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P417. Nosocomial Clostridium difficile infection (CDI) incidence in two Spanish referral hospitals. Secular trend during the last decade
P417

Ileal pouch-anal anastomosis for dysplasia or cancer complicating inflammatory bowel disease: should a total mesorectal excision always be performed? An analysis of 39 consecutive patients.

Authors:

L. Maggiori*1, C. Coton1, X. Tréton2, Y. Bouhnik2, Y. Panis1

1Beaujon Hospital, Colorectal Surgery, Clichy, France, 2Beaujon Hospital, Gastroenterology, Clichy, France

P418.

Low dose naltrexone in therapy resistant IBD, a case series

Authors:

M. Lie, G. Fuhler, A. de Lima, C. van der Ent, C.J. van der Woude, Erasmus Medical Center, Gastroenterology and Hepatology, Rotterdam, Netherlands

P418. Extraintestinal manifestations in inflammatory bowel disease; the prevalence in tertiary referral center
P418. Magnetic resonance enterography demonstrates response to anti-TNF therapy in small bowel Crohn's disease
Authors:

R. Dart1,2, N. Griffin3, V. Goh3, K. Taylor1,2, S. Anderson1, J. Sanderson1,2, P. Irving1,2, 1St Thomas' Hospital, Department of Gastroenterology, London, United Kingdom, 2King's College, University of London, Nutritional Sciences Division, United Kingdom, 3St Thomas' Hospital, Department of Radiology, London, United Kingdom

P418

Looking beyond the mucosa: transmural healing after one-year anti-TNFα therapy in Crohn's disease

Authors:

M. Serio*1, K. Efthymakis1, A. Pierro2, A. Milano1, F. Laterza1, G. Maselli2, A. Bonitatibus1, R. De Prophetis1, G. Sallustio2, M. Neri1

1Università "G. D'Annunzio", Medicine and Aging Sciences and CESI, Chieti, Italy, 2Fondazione di Ricerca e Cura "Giovanni Paolo II", Università Cattolica del Sacro Cuore, Radiology Department, Campobasso, Italy

P419.

Low dose azathioprine and allopurinol in azathioprine intolerant patients: is it tolerated and is it effective in IBD?

Authors:

H. Johnson, S. Weaver, S. McLaughlin, Royal Bournemouth Hospital, Gastroenterology, Bournemouth, United Kingdom

P419. Isotretinoin use and risk of inflammatory bowel disease: A case–control study from the French national health insurance system
P419. Patient's awareness of the need for vaccinations whilst on immunosuppressive therapy
Authors:

M. Widlak1, R. Matharu1, A. Elzubeir1, J. Slater1, L. Wood1, S. De Silva1, 1Russells Hall Hospital, Gastroenterology, Dudley, United Kingdom

P419

Rapid Changes in Laboratory Parameters and Early Response to Adalimumab: Pooled Analysis from ULTRA 1 and ULTRA 2

Authors:

S. Hanauer*1, W.J. Sandborn2, J.-F. Colombel3, W. Reinisch4, 5, S. Vermeire6, J. Petersson7, B. Pappalardo7, A.M. Robinson7, A. Lazar8, Q. Zhou7, R.B. Thakkar7

1Northwestern University Feinberg School of Medicine, Digestive Health Centre, Chicago, United States, 2University of California San Diego, Division of Gastroenterology , La Jolla, United States, 3Icahn School of Medicine at Mount Sinai, Gastroenterology, New York City, United States, 4McMaster University, Gastroenterology, Hamilton, Canada, 5Medical University of Vienna, Dept. for Gastroenterology and Hepatology, Vienna, Austria, 6University Hospital Leuven, Gastroenterology, Leuven, Belgium, 7AbbVie Inc., Global Pharmaceutical Research & Development, North Chicago, United States, 8AbbVie Deutschland GmbH & Co, KG, GPRD, Ludwigshafen, Germany

P420.

Low dose azathioprine and allopurinol co-therapy: is it safe to use without metabolite monitoring?

Authors:

B. Eross, H. Johnson, S. Weaver, S. McLaughlin, Royal Bournemouth Hospital, Gastroenterology, Bournemouth, United Kingdom

P420. Parietal healing in patients with Crohn's disease on maintenance treatment with biologics
Authors:

A. Rispo1, A. Testa1, M. Rea1, G.D. De Palma2, M. Diaferia1, D. Musto1, F. Sasso1, M. Tramontano1, N. Caporaso1, F. Castiglione1, 1University Federico II Of Naples, Gastroenterology, Naples, Italy, 2University Federico II Of Naples, Surgery and Advanced Technologies, Naples, Italy

P420. The clinical characteristics at diagnosis and course of Crohn's disease: A Korean multicenter study
P420

Thiopurine metabolite testing to guide management in inflammatory bowel disease (IBD) yields clinical benefit at 12 months: A retrospective observational study.

Authors:

S.-Y.J. Ooi1, M. Gounder2, R. Grafton1, P. Leach3, A. Sechi2, W. Ng2, S. Connor2, P. Bampton3, J.M. Andrews*1

1Royal Adelaide Hospital, Gastroenterology and Hepatology, Adelaide, Australia, 2Liverpool Hospital, Gastroenterology & Hepatology, Liverpool, Australia, 3Flinders Medical Centre, Inflammatory Bowel Disease Service, Bedford Park, Australia

P421.

Long term results of infliximab treatment of fistulas in patients with Crohn's disease in Arctic Norway

Authors:

R. Heitmann, R. Goll, J.R. Florholmen, University of Tromsø, The Arctic University of Norway, Department of Clinical Medicine, Tromsø, Norway

P421. Epidemiological study of occurrence, clinical course and treatment options of IBD in Serbia. Results of ESCApe study
P421. Prevalence of steroid dependence and resistance in inflammatory bowel disease patients: treatment options as steroid-sparing agents in a single centre
Authors:

C. Cassieri1, A. De Carolis1, R. Pica1, E.V. Avallone1, M. Zippi1, C. Corrado1, E.S. Corazziari1, P. Vernia1, P. Paoluzi1, 1Sapienza University, Internal Medicine and Medical Specialties, “Gastroenterology Unit”, Rome, Italy

P421

Transitional care in Inflammatory Bowel Disease - a single center experience

Authors:

Y. Ron*1, A. Yerushalmy-Feler2, A. Nachum3, I. Dotan1, S. Cohen2

1Tel Aviv Sourasky Medical Center, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, IBD Center, Department of Gastroenterology and Liver Diseases, Tel Aviv, Israel, 2"Dana-Dwek" Children's Hospital, affiliated to the Sackler Faculty of Medicine, Tel Aviv University, The Pediatric Gastroenterology unit, Tel Aviv, Israel, 3Tel Aviv Sourasky Medical Center , Health and Medical Psychological service, Tel Aviv, Israel

P422.

Long term outcomes from leucocytapheresis in ulcerative colitis: A retrospective case series from a large UK centre

Authors:

P. Harrow, H. Kwok, G. Parkes, P. Premchand, Queen's Hospital, Gastroenterology, Romford, United Kingdom

P422. Outpatient anal exploration and fistula treatment in Crohn's disease patients with peri-anal disease. Study of feasibility
Authors:

R. Scaramuzzo1, E. Iaculli2, C. Fiorani3, L. Biancone1, T. Giorgia3, D.C. Sara3, A. Gaspari3, G. Sica3, 1Tor Vergata, Italy, 2Guy's and St Thomas' Hospital, Surgery, London, United Kingdom, 3Tor Vergata Roma, Italy