. Hotta, M. Tanaka, Y. Naito, Y. Itoh
Kyoto Prefectural University of Medicine, Molecular Gastroenterology and Hepatology, Kyoto, Japan
P180
The activity of glutathione peroxidase and superoxide dismutase in the blood serum and saliva in patients with Crohn’s disease
K. Szczeklik1, R. Domagała-Rodacka2, P. Mach3, D. Cibor*2, J. Pytko-Polończyk1, T. Rodacki4, D. Owczarek2
1Jagiellonian University Medical College, Department of Integrated Dentistry, Kraków, Poland, 2Jagiellonian University Medical College, Department of Gastroenterology and Hepatology, Kraków, Poland, 3University of Duisburg-Essen, Department of Gynaecology and Obstetrics, Essen, Germany, 4Jagiellonian University Medical College, Department of Food Chemistry and Nutrition, Kraków, Poland
P181
Accuracy of non-invasive tests in the initial diagnostic work-up of paediatric inflammatory bowel diseases
F. Civitelli*, M. Aloi, A. Dilillo, S. Oliva, L. Stronati, F. Viola, S. Cucchiara
Sapienza University, Paediatric Gastroenterology and Liver Unit, Rome, Italy
P182
Stimulation with chenodeoxycholic acid and meal may increase power of biochemical tests for diagnosis of bile acid diarrhoea
C. Borup*1, S. Wildt2, M. Damgaard3, J. Graff3, P. Nordine Bouchelouche4, D. Rainteau5, J. J. Rumessen6, L. K. Munck7, 8
1Hvidovre University Hospital, Dept. of Medical Gastroenterology, Hvidovre, Denmark, 2Køge University Hospital, Medical Department, Køge-4600, Denmark, 3Hvidovre University Hospital, Clinical Physiology and Nuclear Medicine, Hvidovre, Denmark, 4Køge University Hospital, Clinical Biochemistry, Køge, Denmark, 5Sorbonne University - UPMC, Clinical Biochemistry, Paris, France, 6Gentofte University Hospital, Research Unit, Gentofte, Denmark, 7Køge University Hospital, Medical Department, Køge, Denmark, 8University of Copenhagen, Department of Medical Physiology, Copenhagen, Denmark
P183
Loss of anti-tumour necrosis factor (TNF) drugs into faeces and its impact on anti-TNF serum levels and clinical response in Crohn’s disease patients
M. Chaparro*1, I. Guerra2, L. Bujanda3, J. L. Cabriada4, C. Taxonera5, I. Marín-Jiménez6, P. M. Linares1, M. Ramas1, J. P. Gisbert1
1Hospital Universitario de La Princesa, IIS-IP and CIBERehd, Gastroenterology Unit, Madrid, Spain, 2Hospital Universitario de Fuenlabrada, Gastroenterology Unit, Madrid, Spain, 3Hospital de Donostia, Instituto Biodonostia, UPV/EHU and CIBEREHD, Gastroenterology Unit, Guipuzcoa, Spain, 4Hospital Galdakao, Gastroenterology Unit, Vizcaya, Spain, 5Hospital Clínico Universitario San Carlos and IdISSC, Gastroenterology Unit, Madrid, Spain, 6Hospital Gregorio Marañón and IiSGM, Gastroenterology Unit, Madrid, Spain
P184
A novel automated calprotectin analysis method increases the diagnostic accuracy of the test
T. Lehto*, P. Hedberg, T. Vaskivuo
University of Oulu and Northern Finland Laboratory Centre Nordlab, Oulu, Finland
P185
Capsule endoscopic findings for the diagnosis of Crohn’s disease: a case-control study
M. Esaki*1, T. Matsumoto2, S. Yamamoto3, T. Kinjo4, K. Kinjo5, K. Togashi6, K. Watanabe7, S. Nouda8, S. Ashizuka9, M. Nakamura10, Y. Suzuki11
1Kyushu University, Medicine and Clinical Science, Fukuoka, Japan, 2Iwate Medical University, Internal Medicine, Morioka, Japan, 3University of Miyazaki, Gastroenterology and Hepatology, Miyazaki, Japan, 4University of Ryukyus, Endoscopy, Okinawa, Japan, 5Fukuoka University Chikushi Hospital, Gastroenterology, Chikushino, Japan, 6Aizu Medical Centre, Fukushima Medical University, Coloproctology, Fukushima, Japan, 7Osaka City University, Gastroenterology, Osaka, Japan, 8Osaka Medical College, Second Department of Internal Medicine, Takatsuki, Japan, 9University of Miyazaki, Circulatory and Body Fluid Regulation, Miyazaki, Japan, 10Nagoya University Graduate School of Medicine, Gastroenterology and Hepatology, Nagoya, Japan, 11Toho University, Sakura Medical Centre, Internal Medicine, Chiba, Japan
P186
Does PR3-ANCA positive ulcerative colitis represent a novel subset?
J. LI*1, S. Zhang2, H. Lv1, H. Yang1, Y. Li1, Y. Li2, J. Qian1
1Peking Union Medical College Hospital, Gastroenterology, Beijing, China, 2Peking Union Medical College Hospital, Rheumatology and Clinical Immunology, Beijing, China
P187
Cognitive behavioural profiles from patients on biologics: not what you might think
I. Y. Liew1, G. Chung-Faye1, P. Dubois1, L. Medcalf1, A. Simpson2, J. Hutton2, C. Jordan2, M. Hotopf2, B. Hayee*1
1King’s College Hospital NHS Foundation Trust, Gastroenterology, London, United Kingdom, 2King’s College London, Department of Psychological Medicine, London, United Kingdom
P188
Incidence and clinical features of perianal diseases in patients with ulcerative colitis in Korea
Y. S. Choi*1, W. J. Kim2, J. K. Kim1, K.-H. Song3, H.-J. Jung3
1Daehang Hospital, Gastroenterology, Seoul, South Korea, 2Soonchunhyang University Hospital, Gastroenterology, Gumi-si, South Korea, 3Daehang Hospital, Surgery, Seoul, South Korea
P189
Serial monitoring of faecal calprotectin for the assessment of endoscopic recurrence in asymptomatic patients after ileocolonic resection for Crohn’s disease: a long-term prospective study
T. Yamamoto*, T. Shimoyama, S. Umegae, K. Matsumoto
Yokkaichi Hazu Medical Centre, Inflammatory Bowel Disease Centre, Yokkaichi, Japan
P190
Colonic neuroendocrine carcinoma in ulcerative colitis: a case report
D. Chaaro*1, M. F. Guerra Veloz1, M. B. Maldonado Perez1, L. Castro Laria1, F. Argüelles Arias1, P. Hergueta Delgado1, E. Rodriguez Zarco2, A. Vallejo Benitez2, F. J. Pellicer Bautista1, A. Caunedo Álvarez1
1University Hospital Virgen Macarena, Gastroenterology and Hepatology Department, Seville, Spain, 2University Hospital Virgen Macarena, Pathology Department, Seville, Spain