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P334. The safety of immunomodulators and anti-TNF drugs for the treatment of inflammatory bowel disease (IBD) during pregnancy
P334. Three-year clinical follow-up in a Swedish cohort of patients with newly diagnosed ulcerative colitis
Authors:

H. Strid1, L. Öhman1, A. Bajor1, A. Lasson2, J. Svedlund3, M. Simrén1, 1Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Department of Internal Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden, 2Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Department of Internal Medicine, Södra Älvsborgs hospital, Borås, Borås, Sweden, 3Institute of Neuroscience and Physiology, Gothenburg, Sweden, Department of Psychiatry, Sahlgrenska University Hospital, Gothenburg, Sweden

P334

Level of education and knowledge about female health issues in patients with inflammatory bowel disease.

Authors:

S. Chetcuti Zammit1, M. Caruana1, K.H. Katsanos2, G.J. Mantzaris3, M. Cesarini4, U. Kopylov5, L. Zammit1, P. Ellul*1

1Mater Dei Hospital, Department of Gastroenterology, Msida, Malta, 2University of Ioannina School of Medical Sciences, Department of Internal Medicine, Medical School, Ioannina, Greece, 3Evangelismos, Ophthalmiatreion Athinon and Polyclinic Hospitals, Department of Gastroenterology, Athens, Greece, 4Sapienza University of Rome, Dipartimento di Medicina Interna e Specialità' Mediche, Rome, Italy, 5Sheba Medical Center, Department of Gastroenterology, Tel Hashomer, Israel

P335.

Two-year efficacy and safety of azathioprine treatment in the maintenance of steroid-free remission in inflammatory bowel disease patients

Authors:

C. Cassieri, R. Pica, E.V. Avallone, M. Zippi, C. Corrado, P. Vernia, P. Paoluzi, E.S. Corazziari, “Sapienza”, Department of Internal Medicine and Medical Specialties, Rome, Italy

P335. How is the coping in patients with inflammatory bowel disease?
P335. Patients' perspectives of faecal transplantation for pouchitis
P335. Thiopurine nonadherence is more common in adolescents than adults with IBD, is associated with psychological distress and impacts on the management and prognosis
Authors:

J. Goodhand1, N. Kamperidis1, B. Sirwan1, L. Macken1, N. Tshuma1, Y. Koodun1, F. Chowdhury1, N. Croft1, N. Direkze1, L. Langmead1, P. Irving2, D. Rampton1, J. Lindsay1, 1Barts and The London SMD, Gastroenterology, London, United Kingdom, 2Guy's and St Thoma's School of medicine, Gastroenterology, London, United Kingdom

P335

Screening for enteric infection in inflammatory bowel disease patients contacting the IBD helpline and presenting with disease flares

Authors:

H. Johnson, K. Wade*, S. Weaver, S. McLaughlin

Royal Bournemouth Hospital, Department of Gastroenterology, Bournemouth, United Kingdom

P336.

TNF alpha inhibitor use in pregnancy: experience in a European cohort

Authors:

O. Kelly1,2, K. Hartery3, K. Boland1, G. Cullen1, D. Keegan1, S. Patchett3, M. Forry3, H. Mulcahy1, G. Doherty1, 1St Vincent's University Hospital, Department of Gastroenterology, Dublin, Ireland, 2St Vincents University Hospital, Gastroenterology, Dublin, Ireland, 3Beaumont Hospital, Gastroenterology, Dublin, Ireland

P336. Experimental inflammatory bowel disease registry: Incidence and prevalence in Forli' district in Italy (1993–2009)
P336. The effect of granulocyte and monocyte adsorption for Crohn's disease patients with loss of response or adverse events for anti‑TNF‑α therapy
P336. The use of TPMT enzyme testing in managing thiopurine therapy
Authors:

M. Widlak1, M. Smith1, J. Slater1, L. Wood1, S. De Silva1, 1Russells Hall Hospital, Gastroenterology, Dudley, United Kingdom

P336

Intestinal transplantation for Crohn's Disease: The Cambridge experience since 2008

Authors:

T. Ambrose*, L. Sharkey, J. Louis-Auguste, C. Rutter, R. Prasad, D. Massey, N. Russell, A. Butler, J. Woodward, S. Middleton

Summary of cases

Case1234567
GenderMaleFemaleFemaleFemaleFemaleMaleMale
Age at transplant35643752616050
Montreal classificationA1L3B3pA2L3B3pA1L3B2A2L3B3pA2L3B3A1L3B2A2L3B2
Anatomy from DJF50cm to end jejunostomy, and left colon (not in continuity)60cm to colon with end colostomy120cm to full colon20cm to jejunostomy100cm to ileostomy120cm to ileostomy70cm to colon with end colostomy
Years from diagnosis to commencing PS18261110344213
Years on PS pre-transplant313102210311
IndicationShort gut with IFALDLoss of vascular accessLoss of vascular accessShort gut with IFALDEnd stage renal failure; SB/colon needed for enteral fluid managementNAFLD cirrhosis with short gutRecurrent line infections
Organs transplantedSt, SB, liver, pancreasSB1) SB; 2) SB, kidneySt, SB, liver, pancreas, kidneySB, colon, kidneySB, liver, pancreasSB, colon, pancreas
Year of transplant20082010Both 20102011201320132014

Key to table: DJF = duodenojejunal flexure, NAFLD = non-alcoholic fatty liver disease, SB = small bowel, St = stomach Case 3: 2nd transplant performed for rejection (non-compliance with immunosuppression)

Cambridge University Hospitals NHS Foundation Trust, Department of Intestinal Transplantation, Cambridge, United Kingdom

P337.

TNF-alpha as induction therapy for Crohn's disease: a comparison of adalimumab and infliximab – a prospective observational study in Germany

Authors:

B. Bokemeyer1, U. Helwig2, N. Teich3, C. Schmidt4, T. Krummenerl5, A.-K. Rupf6, H. Hartmann7, M. Bläker8, A. Krummenerl9, M. Düffelmeyer10, R. Hinrichs11, P. Hartmann12, S. Nikolaus13, D. Hüppe7, S. Schreiber13, 1Gastroenterology Practice Minden, University Hospital Schleswig-Holstein, Department of General Internal Medicine I, Kiel, Germany, Minden, Germany, 2Gastroenterology Practice, Gastroenterology, Oldenburg, Germany, 3Gastroenterology Practice Leipzig, Gastroenterology, Leipzig, Germany, 4University of Jena, Gastroenterology Department, Jena, Germany, 5Gastroenterology Practice, Gastroenterology, Münster, Germany, 6Frierichshafen Hospital, Department of General Internal Medicine I, Friedrichhafen, Germany, 7Gastroenterology Practice Herne, Gastroenterology, Herne, Germany, 8Gastroenterology Practice Hamburg, Gastroenterology, Hamburg, Germany, 9Hospital Matha-Maria Halle-Dölau, Department of General Internal Medicine I, Hall (Saale), Germany, 10IOMTech GmbH, Software FORGA UG, Berlin, Germany, 11Competence Network on IBD, Germany, Kiel, Germany, 12Gastroenterology Practice Minden, Gastroenterology, Minden, Germany, 13Christian-Albrechts-Universität, University Hospital Schleswig-Holstein, Department of General Internal Medicine I, Kiel, Germany

P337. Incidental diagnosis of inflammatory bowel disease during bowel cancer screening programme in Northeast Italy
P337. Maintenance treatment of chronic refractory IBD-patients with granulocyte/monocyte adsorption
P337. The switching therapy between infliximab and tacrolimus in steroid-refractory ulcerative colitis
Authors:

K. Kimura1, K. Matsuoka1, J. Miyoshi1, S. Mizuno1, N. Inoue2, M. Naganuma3, T. Hisamatsu1, T. Yajima1, T. Kanai1, H. Ogata3, Y. Iwao2, T. Hibi1, 1Keio University School of Medicine, Department of Gastroenterology and Hepatology, Division of Internal Medicine, Tokyo, Japan, 2Keio University Hospital, Center for Preventive Medicine, Tokyo, Japan, 3Keio University School of Medicine, Center for Diagnostic and Therapeutic Endoscopy, Tokyo, Japan

P337

Profile and outcomes of mercaptopurine therapy in inflammatory bowel disease

Authors:

F. Berrmejo*1, A. Algaba1, S. López-Durán2, I. Guerra1, M. Aicart2, M. de Lucas1, E. Garrido2, M. Hernández1, A. López-Sanromán2

1Hospital Universitario de Fuenlabrada, Gastroenterology, Madrid, Spain, 2Hospital Universitario Ramón y Cajal, Gastroenterology, Madrid, Spain

P338.

Systematic versus endoscopy-driven treatment with azathioprine to prevent postoperative ileal Crohn's disease recurrence

Authors:

M. Ferrante1, K. Papamichael2, D. Duricova3, G. D'Haens4,5, S. Vermeire1, E. Archavlis2, P. Rutgeerts1, M. Bortlik3, G. Mantzaris2, G. Van Assche1, 1University Hospitals Leuven, Department of Gastroenterology, Leuven, Belgium, 2Evangelismos Hospital, A' Department of Gastroenterology, Athens, Greece, 3Univerzity Karlovy, Department of Gastroenterology, Prague, Czech Republic, 4Imelda Hospital, Imelda GI Clinical Research Center, Bonheiden, Belgium, 5Academic Medical Center, Department of Gastroenterology, Amsterdam, Netherlands

P338. Impact of inflammatory bowel disease on sexual function