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P474.

Gut microbiota in patients with inflammatory bowel disease and irritable bowel syndrome before and after 6 weeks of low FODMAP diet

Authors:

N. Pedersen1,2, K. Kofod Vinding3, Z. Vegh4, C. Casen5, N. Andersen6, D. Ankersen6, K. Carlsen6, A. Munk Petersen3, J. Burisch6, P. Munkholm6, 1Herlev University Hospital, Department of Gastroenterology, Copenhagen, Denmark, 2University, Gastroenterology, Copenhagen, Denmark, 3University of Copenhagen, Gastroenterology, Hvidovre, Denmark, 4University of Copenhagen, Gastroenterlogy, Herlev, Denmark, 5Genetic Analysis AS, Genetic, Oslo, Norway, 6University of Copenhagen, Gastroenterology, Herlev, Denmark

P474. Infliximab induction therapy on AA amyloidosis associated with Crohn's disease: case report
Authors:

A. Pukitis1, E. Ostrovskis1, T. Zake2, J. Pokrotnieks2, 1Pauls Stradins Clinical University Hospital, Gastroenterology Center, Riga, Latvia, 2Riga Stradins University, Riga, Latvia

P474

Anti-TNFα treatment efficacy in prevention of postoperative recurrence in Crohn's disease depends on previous exposure to anti-TNFα agents

Authors:

M. Collins*1, H. Sarter2, C. Gower-Rousseau3, D. Koriche4, M. Nachury5, L. Libier5, A. Cortot6, P. Zerbib4, J.-F. Colombel7, L. Peyrin-Biroulet8, P. Desreumaux5, G. Pineton de Chambrun9

1APHP Paris Sud University , Gastroenterology, Le Kremlin Bicêtre, France, 2University and Hospital, Epidemiology, Lille, France, 3Lille University Hospital, North of France University, Epidemiology, Lille, France, 4Lille University Hospital, Colorectal Surgery Department , Lille, France, 5CHU de Lille, Department of Gastroenterology, Lille, France, 6Lille University Hospital, North of France University, Gastroenterology, Lille, France, 7Mount Sinai Hospital, Gastroenterology, New-York, United States, 8Nancy University Hospital, Université de Lorraine, Gastroenterology and Hepatology, Vandoeuvre-les-Nancy, France, 9Montpellier 1 University, Gastroenterology and Hepatology, Montpellier, France

P475.

Granulocyte and Monocyte Apheresis (GMA) – Adacolumn® in mild to moderate ulcerative colitis patients with steroid resistance or dependence and azathioprine intolerance or resistance: a prospective multicenter study (preliminary data)

Authors:

G. Imperiali1, M.M. Terpin2, A. Amato1, A. Bortoli3, G. Meucci4, 1Valduce Hospital, Gastroenterology, Como, Italy, 2Legnano Hospital, Gastroenterology, Legnano, Italy, 3Rho Hospital, Gastroenterology, Rho, Italy, 4S. Giuseppe Hospital, Gastroenterology, Milano, Italy

P475. Infliximab concentration is associated with mucosal healing in intestinal bowel disease (IBD)
Authors:

S. Paul1, E. Del Tedesco1, H. Marotte1, M. Rinaudo-Gaujous1, J.M. Phelip1, L. Peyrin-Biroulet2, X. Roblin1, 1University of Saint Etienne, France, 2Nancy, France

P475

What is our success on complex perianal fistulae healing under optimal medical treatment ending up with ileostomy?

Authors:

Y. Erzin*1, A. Ercaliskan1, I. Hatemi1, B. Baca2, N. Demir1, K. Bal1, A.F. Celik1

1Istanbul University Cerrahpasa Medical Faculty, Gastroenterology, Istanbul, Turkey, 2Istanbul University Cerrahpasa Medical Faculty, General Surgery, Istanbul, Turkey

P476.

Gender specific differences in quality of life in Danish paediatric patients with inflammatory bowel disease

Authors:

K. Carlsen1,2, C. Jakobsen1, L.F. Hansen1, A. Paerregaard1, V. Wewer1, P. Munkholm2, 1Copenhagen University Hospital, Department of Paediatrics, Hvidovre, Denmark, 2Copenhagen University Hospital, Department of Gastroenterology, Herlev, Denmark

P476. Induction therapy with infliximab in children with moderate to severe ulcerative colitis
Authors:

M. Szychta1, M. Dadalski1, P. Landowski2, B. Klincewicz3, M. Sladek4, K. Karolewska-Bochenek5, G. Czaja-Bulsa6, E. Jarocka-Cyrta7, B. Korczowski8, J. Kierkus1, 1The Children's Memorial Health Institute, Department of Gastroenterology, Hepatology and Feeding Disorders, Warsaw, Poland, 2Medical University of Gdansk, Chair and Department of Pediatrics, Pediatric Gastroenterology, Hepatology and Nutrition, Gdansk, Poland, 3Poznan University of Medical Sciences, 1st Chair of Pediatrics, Department of Pediatric Gastroenterology and Metabolism, Poznan, Poland, 4Jagiellonian University School of Medicine, Department of Pediatrics, Gastroenterology and Nutrition, Cracow, Poland, 5Medical University of Warsaw, Department of Pediatric Gastroenterology and Nutrition, Warsaw, Poland, 6Pediatric Nursery Unit of Pomeranian Medical University, Division of Pediatrics, Gastroenterology and Rheumatology of Zdroje Hospital in Szczecin, Szczecin, Poland, 7Medical University of Bialystok, Department of Pediatrics, Gastroenterology and Allergology, Bialystok, Poland, 8Medical College. University of Rzeszow, Department of Pediatrics. State Hospital no 2, Rzeszow, Poland

P476

EArly SurgerY or Immunosuppression - EASY study

Authors:

F. Magro*1, R. Coelho1, S. Fernandes2, A. Rodrigues3, A. Oliveira4, P. Sousa5, R. Barosa6, P. Boal Carvalho7, D. Trabulo8, M. Eusébio9, J. Moleiro10, R. Herculano11, P. Peixe11, B. Gonçalves12, H. Morna13, H. Tavares14, L. Contente14, R. Gonçalves12, P. Caldeira9, I. Rosa10, I. Cremers8, J. Cotter7, A. Vieira6, P. Ministro5, F. Portela4, C. Caetano3, P. Moura-Santos2, S. Lopes1, C. Camila-Dias15

1Centro Hospitalar São João, Gastrenterology, Porto, Portugal, 2Hospital de Santa Maria , Gastrenterology, Lisboa, Portugal, 3Centro Hospitalar do Porto, Gastrenterology, Porto, Portugal, 4Centro Hospitalar e Universitário de Coimbra, Gastrenterology, Coimbra, Portugal, 5Centro Hospitalar Tondela- Viseu, Gastrenterology, Viseu, Portugal, 6Hospital Garcia de Orta, Gastrenterology, Almada, Portugal, 7Centro Hospitalar do Alto Ave, Gastrenterology, Guimarães, Portugal, 8Centro Hospitalar de Setúbal, Gastrenterology, Setúbal, Portugal, 9Hospital de Faro , Gastrenterology, Faro, Portugal, 10Instituto Português de Oncologia de Lisboa, Gastrenterology, Lisboa, Portugal, 11Centro Hospitalar de Lisboa Ocidental, Gastrenterology, Lisboa, Portugal, 12Hospital de Braga, Gastrenterology, Braga, Portugal, 13Hospital Dr. Nélio Mendonça, Gastrenterology, Funchal, Portugal, 14Centro Hospitalar do Barlavento Algarvio, Gastrenterology, Portimão, Portugal, 15University of Porto, CIDES-Department of Health Information and Decision Sciences, Faculty of Medicine, Porto, Portugal

P477.

Fecal calprotectin reflects mucosal healing in ulcerative colitis

Authors:

D.B. Kim1, K.-M. Lee1, Y.W. Lee1, S.H. Jung2, J.M. Lee1, Y.Y. Chung1, W.C. Chung1, 1St. Vincent's Hospital, The Catholic University of Korea, Internal Medicine, Suwon, South Korea, 2St. Paul's Hospital, The Catholic University of Korea, Internal Medicine, Seoul, South Korea

P477. Increased risk of comorbidities associated with ulcerative colitis
Authors:

T. Ali1, M. Skup2, M. Yang2, J. Chao2, P.M. Mulani2, 1University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States, 2Abbott Laboratories, Abbott Park, IL, United States

P477

Biological Therapy Is Able To Modify The Disease Progression of Crohn's Disease Preventing Its Long-Term Associated Disability - A Study Performed By Using The Lèmann Score

Authors:

G. Bodini*1, V. Savarino1, I. Baldissarro1, C. De Maria1, L. Yehia1, E. Savarino1, 2

1IRCCS San Martino Genova, Dipartimento di medicina interna, Genova, Italy, 2University of Padua, Department of Surgery, Oncology and Gastroenterology, padova, Italy

P478.

Feasibility and utility of a lactoferrin twice weekly monitoring in patients with ulcerative colitis

Authors:

J. Langhorst1, M. Schöls1, A. Rüffer2, G.J. Dobos3, J.H. Boone4, 1University Duisburg-Essen, Kliniken Essen-Mitte, Integrative Gastroenterology, Essen, Germany, 2Labor L+S, Enterosan, Bad Bocklet-Großenbrach, Germany, 3University Duisburg-Essen, Kliniken Essen-Mitte, Internal and Integrative Medicine, Essen, Germany, 4TechLab Inc., Virginia, Blacksburg, United States

P478. Increased activity of inflammatory bowel disease after liver transplantation for primary sclerosing cholangitis
Authors:

K.K. Jørgensen1, L. Lindström2, M. Cvancarova3, T.H. Karlsen1, M. Castedal4, S. Friman4, E. Schrumpf1, A. Foss5, H. Isoniemi6, A. Nordin6, K. Holte7, A. Rasmussen7, A. Bergquist2, M.H. Vatn1, K.M. Boberg1, 1Oslo University Hospital, Rikshospitalet, Section for Gastroenterology, Oslo, Norway, 2Karolinska University Hospital, Department of Gastroenterology and Hepatology, Stockholm, Sweden, 3University of Oslo, Department of Biostatistics, Oslo, Norway, 4Sahlgrenska University Hospital, The Transplant Institute, Gothenburg, Sweden, 5Oslo University Hospital, Rikshospitalet, Section for Transplantation Surgery, Oslo, Norway, 6Helsinki University Hospital, Transplantation and Liver Surgery Clinic, Helsinki, Finland, 7University of Copenhagen, Rigshospitalet, Department of Surgical Gastroenterology and Liver Transplantation, Copenhagen, Denmark

P478

Vitamin D status and response to anti-tumor necrosis factor-alpha therapy in inflammatory bowel disease

Authors:

N.F. Bak*1, S. Hald1, M.B. Rasch1, A. Dige2, J.S. Agnholt1, J.F. Dahlerup1

1Aarhus University Hospital, Department of Hepatology and Gastroenterology, Aarhus, Denmark, 2Regional Hospital Horsens, Department of Medicine, Horsens, Denmark

P479.

Feasibility and utility of a web-based self-reporting symptoms diary of Crohn's disease

Authors:

E.S. Kim1, K.B. Cho1, B.I. Jang2, S.W. Jeon3, M.K. Jung3, E.Y. Kim4, K.O. Kim2, K.S. Park1, C.H. Yang5, 1Keimyung University School of Medicine, Internal Medicine, Daegu, Korea, Republic of, 2Yeungnam University College of Medicine, Internal Medicine, Daegu, Korea, Republic of, 3Kyungpook National University School of Medicine, Internal Medicine, Daegu, Korea, Republic of, 4Catholic University of Daegu School of Medicine, Internal Medicine, Daegu, Korea, Republic of, 5Dongguk University College of Medicine, Division of gastroenterology and Hepatology, department of Internal Medicine, Kyungju, Korea, Republic of

P479. In carefully selected ulcerative colitis patients the failure rate after ileorectal anastomosis does not seem to differ from ileal-pouch anal anastomosis
Authors:

P. Myrelid1, R. Norblad2, J.D. Söderholm2, P. Andersson2, 1Linköping University Hospital, Dept of Surgery, Linköping, Sweden, 2Linköping University Hospital, Dept of Surgery, Colorectal Unit, Linköping, Sweden

P479

Factors Associated with Development of Endoscopic Stricture in Patients with Crohn's Disease Treated with Infliximab

Authors:

T. Feng*1, B.-l. Chen1, R. Mao1, M. Li1, P. Rao1, Z.-r. Zeng1, P. Hu2, M.-h. Chen1

1First Affiliated Hospital of Sun Yat-Sen University, Department of Gastroenterology, Guangzhou, China, 2Sixth Affiliated Hospital of Sun Yat-Sen University, Department of Gastroenterology, Guangzhou, China

P480.

Fast, safe and effective treatment of iron deficiency (ID) of different aetiologies using iron isomaltoside 1000 – experience from clinical practice

Authors:

L. Craven1, J. Snook1, S. Surgenor1, U. Bapat2, C. Strom3, E. Williams1, 1Poole Hospital NHS Foundation Trust, Gastroenterology, Poole, United Kingdom, 2Pharmacosmos UK Ltd, Pharmacosmos UK, Thame, United Kingdom, 3Pharmacosmos, Medical Affairs, Holbaek, Denmark

P480. Importance of diet in inflammatory bowel disease – data from the patients' view
Authors:

T. Molnár1, K. Farkas1, F. Nagy1, M. Szücs2, A. Bálint1, Z. Szepes1, T. Wittmann1, 1University of Szeged, First Department of Medicine, Szeged, Hungary, 2University of Szeged, Department of Medical Physics and Informatics, Szeged, Hungary