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P407. Predictive factors for the efficacy of leukocytapheresis in ulcerative colitis
Authors:

K. Mitsuyama1, K. Nagayama1, H. Takedatsu1, T. Kobayashi1, H. Yamasaki1, K. Kuwaki1, S. Yoshioka1, O. Tsuruta1, M. Sata1, 1Kurume University School of Medicine, Division of Gastroenterology, Department of Medicine, Kurume, Japan

P407

Prevalence of methotrexate intolerance in pediatric inflammatory bowel disease

Authors:

C. Dupont-Lucas1, C. Grandjean-Blanchet*1, C. Larocque1, P. Jantchou1, 2, D. Amre1, 2, C. Deslandres1

1CHU Sainte Justine, Pediatric gastroenterology, Montreal, Canada, 2Saint Justine Medical Center, Research Institute, Montreal, Canada

P408.

Motivational interviewing in inflammatory bowel disease patients: a useful tool during outpatient counselling

Authors:

F. Mocciaro1, R. Di Mitri1, G. Russo1, S. Sferrazza1, S. Leone2, V. Quercia3, 1ARNAS Civico-Di Cristina-Benfratelli Hospital, Gastroenterology and Endoscopy Unit, Palermo, Italy, 2CEO of AMICI onlus, AMICI onlus, Palermo, Italy, 3Social Worker, MINT (Motivational Interviewing Network of Trainer), Rome, Italy

P408. Prediction of clinical responders to treatment with DIMS0150 a Toll-Like Receptor 9 agonist in therapy refractory ulcerative colitis patients
Authors:

O. von Stein1, E. Musch2, R. Löfberg3, N. Kuznetsov1, P. von Stein1, 1InDex Pharmaceuticals, Stockholm, Sweden, 2Marienhospital, Clinic of Colo-Proctology, Bottrop, Germany, 3IBD unit Sophiahemmet and the Dept of Medicine, Karolinska Institutet, Stockholm, Sweden

P408. Safety of immunomodulators and anti‑TNF drugs for the treatment of inflammatory bowel disease (IBD) during pregnancy
P408

Differences in biologic efficacy and dose-escalation among anti-TNF agents in Crohn´s disease and ulcerative colitis

Authors:

A. Echarri*1, P. López-Casado2, R. Fraga1, V. Ollero1, L. García-Dieguez1

1Complejo Hospitalario Ferrol, Gastroenterology, Ferrol, Spain, 2Universidad de Valladolid, Estadística, Valladolid, Spain

P409.

More targeted evaluation of nutrition in inflammatory bowel disease (IBD) reveals opportunities to optimise care: body mass index, body composition and iron deficiency

Authors:

S.-Y. Ooi1, R. Bryant1, C. Schultz2, C. Goess1, R. Grafton1, J. Hughes1, J. McMahon1, D. Bartholomeusz1, J. Andrews1, 1Royal Adelaide Hospital, Gastroenterology and Hepatology, Adelaide, Australia, 2Royal Adelaide Hospital, Department of Nuclear Medicine, Adelaide, Australia

P409. Immunity to varicella zoster in IBD patients treated with TNF inhibitors
P409. Physician knowledge of reproductive issues in inflammatory bowel disease is highly variable
Authors:

V. Huang1, K. Kroeker2, K. Goodman2, L. Dieleman2, R. Fedorak2, 1University of Alberta, Edmonton, Canada, 2University of Alberta, Canada

P409

Smoking is associated with extra-intestinal manifestations in inflammatory bowel disease

Authors:

M. Severs*1, S. van Erp2, G. Dijkstra3, M.E. van der Valk1, M.-J. Mangen4, M. van der Have1, A.A. van Bodegraven5, 6, H.H. Fidder1, D.J. de Jong7, M. Pierik8, J. van der Woude9, M.J.L. Romberg- Camps5, C.H.M. Clemens10, J.M. Jansen11, P.C. van de Meeberg12, N. Mahmmod13, C.Y. Ponsioen14, C.J. Bolwerk15, J.R. Vermeijden16, P.D. Siersema1, M. Leenders1, A.E van der Meulen- de Jong2, B. Oldenburg1

1University Medical Centre Utrecht, Gastroenterology and Hepatology, Utrecht, Netherlands, 2Leiden University Medical Centre, Gastroenterology and Hepatology, Leiden, Netherlands, 3University Medical Centre Groningen, Gastroenterology and Hepatology, Groningen, Netherlands, 4University Medical Centre Utrecht, Julius center for health sciences and primary care, Utrecht, Netherlands, 5ORBIS medical center, Gastroenterology and Hepatology, Sittard, Netherlands, 6VU medical center, Gastroenterology and Hepatology, Amsterdam, Netherlands, 7University Medical Center st. Radboud, Gastroenterology and Hepatology, Nijmegen, Netherlands, 8University Medical Center Maastricht, Gastroenterology and Hepatology, Maastricht, Netherlands, 9Erasmus Medical Center, Gastroenterology and Hepatology, Rotterdam, Netherlands, 10Diaconessenhuis, Gastroenterology and Hepatology, Leiden, Netherlands, 11Onze Lieve Vrouwe Gasthuis, Gastroenterology and Hepatology, Amsterdam, Netherlands, 12Slingeland Hospital, Gastroenterology and Hepatology, Doetinchem, Netherlands, 13Antonius Hospital, Gastroenterology and Hepatology, Nieuwegein, Netherlands, 14Academic Medical Centre Amsterdam, Gastroenterology and Hepatology, Amsterdam, Netherlands, 15Reinier de Graaf Groep, Gastroenterology and Hepatology, Delft, Netherlands, 16Meander Medical Centre, Gastroenterology and Hepatology, Amersfoort, Netherlands

P410.

Microbiota profiling in PSC and control patients: A pilot study

Authors:

N. Rossen1, S. Fuentes2, K. Boonstra1, G. D'Haens1, H. Heilig2, E. Zoetendal2, W. de Vos2, C. Ponsioen1, 1Academic Medical Center, Gastroenterology & Hepatology, Amsterdam, Netherlands, 2Wageningen University, Laboratory of Microbiology, Wageningen, Netherlands

P410. Incidence rates and disease course of pediatric IBD in Western Hungary between 1977–2008
P410. Physician-initiated treatment patterns of ulcerative colitis patients in the United Kingdom: a review of chart-abstracted data
Authors:

L. Yen1, B.J. Katic1, 1Shire Development LLC, Wayne, PA, United States

P410

Anti-TNF improves iron availability in Inflammatory Bowel Diseases, modulating Pro-hepcidin in an Erythroferrone-independent fashion

Authors:

F. Cavallaro*1, L. Pastorelli1, 2, L.F. Pisani1, L. Duca3, 4, R. Rigolini5, L. Spina1, G.E. Tontini1, N. Munizio1, E. Costa5, M.D. Cappellini3, 4, M. Vecchi1, 2

1IRCCS Policlinico San Donato, Gastroenterology and Gastrointestinal Endoscopy Unit, San Donato Milanese, Italy, 2University of Milan, Department of Biomedical Sciences for Health, Milan, Italy, 3University of Milan, Department of Clinical Sciences and Community, Milan, Italy, 4IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Internal Medicine, Milan, Italy, 5IRCCS Policlinico San Donato, Operative Unit of Laboratory Medicine, San Donato Milanese, Italy

P411.

Meta-analysis of the efficacy of a second-line anti-TNF in inflammatory bowel disease patients with failure to a previous anti-TNF treatment

Authors:

J.P. Gisbert, A. Marín, A. McNicholl, M. Chaparro, Hospital Universitario de La Princesa, IP and CIBERehd, Gastroenterology Unit, Madrid, Spain

P411. Is smoking still an important environmental factor in inflammatory bowel diseases? Results from a population-based incident cohort
P411. Pharmacokinetics of adalimumab in pediatric patients with moderate to severe Crohn's disease
Authors:

D. Eckert1, S. Mensing1, S. Sharma2, R. Thakkar2, A. Robinson2, J. Hyams3, J. Rosh4, F.M. Ruemmele5, W. Awni2, 1Abbott Laboratories, Germany, 2Abbott Laboratories, United States, 3Connecticut Children's Med Ctr, United States, 4NJ Medical School, United States, 5Hôpital Necker-Enfants Malades, France

P411

Five year outcomes of Crohn's anastamotic strictures treated with balloon dilatation

Authors:

N.S. Ding*1, W. Yip1, M. Hanna1, B. Saunders2, S. Thomas-Gibson2, A. Humphries2, A. Hart1

1St Mark's Hospital, Inflammatory Bowel Disease Unit, London, United Kingdom, 2St Mark's Hospital, Department of IBD, Colorectal Surgery and Wolfson Unit of Endoscopy, London, United Kingdom

P412.

Medication adherence in patients with active Crohn's disease: results from a large Italian multicenter survey

Authors:

A. Orlando1, M. Principi2, M.L. Scribano3, G. Delle Fave4, P. Vernia5, P. Usai6, F. Castiglione7, G. Bodini8, A.F. Ciccaglione9, L. Biancone10, S. Saettone11, A. Michielan12, A. Iezzi13, A.C. Privitera14, 1Ospedali Riuniti Villa Sofia Cervello, Internal Medicine, Palermo, Italy, 2University of Bari, Gastroenterology, Bari, Italy, 3Azienda Ospedaliera San Camillo-Forlanini, Gastroenterology, Rome, Italy, 4Ospedale S. Andrea, Gastroenterology, Rome, Italy, 5University “La Sapienza”, Gastroenterology, Rome, Italy, 6University of Cagliari, Gastroenterology, Cagliari, Italy, 7University “Federico II”, Gastroenterology, Naples, Italy, 8Ospedale San Martino, Gastroenterology, Genoa, Italy, 9Ospedale Civile “S. Spirito”, Gastroenterology, Pescara, Italy, 10University of “Tor Vergata”, Gastroenterology, Rome, Italy, 11Ospedale S.S. Trinità, Gastroenterology, Borgomanero, Italy, 12University of Padua, Gastroenterology, Padua, Italy, 13AbbVie Inc, Global Medical Affairs, North Chicago, IL, United States, 14Azienda Ospedaliera per l'emergenza “Cannizzaro”, IBD Unit, Catania, Italy

P412. Personality trait in patients with inflammatory bowel disease, a prospective case–control study