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P111
Differences in therapies and intestinal resection rates between adult and elderly onset Crohn’s disease
C. Alexakis*1, S. Saxena2, V. Chhaya1, E. Cecil2, R. Pollok1
1St George’s Hospital, Gastroenterology, London, United Kingdom, 2Department of Primary Care and Public Health, Imperial College, London, United Kingdom
P112
Validation of the simplified Geboes score for ulcerative colitis
A. Jauregui-Amezaga*1, Y. Das2, T. Lobatón3, B. Lemmens2, T. Bessissow4, M. Ferrante1, G. Van Assche1, R. Bisschops1, K. Geboes2, G. De Hertogh2, S. Vermeire1
1University Hospitals Leuven, Gastroenterology, Leuven, Belgium, 2University Hospitals Leuven, Pathology, Leuven, Belgium, 3Hospital Universitari Germans Trias i Pujol, Gastroenterology, Badalona, Spain, 4Mc Gill University Health Centre, Gastroenterology, Montreal, Canada
P113
Quality of life in paediatric Crohn’s disease: data from the Imagekids study
V. M. Navas-López*1, 2, J. Martín-de-Carpi3, A. Grant4, T. D. Walters5, F. Ruemmele6, D. Mack7, M. Sladek8, R. Shamir9, R. Shaoul10, S. Saeed11, R. K. Russell12, R. Cytter-Kuint13, A. Griffiths14, D. Turner13, A. Otley4
1Paediatric Gastroenterology and Nutrition Unit, Hospital Materno Infantil, Málaga, Spain, 2IBIMA, Biomedical Institute of Málaga, Málaga, Spain, 3Unit for the Comprehensive Care of Paediatric Inflammatory Bowel Disease, Department of Paediatric Gastroenterology, Hepatology and Nutrition, Barcelona, Spain, 4IWK Health Centre, Halifax, Nova Scotia, Canada, 5Hospital for Sick Children, Toronto, Ontario, Canada, 6Hôpital Necker-Enfants Malades, Paris, France, 7Children’s Hospital of Eastern Ontario, Ottawa, Ontario, Canada, 8Jagiellonian University Medical College, Krakow, Poland, 9Schneider Children’s Medical Centre, Petach Tikvah, Israel, 10Rambam Health Care Campus, Haifa, Israel, 11Cincinnati Children’s Hospital Medical Centre, Cincinnati, Ohio,United States, 12Royal Hospital for Children, Glasgow, United Kingdom, 13Institute of Paediatric Gastroenterology, Shaare Zedek Medical Centre, The Hebrew University of Jerusalem, Jerusalem, Israel, 14Hospital for Sick Children, Toronto, Canada
P114
Predictors of clinical response during adalimumab therapy in Crohn’s disease patients: a German non-interventional study
I. Blumenstein*1, R. Atreya2, G. Greger3, B. Bokemeyer4, P. Nurwakagari3, M. F. Neurath2, B. Wittig3
1Goethe-University Frankfurt, Gastroenterology, Frankfurt am Main, Germany, 2University Erlangen, Erlangen, Germany, 3AbbVie Deutschland GmbH & Co.KG, Wiesbaden, Germany, 4Gastroenterology Practice, Minden, Germany
P115
Standardising assessment and documentation of pouchoscopy
V. A. van der Ploeg1, Y. Maeda*1, O. D. Faiz1, A. L. Hart2, S. K. Clark1
1St Mark’s Hospital, Department of Surgery, Harrow, United Kingdom, 2St Mark’s Hospital, Department of Gastroenterology, Harrow, United Kingdom
P116
Usefulness of consecutive faecal calprotectin measurements to predict relapse in inflammatory bowel disease patients under maintenance treatment with anti-TNF therapy: a prospective longitudinal cohort study
R. Ferreiro*, M. Barreiro-de Acosta, A. Lorenzo, J. E. Dominguez-Munoz
University Hospital Santiago de Compostela, Gastroenterology, Santiago, Spain
P117
Comparison between calprotectin and HMGB1 as faecal biomarkers of intestinal inflammation in paediatric and adult inflammatory bowel disease
F. Palone*1, R. Vitali1, L. Stronati2, R. D’Incà3, A. Armuzzi4, B. Barberio3, C. Felice4, D. Pugliese4, A. Dilillo5, M. Mennini5, S. Cucchiara5
1ENEA, Department of Radiobiology and Humal Health, Rome, Italy, 2Sapienza University of Rome, Department of Cellular Biotechnology and Haematology, Rome, Italy, 3University of Padova, Department of Surgical, Oncological and Gastroenterological Sciences, Padova, Italy, 4Internal Medicine and Gastroenterology - Complesso Integrato Columbus - Catholic University, Department of Internal Medicine, Rome, Italy, 5Sapienza, Rome, Paediatric Gastroenterology and Liver Unit, Rome, Italy
P118
Difference of health-related quality of life between East and South Asian incident inflammatory bowel disease patients and factors associated with improvement of HRQoL at follow-up: analysis of an Asia-Pacific population-based cohort
H. Chan*1, D. Ong2, Z. Zeng3, W. Tang1, J. Ching1, K. L. Goh4, I. Hilmi4, P. Pisespongsa5, S. Aniwan6, J. Limsrivilai7, J. De Silva8, M. Niriella8, Y. F. Wang9, O. Qin9, K. Wu10, M. Abdullah11, M. Simadibrata11, H. H. Yu12, K. K. Ng13, K. L. Ling14, M. H. Chen3, J. J. Sung1, S. Ng1
1Institute of Digestive Disease, the Chinese University of Hong Kong, Hong Kong, China, 2National University Hospital of Singapore, Singapore, 3The First Affiliated Hospital of San Yat Sen University, Guangzhou, China, 4University of Malaya Medical Centre, Kuala Lumpur, Malaysia, 5Maharaj Nakorn Chiangmai Hospital, Chiangmai, Thailand, 6King Chulalongkorn Memorial Hospital, Bangkok, Thailand, 7Siriraj Hosptial, Bangkok, Thailand, 8Colombo North Teaching Hospital, Ragama, Sri Lanka, 9West China Hospital, Sichuan University, Chengdu, China, 10Department of Gastroenterology, Xijing Hospital, Fourth Military Medical University, Shaanxi, China, 11Faculty of Medicine Universitas Indonesia/Dr Cipto Mangunkusumo Hospital, Depok Municipality, Indonesia, 12Kiangwu Hospital, Macau, Macao, 13Hospital Conde S Januario, Macau, Macao, 14Singapore General Hospital, Singapore, Singapore
P119
Diagnostic performance of different calprotectin assays
A. A. Wulandari1, J. Schulz1, F. Hartmann2,3, A. Dignass2, 3, J. Stein*1,3
1DGD Clinics Sachsenhausen, Frankfurt/Main, Germany, 2Agaplesion Markus Krankenhaus, Frankfurt/Main, Germany, 3Interdisciplinary Crohn Colitis Centre Rhein-Main, Frankfurt/Main, Germany
P120
Faecal calprotectin and S100A12 detect the early response to treatment by quantifying colonic inflammation in patients with ulcerative colitis
T. Kobayashi*, T. Toyonaga, S. Kuronuma, O. Takeuchi, M. Nakano, E. Saito, S. Umeda, N. Watanabe, T. Hibi
Kitasato University Kitasato Institute Hospital, Centre for Advanced IBD Research and Treatment, Tokyo, Japan
P121
Patients’ point of view regarding acceptability and usefulness of inflammatory bowel diseases monitoring tools: results from a nationwide multicentre study (the ACCEPT study)
A. Buisson*1, 2, F. Gonzalez3, F. Poullenot4, S. Nancey5, E. Sollellis1, M. Fumery6, B. Pariente7, M. Flamant8, A. Bourreille9, G. Bonnaud10, S. Mathieu11, A. Thevenin12, M. Duruy13, J. FILIPPI14, F. L’hopital15, F. Luneau16, V. Michalet15, J. Genès15, A. Achim17, E. Cruzille15, G. Bommelaer1, 2, D. Laharie18, L. Peyrin-Biroulet19, B. Pereira20, M. Nachury21, G. Bouguen22
1University Hospital Estaing, Gastroenterology Department, Clermont-Ferrand, France, 2UMR 1071 Inserm/Université d’Auvergne; USC-INRA 2018, Microbes, Intestine, Inflammation and Susceptibility of the Host, Clermont-Ferrand, France, 3Private practice, Nimes, France, 4University Hospital, Gastroenterology Department, Bordeaux, France, 5Hospices Civils de Lyon, Lyon-Sud Hospital, Gastroenterology, Pierre Benite, France, 6University Hospital, Gastroenterology Department, Amiens, France, 7University Hospital, Gastroenterology Department, Lille, France, 8Private practice, Nantes, France, 9University Hospital, Gastroenterology Department, Nantes, France, 10Private practice, Cornebarrieu, France, 11Private practice, Clermont-Ferrand, France, 12Private practice, St Quentin, France, 13Private practice, Arles, France, 14Archet 2 University Hospital, Department of Gastroenterology, Nice, France, 15Private practice, Riom, France, 16Private practice, Chateauroux, France, 17Private practice, Beaumont, France, 18University Hospital, Bordeaux, France, 19CHU Nancy Brabois, Department of Gastroenterology, Vandoeuvre les Nancy, France, 20GM – Clermont-Ferrand University and Medical Centre, Biostatistics Unit , Clermont-Ferrand, France, 21University Hospital of Lille, Gastroenterology, Lille, France, 22University Hospital, Rennes, France
P122
Role of diffusion-weighted imaging in MRI-enterography for the evaluation of surgical risk in patients with Crohn’s disease
A. Testa*1, A. Rispo1, P. Mainenti2, D. Musto1, N. Imperatore1, M. Rea1, O.M. Nardone1, M. L. Taranto1, F. Castiglione1
1University ‘Federico II’ of Naples, Department of Clinical Medicine and Surgery, Naples, Italy, 2University ‘Federico II’ of Naples, Naples, Italy
P123
Significance of serological markers in the disease course of ulcerative colitis
G. Kovacs*1, N. Sipeki1, K. Palatka1, I. Altorjay1, K. Fechner2, G. L. Norman3, Z. Shums3, G. Veres4, P. L. Lakatos5, M. Papp1
1University of Debrecen, Clinical Centre, Department of Internal Medicine, Division of Gastroenterology, Debrecen, Hungary, 2Institute of Experimental Immunology, Euroimmun AG, Lubeck, Germany, 3Inova Diagnostics, Inc., San Diego, California, United States, 4Semmelweis University, First Department of Paediatrics, Budapest, Hungary, 5Semmelweis University, First Department of Medicine, Budapest, Hungary
P124
Systematic review of the impact of psychological morbidity and associated risk factors in young people with inflammatory bowel disease
A. J. Brooks*1, G. Rowse2, A. Ryder2, E. J. Peach2, B. M. Corfe3, A. J. Lobo1
1Sheffield Teaching Hospitals NHS Foundation Trust, Academic Department of Gastroenterology, Sheffield, United Kingdom, 2University of Sheffield, Department of Psychology, Sheffield, United Kingdom, 3University of Sheffield, Department of Oncology, Sheffield, United Kingdom
P125
Investigating the small bowel in paediatric Crohn’s disease: prospective comparative study between small intestine contrast ultrasonography and magnetic resonance imaging
F. Civitelli*1, F. Maccioni2, S. Oliva1, M. Aloi1, A. Dilillo1, E. Casciani3, F. Viola1, S. Cucchiara1
1Sapienza University, Paediatric Gastroenterology and Liver Unit, Rome, Italy, 2Sapienza University, Department of Radiological Sciences, Oncology, and Pathology, Rome, Italy, 3University of Rome Sapienza, Department of Emergency Radiology, Rome, Italy
P126
IBD-related malignancies and mortalities observed in 2015: first results from the prospective nationwide Hungarian registry
T. Molnar*1, F. Nagy1, P. Fitz2, L. Lakatos3, P. Miheller4, T. Szamosi5, A. Vincze6, J. Banai5, A. Kovács7, J. Novák8, A. Salamon9, A. Szepes10, N. Szigeti11, M. Juhász4, K. Müllner4, O. Kadenczki12, M. Rutka1, A. Bálint1, R. Bor1, A. Milassin1, Z. Szepes1, K. Farkas1
1University of Szeged, First Department of Medicine, Szeged, Hungary, 2St. Francis Hospital, Kalocsa, Hungary, 3Csolnoky Ferenc Veszprém County Hospital, Veszprém, Hungary, 4Semmelweis University, 2nd Department of Medicine, Budapest, Hungary, 5State Health Centre, Department of Gastroenterology, Budapest, Hungary, 6University of Pécs, First Department of Internal Medicine, Pécs, Hungary, 7Péterfy Sándor Hospital and Trauma Centre, Budapest, Hungary, 8Bekes County Pandy Kalman Hospital, Gyula, Hungary, 9Tolna County Balassa Janos Hospital, Gastroenterology Department, Szekszárd, Hungary, 10Bács-Kiskun County University Teaching Hospital, Kecskemét, Hungary, 11University of Pécs, Second Department of Internal Medicine and Nephrology Centre, Pécs, Hungary, 12University of Debrecen, Debrecen, Hungary
P127
Predictive role of penetrating disease behaviour, ileal localisation, female gender, and plexitis in the postoperative recurrence of Crohn’s disease
A. Milassin*1, A. Sejben2, Z. Reisz2, L. Tiszlavicz2, G. Lázár3, R. Bor1, A. Bálint1, M. Rutka1, Z. Szepes1, K. Farkas1, T. Molnár1
1University of Szeged, First Department of Internal Medicine, Szeged, Hungary, 2University of Szeged, Department of Pathology, Szeged, Hungary, 3University of Szeged, Department of Surgery, Szeged, Hungary
P128
Faecal calprotectin has an acceptable sensitivity for detecting small bowel Crohn’s disease: results from real-world clinical practice
J. Wu*, E. Harrison, C. S. Chey, H. Johnson, S. Weaver, S. Mclaughlin
The Royal Bournemouth and Christchurch Hospitals NHS Foundation Trust, Gastroenterology, Bournemouth, United Kingdom
P129
Factors associated with anxiety and depression in Korean inflammatory bowel disease patients
S.-K. Park*, Y. S. Jung, D. I. Park
Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea
P130
Anxiety and depression may lead to poor health-related quality of life in patients with inflammatory bowel disease
U. Chauhan*1, Y. Farbod2, D. Armstrong2, S. L. Halder2, S. Kaasalainen3, J. K. Marshall2, J. Popov2, F. Tse2, P. Moayyedi2
1McMaster University Medical Centre, Digestive Disease, Hamilton, Canada, 2McMaster University, Department of Gastroenterology, Hamilton, Canada, 3McMaster University, School Of Nursing, Hamilton, Canada