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P457

Anti-TNF therapy successfully improves anemia in Inflammatory Bowel Disease - Results from a tertiary referral center

Authors:

M. Moura*, S. Fernandes, P. Sousa, P. Santos, C. Baldaia, A.R. Gonçalves, A. Valente, P. Moura Santos, L. Correia, F. Serejo, J. Velosa

Hospital de Santa Maria - CHLN, Serviço de Gastrenterologia e Hepatologia, Lisboa, Portugal

P458.

Impact of concomitant immunosuppressant use on adalimumab efficacy in children with moderately to severely active Crohn's disease: Results from IMAgINE 1

Authors:

J. Hyams1, F. Ruemmele2, R. Colletti3, J. Kierkus4, J. Rosh5, S. Eichner6, A. Lazar7, Y. Li6, R.B. Thakkar6, 1Connecticut Children's Medical Center, Division of Digestive Diseases, Hartford, United States, 2Universite Sorbonne Paris-Cite, Hospital Necker-Enfants Malades, APHP, Paris, France, 3University of Vermont, Department of Pediatrics, Burlington, United States, 4The Children's Memorial Health Institute, Gastroenterology, Hepatology and Feeding Disorders, Warsaw, Poland, 5Goryeb Children's Hospital/Atlantic Health, Pediatric Gastroenterology, Morristown, United States, 6AbbVie Inc, GPRD, North Chicago, United States, 7AbbVie Deutschland GmbH & Co, KG, GPRD, Ludwigshafen, Germany

P458. Long-term efficacy and safety of adalumumab in patients with Crohn's disease naïve to prior anti-TNFa therapy compared to prior infliximab failures
Authors:

K. Papamichael1, E. Archavlis1, P. Konstantopoulos1, N. Kyriakos1, D. Tsironikos1, I. Drougas1, X. Tzanetakou1, I. Internos1, S. Anastasiadis1, P. Karatzas1, G. Mantzaris1, 1Evangelismos Hospital, Athens Greece, A' Department of Gastroenterology, Athens, Greece

P458. The microbiota in Crohn's disease and health – is it the same in the East and West? The effects of geography, ethnicity and disease on microbiota
P458

Cutaneous events during anti-tumour necrosis factor (anti-TNF) treatment at a London Inflammatory Bowel Disease (IBD) centre

Authors:

C. Lim*1, T. Shepherd2, E. Cronin2, K. Greveson2, M. Hamilton2, C. Murray2

1UCL, Gastroenterology , London, United Kingdom, 2Royal Free London NHS Foundation Trust, Department of Gastroenterology, London, United Kingdom

P459.

Impact of inflammatory bowel disease on patients' daily life: An online Korean Association for the Study of Intestinal Disease (KASID) survey

Authors:

Y.S. Kim1, S.A. Jung2, K.M. Lee3, S.J. Park4, T.O. Kim5, C.-H. Choi6, H.G. Kim7, W. Moon8, C.M. Moon9, H.K. Song2, S.-Y. Na10, S.-K. Yang11, 1Seoul National University Hospital Healthcare System Gangnam center, Internal Medicine, Seoul, Korea, Republic of, 2Ewha University school of Medicine, Internal Medicine, Seoul, Korea, Republic of, 3The Catholic University College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 4Yonsei University College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 5Haeundae Paik Hospital, Inje University College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 6Chung-Ang University College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 7Soonchunhyang University College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 8Kosin University College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 9Kangbuk Samsung Hospital, Sungkyunkwan University College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 10Jeju National University School of Medicine, Internal Medicine, Seoul, Korea, Republic of, 11Ulsan University College of Medicine, Internal Medicine, Seoul, Korea, Republic of

P459. Is preoperative use of biologics in abdominal surgery with bowel anastomosis for Crohn's disease safe?
Authors:

P. Myrelid1, M. Marti-Gallostra2, S. Ashraf3, M.L. Sunde4, T. Øresland4, V. Robles5, M. Tholin1, R. Lovegrove3, D. Humes6, A. Tøttrup7, D. Kjaer7, B. George3, 1Linköping University Hospital, Dept of Surgery, Linköping, Sweden, 2University Hospital of Valle de Hebron, Colorectal Surgery, Barcelona, Spain, 3Oxford University Hospitals, Colorectal Surgery, Oxford, United Kingdom, 4Akershus University Hospital, Dept of Surgery, Oslo, Norway, 5University Hospital of Valle de Hebron, Gastroenterology, Barcelona, Spain, 6Nottingham University Hospitals, Dept of Surgery, Nottingham, United Kingdom, 7Aarhus University Hospital, Dept of Gastroenterological Surgery, Aarhus, Denmark

P459. Predominant dysbiosis in patients with ulcerative colitis is different from Crohn's disease patients
P459

Characteristics of Pediatric Crohn's Disease in a Tertiary Center in China according to Paris Classification

Authors:

K. Chao*, X. Gao, J. Guo, N. Ding, M. Zhi, P. Hu

The Sixth Affiliated Hospital, Sun Yat-sen Universtity, Gastroenterolgy and Hepatology, Guangzhou, China

P460.

Immune responses and safety of intramuscular or intradermal trivalent influenza vaccines in patients with inflammatory bowel disease: a randomized controlled trial

Authors:

W.K. Leung1, T. Tong1, K.H. Chan2, C. Li2, V. Tan1, I. Hung1, 1University of Hong Kong, Department of Medicine, Hong Kong, Hong Kong, 2Queen Mary Hospital, Department of Microbiology, Hong Kong, Hong Kong

P460. Is it necessary to perform x-ray absorptiometry in young IBD patients to predict the risk of fracture?
Authors:

K. Lorinczy1, P.L. Lakatos2, Á. Salamon3, A. Nemes3, T. Pere3, Á. Csontos1, B. Fekete1, O. Terjék1, L. Herszényi1, Z. Tulassay1, P. Miheller1, 1Semmelweis University, 2nd Department of Internal Medicine, Budapest, Hungary, 2Semmelweis University, 1nd Department of Internal Medicine, Budapest, Hungary, 3János Balassa Tolna County Hospital, Department of Gastroenterology, Szekszárd, Hungary

P460. Ulcerative colitis patients and the patients' relative enterobacteria Bush comparative investigation
P460

Efficacy and Safety of Granulocyte/Monocyte Apheresis in Active Ulcerative Colitis Using an Adsorber Device Based on Cellulosic Filaments

Authors:

C. Sauvant1, C. Schultheiss2, W. Huber2, W. Ramlow3, J. Emmrich4, F. Bonn*5, H.-D. Lemke1

1eXcorLab GmbH, R & D, Obernburg, Germany, 2Klinikum rechts der Isar, Technical University Munich, Medicine II, Munich, Germany, 3Dialysis Group North, Apheresis Center, Rostock, Germany, 4University of Rostock, Gastroenterology, Rostock, Germany, 5Membrana GmbH, New Business, Wuppertal, Germany

P461.

Influence of melatonin on the course of ulcerative colitis

Authors:

A. Dorofeyev, O. Rassokhina, National Medical University, Chair Internal Medicine #2, Donetsk, Ukraine

P461. Analysis of the mucosal microbiota from inflammatory bowel disease biopsy tissues using a custom 16s rRNA based phylogenetic microarray
P461. Is laparoscopy safe and useful in patients with acute colitis complicating inflammatory bowel disease? A first meta-analysis in 478 patients
Authors:

L. Maggiori1, A. Khayat1, X. Tréton2, F. Bretagnol1, Y. Bouhnik2, Y. Panis1, 1Hôpital Beaujon, Colorectal surgery, Clichy, France, 2Hôpital Beaujon, Gastroenterology & Nutritive Assistance, Clichy, France

P461

Therapeutic requirements and health resources in the treatment of clinically active ulcerative proctitis

Authors:

C. Margalida*, M. Larrain, N. Caballero, M. Mañosa, T. Labaton, L. Marin, E. Cabre, E. Domenech

Hospital Universitari Germans Trias i Pujol and CIBERehd, Gastroenterology, Badalona, Spain

P462.

Influence of immunosuppressant treatment on the development and progression of neoplasms in patients with inflammatory bowel disease

Authors:

G. Ontanilla Clavijo, E. Leo Carnerero, C. Trigo Salado, M.D. De La Cruz Ramirez, A. Araujo Miguez, J.M. Herrera Justiniano, J.L. Marquez Galan, HU Virgen del Rocío, UGC Digestive Diseases, Seville, Spain

P462. Iron deficiency anemia in pediatric Crohn's disease: preliminary evaluation of parenteral iron therapy
Authors:

M. Valente Pinto1, S. Azevedo1, H. Loreto1, P. Mourato1, C. Maltez1, A.I. Lopes1, 1Academic Medical Center of Lisboa, Pediatric Department – Santa Maria Hospital – CHLN, Lisboa, Portugal

P462. Terminal restriction fragment length polymorphism analysis of the diversity of fecal microbiota in patients with inflammatory bowel disease