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P262. Patient weight predicts time to loss of response with adalimumab in Crohn's disease
P262. Patients with refractory pouchitis receiving adalimumab may avoid permanent ileostomy
P262

Protein biomarker measurement in non-invasively collected colonic mucus samples as a new approach to inflammatory bowel disease (IBD) detection.

Authors:

A. Loktionov*1, V. Chhaya2, T. Bandaletova1, A. Poullis2

1DiagNodus Ltd, N/A, Cambridge, United Kingdom, 2St George's NHS Trust, Gastroenterology, London, United Kingdom

P263.

Clinical impact of magnifying chromoendoscopy on assessment of mucosal healing and prediction of disease relapse in quiescent ulcerative colitis

Authors:

M. Matsuura1, H. Nakase2, T. Yoshino1, T. Chiba1, 1Kyoto University Hospital, Department of Gastroenterology and Hepatology, Kyoto, Japan, 2Kyoto University Hospital, Division of Endoscopic Medicine, Kyoto, Japan

P263. Definition of phenotypic characteristics of late onset IBD
Authors:

A. McNichol1, S. Din1, M. Porteous1, C. Lees1, J. Satsangi2, I. Arnott1, 1NHS Lothian, GI Unit, Edinburgh, United Kingdom, 2University of Edinburgh, GI Unit, Edinburgh, United Kingdom

P263. Elaboration and validation of a questionnaire to evaluate patients satisfaction with healhtcare services: CACHE questionnaire
P263. Long-term clinical experience with vedolizumab for the treatment of inflammatory bowel disease: A phase 2 open-label safety extension study
P263

Agreement between on-line patient reported and onsite physician assessed activity on the Simple Clinical Colitis Activity Index (SCCAI) domains. CRONICA-UC study

Authors:

J. Panés*1, E. Domènech2, P. Nos3, I. Marín-Jiménez4, S. Riestra5, J.P. Gisbert6, D. Carpio7, X. Cortés8, E. Iglesias9, B. Juliá10, C. Romero10, A. Subtil10, O. Rincón10, L. Cea-Calvo10

1Hospital Clinic Universitario de Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain, 2Hospital Universitari Germans Trias i Pujol and CIBERehd, Gastroenterology Unit, Badalona, Spain, 3Hospital Universitari I Politècnic La Fe, Gastroenterology Unit, Valencia, Spain, 4Hospital General Universitario Gregorio Marañón, Gastroenterology Unit, Madrid, Spain, 5Hospital Central de Asturias, Gastroenterology unit, Oviedo, Spain, 6Hospital La Princesa , IP and CIBERehd, Gastroenterology Unit, Madrid, Spain, 7Complejo Hospitalario de Pontevedra, Gastroenterology Unit, Pontevedra, Spain, 8Hospital de Sagunto, Gastroenterology Unit, Sagunto, Spain, 9Hospital Universitario Reina Sofia, Unidad Clinica de Aparato Digestivo, Cordoba, Spain, 10MSD Spain, Medical Department, Madrid, Spain

P264. 30-day response to steroids predicts long term natural history of ulcerative colitis
P264.

Clinical features and prognosis of fistulizing perianal Crohn's disease in Korea

Authors:

J. Chun1, S.W. Hwang1, J.H. Kim1, J.P. Im1, B.D. Ye2, J.W. Kim3, Y.S. Kim4, J.S. Kim5, 1Seoul National University College of Medicine, Internal Medicine and Liver Research Institute, Seoul, Korea, Republic of, 2University of Ulsan College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 3Seoul National University Boramae Hospital, Seoul National University College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 4Inje University College of Medicine, Internal Medicine, Seoul, Korea, Republic of, 5Seoul National Uinversity College of Medicine, Internal Medicine and Liver Research Institute, Seoul, Korea, Republic of

P264. Crohn's disease endoscopic post-operative recurrence is associated with a cytotoxic CD8+ T cells enrichment in blood and gut lamina propria
Authors:

G. Boschetti1, S. Nancey1, D. Moussata1, E. Cotte2, A.-L. Charlois3, I. Graber1, D. Kaiserlian4, B. Flourié1, 1Lyon-Sud Hospital, Gastroenterology, Pierre-Bénite, France, 2Lyon-Sud Hospital, Digestive Surgery, Pierre-Bénite, France, 3Lyon-Sud Hospital, Statistics, Pierre-Bénite, France, 4Inserm, U 851, Lyon, France

P264. Cytokine ratios in Crohn's disease clinical remission before and after the intake of a probiotic
P264

Revised Predictive Values for IBD Colitis-associated Neoplasia in the Modern Era

Authors:

N. Krugliak Cleveland*1, R. Colman2, D. Rodriquez2, A. Hirsch2, J. Hart2, D. Rubin2

1University of Illinois at Chicago, College of Medicine, Chicago Il, United States, 2University of Chicago, Inflammatory Bowel Disease Center, Chicago, United States

Comparison of Colonoscopy Findings and Colectomy Findings in 35 IBD Patients

Index Grade of NeoplasiaPrimary Lesion at ColonoscopyIndex Lesion Found at ColectomyUpstage or Downstage Index Lesion?Synchronous Lesion at ColectomyGrade of Synchronous Lesions at Colectomy
LGD24/3511/240/117/244 LGD, 3 HGD, 0 CA
HGD4/353/41/3 upstage (CA)1/40 LGD, 0 HGD, 1 CA
Cancer (CA)7/355/71/5 downstage (HGD)2/71 HGD, 1 CA
P265.

Clinical characteristics and oncologic outcomes in patients with colorectal cancer complicating ulcerative colitis: a single-institution experience

Authors:

N. Dimitriou, D. Liakopoulos, A. Miller, M. Norwood, University Hospital Leicester, Leicester Royal Infirmary-Colorectal unit, Leicester, United Kingdom

P265. Cost-effectiveness of surgery and infliximab for refractory ulcerative colitis: a single centre study using patient-level data
Authors:

N. Arebi1, D. Karapiperis1, S. Tripoli1, N. Poonja1, 1St Mark's Hospital, London, United Kingdom

P265. Preoperative infliximab therapy and postoperative complications after proctocolectomy with ileum pouch anal anastomosis (IPAA)
P265. Work productivity and activity impairment in Spanish Crohn's disease patients
P265

Decreased plasma ADAMTS13 antigen and ADAMTS13 activity as a risk factor for hypercoagulability in patients with ulcerative colitis.

Authors:

D. Owczarek1, D. Cibor*2, K. Salapa1, T. Rodacki1, R. Domagala-Rodacka3, T. Mach2, A. Undas1

1Jagiellonian University Medical College, Cracow, Poland, Insitute of Cardiology, Cracow, Poland, 2Jagiellonian University Medical College, Cracow, Poland, Gastroenterology, Hepatology and Infectious Diseases, Cracow, Poland, 3Master , of Pharmacy, Cracow, Poland

P266.

Chronic inflammatory bowel disorders diagnosed by screening colonoscopy for health check-up

Authors:

N. Inoue, Y. Iwao, J. Matsuzaki, N. Takada, E. Shiomi, R. Shimizu, T. Yoshida, M. Takayama, Y. Sugino, Keio University School of Medicine, Center for Preventive Medicine, Tokyo, Japan

P266. Correlation of clinical symptoms to current biomarkers of intestinal inflammation in patients with Crohn's disease
Authors:

J. Chang1, N. Kennedy1, F. Fascí Spurio1, M. Muscat1, M. Guy1, J. Satsangi1, I. Arnott1, K. Kingstone1, C.W. Lees1, 1Western General Hospital, Gastroenterology, Edinburgh, United Kingdom